According to one implementation an apparatus for bacterially disinfecting a surface is provided. The apparatus includes a flexible body that contains therein at least one radially emitting optical fibers that is configured to emit bacterial disinfecting light. The radially emitting fibers having an axial and/or radial freedom of movement within a channel in which it is housed inside the flexible body such that when the flexible body changes shape the axial and/or radial freedom of movement reduces the amount of tensile stress applied along the length of the radially as compared to an amount of tensile stress that would otherwise be applied to the radially emitting fiber in an absence of the axial and/or radial freedom of movement of the radially emitting fiber inside the channel.

An implantable blood pump including a housing having an inlet cannula, a rotor disposed within the housing, the rotor in fluid communication with the inlet cannula, a stator disposed within the housing, the stator configured to rotate the rotor when a current is applied to the stator, and at least one ultraviolet light emitter disposed within the housing.

The present invention is directed to a system and method for photoeradication of microorganisms from a target. The method includes the step of obtaining test data for a plurality of experiments each of which comprises irradiating test microorganisms with a plurality of light pulses having a wavelength that ranges from 380 nm to 500 nm. The light pulses have a plurality of pulse parameters (peak irradiance, pulse duration, and off time between adjacent light pulses) and are provided at a radiant exposure that ranges from 0.5 J/cm.sup.2 to 60 J/cm.sup.2 during each of a plurality of irradiation sessions. The test data comprises a survival rate for the test microorganisms after irradiation with the light pulses. The method also includes the step of analyzing the test data to identify the pulse parameters for the light pulses and the radiant exposure for each of the irradiation sessions that result in a desired survival rate for the test microorganisms. The method further includes the step of irradiating the microorganisms of the target with light pulses having the identified pulse parameters at the identified radiant exposure for each of the irradiation sessions so as to photoeradicate all or a portion of the microorganisms.

Systems and methods for treating biologic fluids are disclosed. Some disclosed embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject, heat CSF to a target temperature, cool CSF to a target temperature, apply light treatment to CSF, separate cells via their dielectric properties, apply spiral and/or centrifugal separation, introduce additives to target particles, and/or apply combinations thereof. The method may include the steps of withdrawing fluid comprising CSF, treating the fluid, and returning a portion of the treated fluid to the subject. During operation of the system, various parameters may be modified, such as flow rate.

Self-puncturing liquid drug cartridges and an associated inhaler are used to deliver one or more separate doses of an aerosolized liquid drug. A cartridge includes a needle assembly coupled to a drug container. The needle assembly includes a hollow needle and is reconfigurable from a first configuration to a second configuration upon insertion of the cartridge into the inhaler. In the first configuration, the hollow needle does not extend into the container. In the second configuration, the hollow needle extends into the container. The inhaler includes an aerosol generator that includes a vibratable membrane that aerosolizes liquid drug ejected from the cartridge for inhalation by a patient.

By combining efficient manufacturing technology, design for user-centric comfort and accessibility with advanced automated operator control and operational features, the float tank methods and systems described herein provide clients with a personalized float experience, voice and non-tactile control interfacing, and float facility owners with highly profitable and reliable equipment.

An incentive spirometer medical device having a mouth piece protected by an enclosure when not in use and being able to be operated by one hand to open to access the mouth piece.

A device to be used to destroy cancerous cells comprises a modified syringe with an ultraviolet radiation source. A modified syringe comprises a hollow syringe barrel including a fluid chamber, a plunger movable on advanced and retracted position slidably disposed within a fluid chamber, an ultraviolet radiation source that is fixed longitudinally through hollow syringe barrel and a plunger.

An ultraviolet radiation source fixation seal including two apertures disposed within a fluid chamber to permit a photoactive agent to flow from its container into a fluid chamber through the two apertures. Then, a photoactive agent in a fluid chamber is activated with an ultraviolet radiation that is emitted from an ultraviolet radiation source before it is injected directly to a cancerous cells' location using a modified syringe which is acting as an ordinary syringe.

Systems and methods for treating biologic fluids are disclosed. Some disclosed embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject, heat CSF to a target temperature, cool CSF to a target temperature, apply light treatment to CSF, separate cells via their dielectric properties, apply spiral and/or centrifugal separation, introduce additives to target particles, and/or apply combinations thereof. The method may include the steps of withdrawing fluid comprising CSF, treating the fluid, and returning a portion of the treated fluid to the subject. During operation of the system, various parameters may be modified, such as flow rate.

A system to be used to treat Leukemia, comprises a device to power, control and monitor an ultraviolet radiation as well as to monitor a blood contactless conductivity; and a catheter assembly with an inner dialysis catheter, an ultraviolet radiation source and a differential coil sensor. The system is using wavelengths of ultraviolet radiation to destroy infectious microbes that are in the blood and that are inside circulating tumor cells directly and indirectly as well as to destroy infectious microbes at primary tumor location (bone marrow). This is done without withdrawing the blood out of the body. Furthermore, the system measures a blood conductivity to evaluate the treatment process in a real time during the operation.