The embodiments use an innovative approach with the goal of permanent eradication of the virus. Instead of using drugs that block different stages of the virus life cycle (which have failed to induce a permanent cure), or approaches attempting to track infected cells, the embodiments use small virucidal molecules that are known to destroy the virus in vitro and that can easily penetrate all human cells, including memory cells or other reservoir cells. The problem with the use of small molecules is their toxicity to humans or animals when administered in doses sufficient to achieve intracellular concentrations high enough to destroy the virus in all forms. The embodiments overcome these toxicities (especially the comatose state) by using a 24-hour treatment with general anesthesia, endotracheal intubation with hemodynamic support, and controlled monitored ventilation; also, a combination of these molecules are used which decreases toxicity but has additive virucidal effects.

The embodiments use an innovative approach with the goal of permanent eradication of the virus. Instead of using drugs that block different stages of the virus life cycle (which have failed to induce a permanent cure), or approaches attempting to track infected cells, the embodiments use small virucidal molecules that are known to destroy the virus in vitro and that can easily penetrate all human cells, including memory cells or other reservoir cells. The problem with the use of small molecules is their toxicity to humans or animals when administered in doses sufficient to achieve intracellular concentrations high enough to destroy the virus in all forms. The embodiments overcome these toxicities (especially the comatose state) by using a 24-hour treatment with general anesthesia, endotracheal intubation with hemodynamic support, and controlled monitored ventilation; also, a combination of these molecules are used which decreases toxicity but has additive virucidal effects.

A method of regulating pain in a patient includes operations of measuring a patient pain level, determining a dose of ethanol which does not trigger alcohol intolerance or intoxication, delivering the dose of ethanol to the patient by inhalation from an active mesh nebulizer at a repeated interval, measuring the pain level of the patient at a monitoring interval, and determining, based on the patient pain level, whether to adjust the ethanol dose. The dose of ethanol is delivered in the form of particles of nebulized liquid having a diameter ranging from about 0.5 μm to about 5.0 μm, which are rapidly absorbed into the bloodstream of a patient and delivered to the brain.

A method of regulating pain in a patient includes operations of measuring a patient pain level, determining a dose of ethanol which does not trigger alcohol intolerance or intoxication, delivering the dose of ethanol to the patient by inhalation from an active mesh nebulizer at a repeated interval, measuring the pain level of the patient at a monitoring interval, and determining, based on the patient pain level, whether to adjust the ethanol dose. The dose of ethanol is delivered in the form of particles of nebulized liquid having a diameter ranging from about 0.5 μm to about 5.0 μm, which are rapidly absorbed into the bloodstream of a patient and delivered to the brain.

A microstructure is provided. A microstructure according to an embodiment of the present invention comprises: a tip portion formed on a substrate and comprising a drug; and a separation portion which is formed between the substrate and the tip portion and, after the tip portion has been inserted into the skin, separates the substrate and the tip portion physically by means of an external force or chemically by means of a chemical material.

A prepuce extruding, cutting, hemostasis, and healing assembly using ultrasonic wave. Ultrasonic wave is applied in extruding, cutting, hemostasis, and healing of prepuce at a conjunction of internal and external tissues of a distal part of a human body. The assembly includes an ultrasonic generating device, a transmission device and a circumcision device. The ultrasonic generating device is used for generating ultrasonic waves, is connected to the transmission device and can send the ultrasonic waves to the transmission device. The transmission device is connected to the circumcision device and can send the ultrasonic waves to the circumcision device. The circumcision device is used for extruding and cutting a prepuce and/or performing hemostasis and/or healing of wounds. In this way, circumcision can be completed within just several seconds, and immediate healing can be achieved, preventing bleeding during and after a surgery.

Left atrial appendage (LAA) occlusion device including a membrane, a plurality of fixation splines and a deployment hub, the plurality of fixation splines for affixing the LAA occlusion device to an ostium of the LAA, the deployment hub being positioned in the membrane, the deployment hub including a threaded aperture and a one-way valve, for enabling a toxin to be entered into the LAA through the deployment hub.

A system for controlled sympathectomy procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. An implantable device for monitoring and/or performing a neuromodulation procedure is disclosed.

An injection pen to deliver a predefined dose of substance according to a prescribed schedule is disclosed. The injection pen includes a first portion having a medicinal chamber and a removable cover. The medicinal chamber is coupled to a piston on one end and attachable to an injection needle on an opposite end. The removable cover includes a solution dispenser. The injection pen includes a second portion couplable to the first portion. The second portion includes an actuator coupled to the piston for actuating the piston in an injection. The actuator may be controlled by an electronic circuit board embedded within the injection pen to regulate the delivery of a substance in the medicinal chamber based on a prescribed dose and injection schedule.

Disclosed is a method of treating microbial infections and their associated complications in humans. The method includes administering to a patient, a composition of dextrose and ethanol. The composition can be administered in the form of an infusion. For patients suffering from respiratory complications, the disclosed method also provides for enhancing oxygen uptake by lungs and reducing oxygen resistance through the administration of air having helium gas and excited oxygen atoms.