According to some embodiments, a system may treat blood outside the body of a patient. The system may include at least one toxin removal system configured to process blood from at least two places on the patient's body at a rate, for example, of at least 0.5 liters per minute. The system may be configured to raise the pH level of the patient's blood by introducing a fluid at rate of at least 9 liters per hour.

Syringe (1) having a syringe body (5) and a proximal syringe outlet (11) in the syringe body (5) as well as having a syringe plunger (7) being axially (13) movable in the syringe body, having a proximal end and a distal end, wherein an elongate lumen (14) is formed inside the syringe plunger (7) coming from the proximal end (7a) of the syringe plunger (7) until the distal end (7b) of the syringe plunger, in which a movable inner plunger (8) having a proximal end (8a) and a distal end (8b) is arranged.

A needle is provided that has terminals located at or near its tip. The terminals are connectable to an impedance calculating circuit configured to enable the impedance calculating circuit to apply an alternating current input electrical signal to the terminals. The terminals are further configured to enable the impedance calculating circuit to measure a resultant electrical signal and calculate an impedance of biological tissue surrounding the tip. The needle may further include light transmitting media, that extends along the needle, and that is connectable to a light circuit. The light circuit may include an emitter/detector pair for transmitting light from the emitter, along the media, and emitting the light from the tip. A reflection of the emitted light may be transmitted from the tip to the detector and the light circuit may calculate the light absorption of the tissue.

A system and method for delivering a medicament including a catheter configured for implantation in different target tissue sites, extending from a proximal end to a distal end, and having a sidewall which defines an internal lumen. The distal end has one or more apertures in the sidewall for the release of the medicament into the target tissue site; the system also comprises a medicament reservoir fluidly communicable with the internal lumen of each catheter, an adhesive member configured to adhere to the skin of the patient around the exit wound and having an opening therein to allow the catheters to pass through the adhesive member and a retaining member configured to be overlaid on the adhesive member and comprising a guide surface configured to receive a length of the two or more catheters and a plurality of retaining portions to retain the catheters against the guide surface.

A catheter housing device for securing a catheter and needle assembly to a patient. The device can include a cover, an IV/catheter lock, a hub, and one or more fastening straps. The device can replace conventional devices and techniques for securing a catheter and needle to a patient that utilize adhesive materials and/or methods, which are ill-equipped to solve complications including infection/contamination of the insertion site, irritation/damage to the vein or insertion site due to inappropriate angling of the catheter/needle, etc. The devices and methods disclosed herein can provide catheter/needle securement and optimal inclination, a hermetically sealed chamber to resist infection and/or contamination, inert gas or soothing anesthetic vapor drugs in and around the device, and various skin-contacting layers and structures that promote ventilation and patient comfort in and around the insertion site.

A drug delivery trocar is configured to deliver medication at an incision site during surgery so as to reduce post-surgical incisional pain. The trocar includes an elongate tube having a lumen, and a fluid reservoir attached or attachable to the lumen.

A syringe holder includes a syringe barrel holder having a depression which is configured to receive and engage finger tabs of a syringe and has a bottom depression surface engageable by the finger tabs. A barrel opening receives a barrel of the syringe, and includes a central longitudinal axis, a shaft channel and a set screw channel having a screw axis passing through the shaft channel. A dosing shaft extends from a first end to a second end and includes a plurality of notches between the ends. The dosing shaft is located and slideable within the shaft channel. A plunger cap includes a plunger receptacle and attaches to a first end of the dosing shaft. A socket set screw is located and engaged within the set screw channel and has a resilient end engageable with the notches of the dosing shaft.

Systems and instruments for medical procedures and methods relating thereto, such as, for example, those that can be used in minimally invasive medical procedures, among other procedures.

A painless infusion set has an affixed portion and may have a disposable or reusable insertion device portion. The infusion set or its inserter may have methods or mechanisms to utilize gas, liquid, gel, or solid within phase or through phase change with user-controlled variably slow insertion to reduce pain. In one example, a canister of a pain reducing material is in the insertion device. The pain reducing material can be dispensed onto the skin before, during, or after insertion of the needle or cannula to reduce pain.

An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.