Systems and methods for reducing vibrations perceived by a human due to an artificial heart valve include a vest that is wearable around a torso of the human, a plurality of sensors mounted to the vest, a plurality of vibration-generating actuators mounted to the vest, and a controller. The plurality of sensors detects vibrations in the human generated by the artificial heart valve. The controller is operable to receive signals representing the detected vibrations from the plurality of sensors, and is operable to produce anti-vibration signals that substantially attenuate the detected vibrations. A first sensor of the plurality of sensors is located near a first vibration-generating actuator of the plurality of vibration-generating actuators to form a sensor/actuator set. In the sensor/actuator set, the anti-vibration signals generated by the controller for the first vibration-generating actuator correspond to the vibrations detected by the first sensor.

A system is disclosed. The system includes a reservoir for containing a fluidic medium, the reservoir including a front surface, a resilient cylindrical flexure portion connected to the front surface, the resilient cylindrical flexure portion comprising an accordion-like structure that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, a central passageway within the resilient cylindrical flexure, and a collection chamber connected to the central passageway. Also, a system including a reservoir, a plunger head located within the reservoir, a plunger arm connected to the plunger head, a driving shaft connected to the plunger arm, and a motor connected to the driving shaft, the motor controllable to move the drive shaft in a first motion and a second motion so as to move the advance plunger head and retract the plunger head within the reservoir.

A system for measuring the vital parameters of low care patients is described. The system includes a connecting element for a nasal cannula or breathing mask for providing a fluidic connection with the patient and a flow and/or pressure sensor in fluidic connection with the nasal cannula or breathing mask, for sensing, when the nasal cannula or breathing mask is connected to the system, at least a negative pressure signal. The system also includes a processor configured for deriving, directly based on said at least a negative pressure signal, information related to the breathing cycle, and an output means configured for outputting at least one vital parameter of the patient, the outputting comprising outputting information related to the breathing cycle.

A respiratory assistance device 10 includes: a mask 13 having an expiratory hole 13a; an expiratory valve 15 provided in the mask 13, for opening and closing the expiratory hole 13a; and a control unit 17 for performing overall control on the entire device. The mask 13 and the expiratory valve 15 together form an opening and closing device. The expiratory valve 15 is deformable by deformation of a piezo element 15a. The expiratory valve 15 is disposed on an inner surface 13f so that a deformation direction thereof, i.e., a thickness direction thereof, extends along the inner surface 13f of the mask 13 and a side surface 15m slides along the inner surface 13f by the deformation thereof.

A mist inhaler device (200) for generating a mist including a therapeutic for inhalation by a user. The device includes a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.

The invention relates to an aerosol delivery device (A) comprising an aerosol generator for generating an aerosol in the aerosol delivery device (A). The aerosol generator comprises a membrane (1) and a vibrator (7) which is configured to vibrate a fluid (3) and to aerosolise the fluid (3) by the membrane (1). The aerosol delivery device (A) further comprises a fluid reservoir (2) for receiving the fluid (3) to be aerosolised, wherein the fluid reservoir (2) is arranged in fluid communication with the membrane (1). Moreover, the aerosol delivery device (A) comprises a controller (10) which is configured to operate the vibrator (7) so as to vibrate the fluid (3), a temperature sensor (13) which is configured to detect a temperature of the vibrator (7) and/or the membrane (1), and a detector (13a) which is configured to detect the presence of fluid (3) in contact with the membrane (1) and/or in the fluid reservoir (2) on the basis of the temperature of the vibrator (7) and/or the membrane (1) detected by the temperature sensor (13). Further, the invention relates to a method of operating such an aerosol delivery device (A).

Autonomously administering a pharmaceutical agent to an animal. A tag assembly is affixed to an animal. The tag assembly may be an ear tag, although other configurations can be used. The tag assembly has a reservoir that houses a pharmaceutical agent. An actuator and an application mechanism are provided. A control signal is generated responsive to an input, which may be from a sensor associated with the tag assembly or may be from an external circuit located apart from the tag assembly. Receipt of the control signal causes the actuator to apply a force to the reservoir, which in turn induces a flow of the pharmaceutical agent, via the application mechanism, to a body of the animal. The pharmaceutical agent may be topically or intravenously applied. The pharmaceutical may be an insecticide or some other agent. Multiple reservoirs can be provided to dispense the same or different pharmaceutical agents.

A fluid delivery system provides fluid, such as supplement oxygen, to a patient in response to inhalation. The fluid delivery system includes a valve assembly that is triggered by sensing onset of inspiration by measuring a change in temperature of air flow in a nasal or oral cannula, mask or helmet.

A fluid delivery system provides fluid, such as supplement oxygen, to a patient in response to inhalation. The fluid delivery system includes a valve assembly that is triggered by sensing onset of inspiration by measuring a change in temperature or fluid flow of air flow in a nasal or oral cannula, mask or helmet.