The present invention is a self-injection pen. The self-injection pen has a needle, a medication cartridge, and a pen body. The needle and the medication cartridge are standard commercially available components that are suitable for injecting a liquid medication into the subcutaneous tissue layer of a human or animal body. The medication cartridge has a dose adjustor, and the pen body has an outer casing, a dose adjustment dial and an injector button. The needle is secured to the medication cartridge and allows a liquid medication to flow from the medication cartridge into the body of the user. The dose adjustor controls the amount of liquid medication being administered from the medication cartridge.

The present disclosure relates to systems and methods for controlling physiological glucose concentrations in a patient using a closed loop artificial pancreas. The systems and methods may utilize a controller with control logic operative to execute a multi-model predictive controller algorithm to determine a medication dose to the patient.

The present disclosure relates to completely closed systems suitable for bio-processing of cellular samples, for example peripheral blood samples used for immunotherapy applications, and related methods of use. The systems are not open to the air, thus allowing for sterile sample processing and transfer of the sample throughout the entirety of bio-processing. Each component of the disclosed systems contains a unique identifier, allowing for traceability of the sample as it proceeds through the various steps involved in bio-processing. The identifier ultimately traces the sample back to the patient from which the sample was derived. Certain embodiments provide a unique freezing bag for long-term storage of cellular samples. The freezing bag has a unique identifier that allows for easy traceability and retrieval of a bio-archived sample and at least two ports, one for sample testing, another for sterile docking to a device that allows for delivery of its contents to a patient.

A medical liquid injection device is provided. The medical liquid injection device includes a base body, a needle assembly mounted on the base body, a reservoir fluidly connected to the needle assembly and having a guide groove on an inner surface, and a driving unit configured to move a plunger disposed inside the reservoir.

A pen cap for a medication delivery pen includes a piston-style detector mechanism. The piston-style detector mechanism includes at least an inner shell having first open end through which the medication delivery pen can be inserted, a second end opposite the first end, a sidewall defined by an outer surface and an opposing inner surface, and a passageway extending from the outer surface to the inner surface. The sidewall extends between the first end and the second end thereby defining a pen-receiving cavity there between. The piston-style detector mechanism further includes at least one switch and a translatable shaft at least partially disposed in the passage. The translatable shaft includes a body that extends at least from a pen-interfacing portion in the pen-receiving cavity to a switch-interfacing portion thereof. The translatable shaft is oriented to travel from a first location to at least a second location during capping of a medical delivery pen into the inner shell to toggle the at least one switch.

A skin patch drug infusion device is disclosed. The skin patch drug infusion device includes an infusion mechanism module, the infusion mechanism module includes an infusion module and a circuit module, the circuit module includes: a circuit board or a three-dimensional circuit coated on the surface of part components, for supplying power to specific units; a power supply, for supplying power to the infusion device; an elastic conductor, provided with at least a protrusion, for electrically connecting the power supply to the specific connection end on the circuit board or three-dimensional circuit; a control mechanism module, electrically connected with the infusion mechanism module; and an adhesive patch, for attaching the infusion mechanism module and the control mechanism module to the skin surface. The elastic conductor is provided with protrusions.

The invention relates to a device for treating an individual suffering from cardiac or circulatory arrest or from a stroke, comprising a blood withdrawal device (BE) that is applied to the individual (P), an analysis unit (BA) which is directly or indirectly connected to the blood withdrawal device for detecting a blood analysis result (BAE) providing at least one characteristic of the blood, directly or indirectly connected to a blood return device (BR) that is applied to the individual (P) and is designed to deliver a substance to the individual via the return device (BR).

Exemplary embodiments may provide an on-body medicament delivery system that provides basal delivery of a medicament to a type 2 diabetes patient and that automatically performs medicament titration for the patient. The medicament delivery system performs medicament titration based on glucose level readings for the patient. These glucose levels may be provided wirelessly from a glucose sensor, such as a continuous glucose monitor, or may be entered manually by the patient into a management device, such as a smartphone running an application that provides a user interface for the patient to enter the glucose level readings. The medicament delivery system adjusts the basal medicament delivery rate/dose based on the glucose level readings for the patient. The adjustments may be performed by a programmatic mechanism, such as by computer programming instructions executing on a processor.

Apparatus and methods for delivering medicament to a patient. The apparatus may include elements with different capacities to attenuate or absorb sterilizing radiation. The apparatus may include a medicament delivery assembly with interactive elements for dose-setting, priming and medicament ejection. The assembly may include a chamber housing a radiation-sensitive medicament present in the apparatus during sterilization by electron beam. The assembly may include an actuator chassis, a drive mechanism, a needle-priming mechanism and a fluid-displacement mechanism including a fluid-displacement member. The chassis may be fixed, relative to an outlet, to the chamber. The member may be slidingly and/or threadingly engaged with the chassis, and may be configured to move relative to the outlet to deliver the medicament through the outlet. Assembly elements may be nested coaxially and/or stacked axially. The assembly may include at least one hollow region. The hollow region may reduce beam attenuation or reduce radiation absorption.

An apparatus peritoneal dialysis (1) comprising an automated peritoneal dialysis cycler (3) programmed to run a treatment session including a plurality of cycles, each cycle including a fill phase, a dwell phase and a drain phase of a peritoneal cavity of a patient (P), the treatment session lasting at most 720 min; the cycler (3) has a patient line (54) in communication with the patient (P), a source (S) of treatment fluid which includes an osmotic agent, a pump (5) to circulate the treatment fluid and a control system (74) configured to drive the cycler (3) to deliver the treatment session. The control system (74) is programmed to run a fill phase of a first cycle delivering a first treatment fluid to the patient, the first treatment fluid having a first concentration of the osmotic agent; subsequently to the first cycle, to run a fill phase of a second cycle delivering a second treatment fluid to the patient, the second treatment fluid having a second concentration of the osmotic agent different from the concentration of the first treatment fluid; subsequently to the second cycle, to run a fill phase of a third cycle delivering a third treatment fluid to the patient, the third treatment fluid having a third concentration of the osmotic agent different from the concentration of the second treatment fluid. The second concentration of the osmotic agent is lower than the first concentration of the osmotic agent and the third concentration of osmotic agent is higher than the second concentration of osmotic agent.