The disclosure provides a drug monitoring device assembled outside an intravenous infusion set for intravenous infusion, including a fastening assembly, a monitoring sensor mounted on the fastening assembly, and a monitoring module. The monitoring sensor includes at least one turbidity light transmitter for emitting first light beams and at least one light receiver. The first light beams change in directions when passing through the intravenous infusion set. The at least one light receiver generates a first sensing signal in response to receiving one of the first light beams. The monitoring module generates a turbidity warning message when a number of the first sensing signals received during an estimation time period is greater than a turbidity warning threshold.

Various systems and methods for detecting air in a chamber of an infusion system are disclosed. In one embodiment, a determination is made that air is contained in the chamber on the basis of a change in the average force exerted against the plunger utilizing a derivative spike for event detection and a systematic reduction in the average force to confirm the nature of the change. In another embodiment, a determination is made that the chamber contains air when a difference between the current force profile and a baseline force profile crosses a threshold. In an additional embodiment, a force profile is classified as being an air force profile or a liquid force profile based on extracted features of the force profile.

The present invention discloses a multifunctional negative pressure drainage system switchable between various modes, including continuous negative pressure, intermittent negative pressure, rinsing, drug administration, and drug administration loop, including a medical wound dressing, a waste fluid bottle, a vacuum pump, a draining tube A, an airway A, a draining tube B, a peristaltic pump, a draining tube C, an infusion bottle, a draining tube E, a control valve A, a control valve B, and a control valve F. The medical wound dressing, the draining tube B, the peristaltic pump, the draining tube C, and the infusion bottle are connected in turn. The medical wound dressing, the draining tube A, the waste fluid bottle, the airway A, and the vacuum pump are connected in turn. The draining tube E is connected between the draining tube C and the draining tube A. The control valve A is disposed on the draining tube A. The junction between the draining tube E and the draining tube A is located between the control valve A and the medical wound dressing. The control valve B is disposed on the draining tube C. The junction of the draining tube E and the draining tube C is located between the control valve B and the peristaltic pump. The control valve F is disposed on the draining tube E.

A fluid processing device includes a controller, a centrifuge configured to receive and rotate a continuous-flow centrifuge chamber, a pump system, an optical detection assembly, and a pressure sensor. The controller executes a priming procedure in which a priming fluid is conveyed into the centrifuge chamber while the chamber is being rotated by the centrifuge, which moves air out of the chamber via a low-g outlet conduit. Upon detecting priming fluid exiting the centrifuge chamber via the low-g outlet conduit, the chamber is rotated at a higher rate to attempt to move any remaining air out of the chamber via the low-g outlet conduit. The controller then determines, based on signals from the optical detection assembly and pressure sensor, whether there is any air remaining in the centrifuge chamber. If so, the rotational rate is alternately decreased and increased until all the air has been cleared from the centrifuge chamber.

Methods and systems for maintaining patient fluid balance during an extracorporeal cell treatment are disclosed. The method includes minimizing the amount of saline or other fluid that is returned to the donor. Saline used during priming of the fluid circuit may be used to increase the volume of the collected cells to arrive at a treatment-ready product with a suitable hematocrit.

Systems and methods are provided for improving the flow rate of plasma being removed from a blood separation chamber during a blood separation procedure. The system includes a blood separation chamber in which plasma is separated from cellular blood components and an outlet line for removing the separated plasma from the blood separation chamber. A primary optical sensor assembly is associated with the blood separation chamber to directly monitor the interior of the blood separation chamber. A secondary optical sensor assembly is associated with the outlet line to monitor the separated plasma in the outlet line, with each optical sensor assembly checking for the presence of cellular components in the separated plasma. If the primary optical sensor assembly detects such a condition while the secondary optical sensor assembly does not, then a controller may take steps to resolve the conflict and continue the procedure.

A blood purification apparatus which can perform actions and operations according to the final stage of blood-return. Accordingly, a blood purification apparatus comprising a blood circuit including an arterial blood circuit and a venous blood circuit for extracorporeally circulating blood of a patient from a tip end of the arterial blood circuit to a tip end of the venous blood circuit; a blood purification means arranged between the arterial blood circuit and the venous blood circuit of the blood circuit and purifying blood flowing through the blood circuit; a substitution solution supplying means for supplying substitution solution to the blood circuit; and performing blood-return by substituting the blood in the blood circuit with the substitution solution supplied from the substitution solution supplying means after the blood purification treatment wherein the blood purification apparatus comprises a detecting means arranged at predetermined positions in the arterial blood circuit and the venous blood circuit and detecting presence or absence or blood concentration of the blood flowing in the arterial blood circuit and the venous blood circuit at said predetermined positrons, and a recognition means for recognizing a final stage of blood-return which is a condition near the end of the substitution of blood with the substitution solution based on the presence or absence of the blood or blood concentration detected by the detecting means.

An injection device comprising: a housing arranged to contain a liquid medicament or a medicament cartridge; an electrical coil arranged around an inner surface or an outer surface of the housing; an electricity storage apparatus electrically connected to the electrical coil; and a magnet arranged to be movable axially within a defined space with respect to the electrical coil, such that electrical voltage is induced in the electrical coil and a current is generated to charge the electricity storage apparatus.

Methods are provided for identifying a disposable flow circuit in a blood processing system. At least a portion of the disposable flow circuit is positioned within a centrifuge that is rotatable about a rotational axis and has a high-G outer wall with a window facing radially away from the rotational axis. The disposable flow circuit is monitored through the window to detect the presence of an expected identification feature and/or an expected alignment feature. If the expected feature is detected, a blood separation procedure is initiated, with the procedure including monitoring the disposable flow circuit through the window to detect characteristics of a fluid within the disposable flow circuit. If the expected feature is not detected, an alarm condition is generated and initiation of the blood separation procedure is prevented.

An optical monitoring system is provided for use with a blood processing system. The system includes a light source configured to illuminate a disposable flow circuit received in a centrifuge and a light detector configured to receive an image of the disposable flow circuit. A controller combines two or more of the images received by the light detector to generate a two-dimensional output. The output is used to control the separation of blood within the disposable flow circuit. The monitoring system may also be used to verify that the disposable flow circuit is suitable for use with the centrifuge or that the disposable flow circuit is properly aligned within the centrifuge. The monitoring system may be positioned outside of the centrifuge bucket which receives the centrifuge.