The exemplary embodiments may detect compression of a biological sensor and/or biological tissue of the user and may prompt or take corrective action to address the compression. A compression sensor may be provided to sense compression of the biological sensor and/or biological tissue of the user. Sensor data from the compression sensor may be processed to detect the compression. The detection of the compression may trigger corrective action. The corrective action may include an alert to alert the user to suggest a change in position or body orientation so as to alleviate the compression. The corrective action may include adjusting the biological sensor data to compensate for the compression or may include adjusting the quantity or rate of medicament delivered to a user to compensate for the compression. In some exemplary embodiments a data logger is provided to work with the biological sensor. The data logger may automatically log compression sensor data and biological sensor data.

Disclosed are a system, techniques and processes for monitoring and modifying a drug treatment regimen when a user partakes in a ketogenic diet. The disclosed system obtains ketone level measurements of a user and indicates a user's adherence to the ketogenic diet as well as modifying a user's total daily dosage of a drug based on the user's following the ketogenic diet.

A glucose level control system can intermittently receive alarm data corresponding to instances where an alarm was triggered and receive a request for the remote support system to contact the user. The system can transmit the request to the remote support system and determine that at least one of a plurality of support system criteria are satisfied. The control system can automatically identify a category of concern related to the request and generate a report of usage based on the category of concern and on the alarm data. The control system may transmit the report of usage to a remote electronic device and determine a support resource configured to receive the report of usage associated with the glucose level control system. The control system can generate a connection alert that is configured to request contact with a support request interface operatively coupled to the ambulatory medicament pump.

The invention relates to a device for treating an individual suffering from cardiac or circulatory arrest or from a stroke, comprising a blood withdrawal device (BE) that is applied to the individual (P), an analysis unit (BA) which is directly or indirectly connected to the blood withdrawal device for detecting a blood analysis result (BAE) providing at least one characteristic of the blood, directly or indirectly connected to a blood return device (BR) that is applied to the individual (P) and is designed to deliver a substance to the individual via the return device (BR).

A system for adjusting blood glucose level including an insulin delivery device configured to release insulin into the body of a person, and an EEG monitor having an EEG sensing part including EEG electrodes. The EEG monitor can be arranged in the ear region of the person with the EEG sensing part arranged subcutaneously at the scalp or arranged in the ear canal. The EEG monitor includes an EEG signal processor arranged at the ear and adapted for identifying onset of hypoglycemia. The system further includes a wireless link between the EEG monitor and the insulin delivery device. The EEG monitor is configured to submit a warning signal to the insulin delivery device if an upcoming onset of hypoglycemia is identified. The warning message will cause the insulin delivery device to restrict insulin delivery for a predetermined time, and a warning is provided to the person or to a caregiver.

Described are peritoneal dialysis systems and methods that involve the use of crossflow filtration of a used dialysate withdrawn from the peritoneal space of a patient. The filtration forms a retentate containing amounts of an osmotic agent and a permeate containing amounts of water and nitrogen-containing waste products of the patient. The retentate, or a fraction thereof, can be returned to the peritoneal space of the patient to return osmotic agent to the patient. The permeate, or a fraction thereof, can be discarded to discard nitrogen-containing waste products of the patient.

A pen cap for a medication delivery pen includes a piston-style detector mechanism. The piston-style detector mechanism includes at least an inner shell having first open end through which the medication delivery pen can be inserted, a second end opposite the first end, a sidewall defined by an outer surface and an opposing inner surface, and a passageway extending from the outer surface to the inner surface. The sidewall extends between the first end and the second end thereby defining a pen-receiving cavity there between. The piston-style detector mechanism further includes at least one switch and a translatable shaft at least partially disposed in the passage. The translatable shaft includes a body that extends at least from a pen-interfacing portion in the pen-receiving cavity to a switch-interfacing portion thereof. The translatable shaft is oriented to travel from a first location to at least a second location during capping of a medical delivery pen into the inner shell to toggle the at least one switch.

Disclosed is a method of treating microbial infections and their associated complications in humans. The method includes administering to a patient, a composition of dextrose and ethanol. The composition can be administered in the form of an infusion. For patients suffering from respiratory complications, the disclosed method also provides for enhancing oxygen uptake by lungs and reducing oxygen resistance through the administration of air having helium gas and excited oxygen atoms.

A system for the delivery of insulin to a patient is provided. The systems and methods disclose include an insulin delivery device configured to deliver insulin to a patient in response to control signals. The system also includes a controller programmed to receive the sensor glucose measurement signal from the glucose sensor. The sensor glucose measurement signal received indicates a concentration of the real time glucose concentration in a bloodstream. The controller is further configured to enact an impeding glycemia protocol based on a zone model predictive control (MPC) algorithm in response to the real time glucose concentration. The impeding glycemia protocol includes in determining a relationship between predicted glucose concentrations, a rate of change of the predicted glucose concentrations, and a set of control parameters that determine insulin doses above and below a patient-specific basal rate.

The invention comprises a cardiovascular state monitoring apparatus and a method for operating a drug delivery system, comprising the steps of: (1) receiving to the cardiovascular state monitoring/drug delivery system a first time-varying cardiovascular input waveform from at least one of: a pulse oximeter and a blood pressure monitor; (2) operating on the time-varying cardiovascular input waveform to generate transient cardiovascular state information, comprising at least one of: a current left ventricle stroke volume, a current blood pressure, a current arterial compliance, and a current blood flow rate; and (3) directing the drug delivery system to deliver a drug based on the generated transient cardiovascular state information.