The present invention relates to a method for separating lymphocytes and/or stem cells from whole blood in an automated blood separation system, wherein the quality of the collected lymphocytes and/or stem cells fractions is increased and the cell collection procedure is further automated by use of an optical sensor comprised in a detector device to measure turbidity and colour in the claimed method and in a cell separator, which can be used to perform the claimed method. The method of the invention is particularly useful to collect lymphocytes and/or stem cells fractions from whole blood, wherein the contamination of the collected cell fractions by platelets, red blood cells and granulocytes is reduced.

Provided is a blood filter that resists deterioration in properties as a result of electron beam sterilization treatment performed before or during use as a blood filter, has durability, dimensional stability, and chemical resistance at excellent levels, also has biocompatibility, and resists deterioration in properties even upon the electron beam sterilization treatment. The blood filter according to the present invention includes a nonwoven fabric made of PEEK fibers. Preferably, the blood filter according to the present invention has an average pore size of 3 to 280 μm and has a porosity of 15% to 70%; and the PEEK fibers have an average fiber diameter of 10 μm or less.

A carrier for blood component adsorption includes a water-insoluble carrier composed of a fiber or particle, the water-insoluble carrier having a surface to which a functional group(s) is/are introduced, the functional group(s) containing an acidic functional group selected from the group consisting of the sulfate group, sulfite group and sulfonate group; and containing an amino group; the fiber having a fiber diameter of, or the particle having a particle diameter of, 0.5 to 20 μm.

A peritoneal dialysis (PD) fluid line set includes a fluid line configured to carry spent dialysate to a drain receptacle and a chemical testing device disposed along the fluid line. The chemical testing device is configured to detect a presence of a substance in the spent dialysate as the spent dialysate flows past the chemical testing device, and the chemical testing device is configured to provide a visual indicator of the presence of the substance in the spent dialysate.

Filter assemblies are processing biological fluid, such as blood or a blood component containing leukocytes. The filter assemblies include a flexible housing with first and second walls. A filtration medium and a support member are at least partially positioned between the walls of the housing, with a seal joining the walls of the housing, the filtration medium, and the support member. The filter assemblies may further include a pre-filter and/or a post-filter positioned between the walls of the housing. If provided, the pre- and post-filter may be positioned on opposite walls of the filtration medium, with the post-filter being a mesh positioned between the filtration medium and one of the walls of the housing or within an opening defined by the support member. A seal of the filter assembly may pass through the filtration medium, with the filtration medium being substantially omitted in a section of the seal.

The present invention relates to a buffy coat extraction kit including: a kit body having a cylindrical plasma part that has an internal volume for forming a plasma layer, a cylindrical buffy coat part which extends in the longitudinal direction while communicating with the lower part of the plasma part and has a diameter smaller than the diameter of the plasma part and an internal volume for forming a buffy coat layer, and a cylindrical erythrocyte part which extends in the longitudinal direction while communicating with the lower part of the buffy coat part and has a diameter larger than the diameter of the buffy coat part and an internal volume for forming an erythrocyte layer, wherein the free end part of the plasma part and the free end part of the erythrocyte part are respectively opened; a lower packing movably accommodated in the erythrocyte part while maintaining an air-tight state; and a pusher moving the lower packing.

A fluid processing system for controlling fluid flow comprises a cassette having a defined passageway on a first side. The first side includes flexible sheeting disposed over the passageway. The system comprises a durable processing device configured to engage the first side of the cassette, the durable processing device comprising a valve actuator configured to engage the flexible sheeting at a valve location along the passageway. The system comprises a first pump configured to draw fluid away from the valve location along the passageway. The first pump is disposed downstream of the valve location. The system comprises a second pump configured to pump fluid towards the valve location along the defined passageway. The second pump is disposed upstream of the valve location. The first and second pumps are configured to operate in concert and configured to provide pressure to prevent collapsing of the flexible sheeting against the passageway during operation.

A method and system for collecting leukoreduced red blood cells employing a spinning membrane separator including a housing having an upper end region and a lower end region in an operating position with a red blood cell outlet in the upper end region of the housing and a whole blood inlet in the lower end region of the housing. The method and system provide for flowing additive solution into the whole blood inlet of the housing to prime the separator; flowing whole blood into the whole blood inlet of the housing; separating red blood cells from the whole blood; flowing separated red blood cells out of the red blood cell outlet of the housing; combining the separated red blood cells with additive solution: passing the separated red blood cells and additive solution combination through a leukoreduction filter; and collecting the filtered red blood cells and additive solution.

Provided is a blood processing filter comprising a container having two spouts serving as an inlet for a liquid to be processed and an outlet for the processed liquid, and a filtration medium contained in the container, the filtration medium comprising a filter material having different CWST values for one surface A and the other surface B.

A blood component separator (1) includes a blood storage vessel (20) that includes a first storage part (21) and a second storage part (22), a slider (30) movable from the first storage part to the second storage part, and a flow path (40f) for communicating an inside and an outside of the storage vessel. When the slider is in the first storage part, the first storage part and the second storage part are in communication with each other. When the slider is inserted into the second storage part, a liquid-tight seal is formed between the slider and the inner peripheral surface of the second storage part and the communication between the first storage part and the second storage part is blocked by the slider. The slider is movable in the second storage part while maintaining the liquid-tight seal between the slider and the inner peripheral surface of the second storage part. As the slider enters the second storage part, the blood component in the second storage part is pushed out of the storage vessel through the flow path.