According to one implementation an apparatus for bacterially disinfecting a surface is provided. The apparatus includes a flexible body that contains therein at least one radially emitting optical fibers that is configured to emit bacterial disinfecting light. The radially emitting fibers having an axial and/or radial freedom of movement within a channel in which it is housed inside the flexible body such that when the flexible body changes shape the axial and/or radial freedom of movement reduces the amount of tensile stress applied along the length of the radially as compared to an amount of tensile stress that would otherwise be applied to the radially emitting fiber in an absence of the axial and/or radial freedom of movement of the radially emitting fiber inside the channel.

A disinfection system is provided. The disinfection system may utilize ultraviolet light and/or ozone for disinfection of infected tissue. For example the system may involve an endoscopic ultraviolet light to disinfect lung tissue. In another aspect, the system may involve a ventilator which provides ozone in small doses to disinfect the tissue. Combinations and variations are further disclosed.

A device for capturing momentarily an exhaled breath of a COVID 19 patient containing active SARS-CoV-2 virions within an accessible compartment of said device and converting said active SARS-CoV-2 virions into far-UVC inactivated SARS-CoV-2 virions by exposure to an activated 222 nm far-UVC lamp mounted in said accessible compartment and with the next inhaled breath of said COVID 19 patient said far-UVC inactivated SARS-CoV-2 virions are positioned within the respiratory system ready to be captured by an antigen-presenting cells such as the Dendritic cells (DCs) which are antigen-presenting cells that capture, process, and present antigens to lymphocytes to initiate and regulate the adaptive immune response. Said far-UVC inactivated SARS-CoV-2 virions can be collected from said accessible compartment of said device and processed into viable vaccine that can be administered to front-line workers.

Miniaturized high-intensity shortwave UV airflow treatment system in a compact easy-to-wear and fully portable form factor. Practical, germicidal air treatment system may be worn by or be carried by a user to kill or deactivate germs, viruses or other pathogens, which are located in the air to be breathed by the user. Air being inhaled or exhaled by the user is exposed to Ultra-Violet C-band (UVC) radiation. This UVC radiation is lethal to undesirable germs, viruses and other pathogens. In this manner, pathogen-free air is being inhaled or exhaled by the user.

A portable device provides filtered air to the face of a user, and has a housing having an air outlet disposed to direct air toward a face of a user, a fan disposed inside the housing for urging air toward the air outlet, a filter member disposed in the air outlet, and an air inlet. A UV light source is provided inside the housing, for providing UV light to purify air moving inside said housing toward said filter member. A CO detector disk is mounted on an outside wall of the housing, for providing a visible color change when CO is detected. A pill box is mounted on an outside wall of the housing, as well as a holder for a personal medications log mounted, and a personal medications log insertable therein.

Systems and methods for cleaning and maintaining artificial airways sized for insertion within pediatric or neonatal patients (e.g., external diameters of less than 5 mm) are disclosed. The system includes a multi-port ventilator manifold configured to couple to a ventilation source, thereby forming a ventilator circuit with the patient. The manifold includes an occluder configured to advantageously reduce an amount of dead space in the manifold so as to prevent loss of positive end expiratory pressure of the ventilator circuit and reduce the likelihood of broncho-pulmonary dysplasia of the patient, or even premature death.

Described is a method and device for dilating a tubular anatomical structure. The device and method can be useful for extracting a blood clot in an artery of a mammal by concentrically irradiating an inner wall of the occluded artery using an ultraviolet (UV) laser beam delivered by an optical fiber having an external or inverted conical tip. Dilation results from photophysical production and release of nitric oxide from the cells lining the arterial wall when UV laser light is projected as a ring beam onto the inner arterial wall. This minimal contact persistent dilation system prepares the artery for safer mechanical extraction by thrombectomy, owing to decrease in friction and dissolution of chemical bonding.

Liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a container for storing the liquid drug, an end cap having an ejection opening, a filter element, and a piston that is repositionable relative to the container to selectively eject a volume of liquid drug from the ejection opening. The filter element filters the liquid drug prior to ejection from the ejection opening. The liquid drug cartridge can be coupled with an inhaler that includes an aerosol generator. The aerosol generator includes a vibratable membrane onto which the liquid drug is ejected. The liquid drug is aerosolized by the vibration of the membrane for inhalation by a user.

This disclosure relates to a system and method for disinfecting a conduit, such as a conduit for use in a continuous positive airway pressure (CPAP) system. An example system according to this disclosure includes a sheath a probe magnetically suspended within the sheath. The probe includes an ultraviolet light source configured to emit ultraviolet light. Further, the probe is spaced-apart from an inner dimension of the sheath to allow a conduit to pass between the probe and the sheath.

Systems and methods for performing online extracorporeal photopheresis of mononuclear cells are disclosed. During a mononuclear cell collection cycle, blood is removed from a source and separated into a plasma constituent, a mononuclear cell-containing layer, and red blood cells, followed by the collection of a pre-product including at least a portion of the mononuclear cell-containing layer and at least a portion of the separated red blood cells. The mononuclear cell collection cycle may be repeated, followed by the production of a single mononuclear cell product using the collected pre-product(s). The mononuclear cell product is irradiated using a fixed dose of light, such that the mononuclear cell product is produced so as to have a predetermined volume and a predetermined hematocrit, regardless of the number of pre-products used to produce the mononuclear cell product. Following irradiation, at least a portion of the irradiated mononuclear cell product is returned to the source.