Systems and methods are provided for treating or preventing carbon monoxide poisoning. In particular, systems and methods are provided for a phototherapy treatment or prevention system that delivers light radiation to a patient's body to photodissociate carbon monoxide from hemoglobin.

A method for controlling gas composition in a surgical cavity during an endoscopic surgical procedure includes monitoring for a plurality of gas species in a gas flow from a surgical cavity of a patient. The method includes measuring the plurality of gas species in the gas flow from the surgical cavity and determining if the gas species measured in the gas flow from the surgical cavity are each present and/or within a respective desired range. The method includes adding gas into the surgical cavity if one or more gas species in the plurality of gas species is outside of the respective desired range so as to bring a composition of gas species in the surgical cavity within the respective desired range.

A therapeutic vaporizer inhalation bag attachment system with an integrated valve is disclosed. The attachment system includes a body having a lumen extending between the two openings of the body, a bag coupling, and a valve positioned within the lumen. A method of using the inhalation bag attachment system is also disclosed.

An air treatment unit may include an air inlet to receive a flow of input air for treatment and a reaction reservoir configured to hold an aqueous air treatment solution. The air treatment unit may also include an air dispersing element flow connected with the air inlet, wherein the air dispersing element is configured to convert at least a portion of the flow of input air into a plurality of microbubbles for introduction into the aqueous air treatment solution, such that an amount of one or more target gas species contained within the plurality of microbubbles is reduced through reaction with the aqueous air treatment solution. The unit may include an air outlet configured to output treated air from the reaction reservoir.

An exposure cell and method for treatment of carbon monoxide poisoning in the blood of a living body by removal of a portion of blood from the body, placing the portion in the exposure cell, exposing the portion in the cell to light of wave length and intensity that causes dissociation of carbon monoxide from hemoglobin, and returning the portion to the body. The exposure cell has an exposure zone outside of the body, that holds the portion, and a window that allows light from outside the zone to enter the zone to disassociate carbon monoxide from the portion. Oxygen is injected into the zone and carbon monoxide is removed from the zone.

Treatment of carbon monoxide poisoning of a body by removal of a portion of the blood from the body, placing the portion in an exposure cell, exposing the portion in the cell to light of wave length and intensity that causes dissociation of carbon monoxide from hemoglobin, and returning the portion to the body. The intensity and wave length of the light is sufficient to dissociate a therapeutically-effective amount of carbon monoxide from the hemoglobin in the blood. The blood is circulated from and to the body through a concentric double lumen cannula. The wave lengths of the light are 540 and/or 570 nanometers. The cell exposes the blood to at least 9.5 Joules of dissociative light per milliliter of blood, and least 9.5 Watts of dissociative light per milliliter of blood per second. Oxygen is provided to, and the dissociated carbon monoxide is removed from the system.

Systems and methods for removing carbon monoxide from whole blood are provided. In one configuration, an extracorporeal phototherapy system includes an oxygenator and a light source configured to output light and arranged to emit the light output by the light source onto at least one surface of the oxygenator. The oxygenator includes a plurality of membrane layers each having a plurality of microporous hollow fiber membranes. The plurality of microporous hollow fiber membranes each include an external surface and an internal channel. Each of the plurality of membrane layers may be rotationally offset with respect to an adjacent layer. The oxygenator further includes a gas inlet port in fluid communication with a first end of the internal channels, a gas outlet port in fluid communication a second end of the internal channels, a blood inlet port, and a blood outlet port.

Methods and systems for delivering a pharmaceutical gas to a patient. The methods and systems provide a known desired quantity of the pharmaceutical gas to the patient independent of the respiratory pattern of the patient over a plurality of breaths every n.sup.th breath, where n is greater than or equal to 1. The pharmaceutical gases include CO and NO, both of which are provided as a concentration in a carrier gas. The gas control system determines the delivery of the pharmaceutical gas to the patient to result in the known desired quantity (e.g. in molecules, milligrams or other quantified units) of the pharmaceutical gas being delivered. Upon completion of that known desired quantity of pharmaceutical gas over a plurality of breaths, the system can either terminate, continue, activate and alarm, etc.

A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect a treatment of a person, such as by initiating, pausing, halting or adjusting a dosage of drugs administered to the person.

A therapeutic vaporizer inhalation bag attachment system with an integrated valve includes a body having a lumen extending between the two openings of the body, a bag coupling, and a valve positioned within the lumen. A first end of the body may include a mouthpiece and the second end of the body may include bag coupling to attach an inhalation bag. The body may include a plurality of cooling ribs extending in parallel with the lumen along an outer surface of a sidewall of the body. The valve may be a duck-bill valve configured to move between a first position which allows flow of vapor through the lumen in a first direction extending from the first opening to the second opening, and a second position which prevents substantial flow of vapor through the lumen in a second direction from the second opening to the first opening, the valve having two flaps extending within the lumen inwardly from an inner sidewall of the body