Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

The invention concerns a reservoir (1) for storing a liquid medicament. The reservoir (1) comprises a flexible container (10) which includes one folding layer (12), wherein the folding layer (12) includes a seam (13) which provides for a sealing of the flexible container (1). The reservoir comprises a rigid part (20) which is connected to the flexible container (10) and which includes a support (25) extending into the flexible container (10) and which includes one or more ports (21, 22) providing fluidic access to the flexible container (10). The reservoir comprises a porous hydrophilic membrane (26) which is connected to the support (25) of the rigid part (20). The invention further concerns a method for producing of a reservoir (1). The method comprises: providing a flexible tube (30) and a movable opening device (40) located inside the flexible tube (30), moving (S1) the moveable opening device (40) inside the flexible tube (30) by a distance in a longitudinal direction of the flexible tube (30), providing a rigid part (20), and bonding (S2) the flexible tube (30) to the rigid part (20) and providing a folding layer (12) included in the flexible container (10).

The specification discloses a portable dialysis machine having a detachable controller unit and base unit with an improved reservoir heating system. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a reservoir with an internal pan and external pan, separated by a space that holds a heating element. The heating element is electrically coupled to electrical contacts attached to the external surface of the external pan.

A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.

The present application discloses novel systems for conducting the filtration of blood using manifolds. The manifolds integrate various sensors and have fluid pathways formed therein to direct fluids from various sources through the requisite blood filtration or ultrafiltration system steps.

Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.

Embodiments of the present disclosure include a dialysis system having a disposable cartridge which includes one or more flowpaths arranged on or within the cartridge.

The invention relates to an interchangeable insert (1) for an ophthalmological medical device (99) for aspiration of fluid, such as for discharging fluid as part of suction flushing during an ophthalmo-surgical intervention, such as a cataract operation. According to the invention, this occurs by means of a fluid region (10) for receiving the fluid to be suctioned and a negative pressure region (20), to which a negative pressure can be applied. The fluid region (10) and the negative pressure region (20) are hermetically separated from each other by an at least partially flexible membrane (13).

A protective headgear includes a main body (e.g., face mask) that is worn over the face. The main body has an inhalation port that is for fluid coupling to an inhalation gas source and at least one exhalation port. The headgear includes an HME unit that has an inhalation leg that is in fluid communication with the inhalation port and a top leg that is in fluid communication with the inhalation leg and the at least one exhalation port. The top leg has an open window formed therein. The HME unit further includes an HME membrane that is disposed within the top leg adjacent the open window such that the HME membrane completely covers the open window.

A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.