An extracorporeal blood treatment apparatus comprises: a blood treatment device (2); an extracorporeal blood circuit comprising a blood withdrawal line (6) and a blood return line (7) coupled to the extracorporeal blood treatment device (2), wherein the blood return line (7) presents a heating zone (14) coupled or configured to be coupled to a blood warmer (15); a blood pump (6) configured to be coupled to a pump section of the blood withdrawal line (6); at least a post-infusion line (13, 13′) connected to the blood return line (7) upstream of the heating zone (14); an air trapping device (9) placed on the blood return line (7) upstream of the heating zone (14).

Methods of colon cleansing and/or inspection are described which safely maintain a colon in an uncollapsed state. Balanced replacement of a volume of fluid, gas and/or solids evacuated during cleansing of the colon is described. Replacement volume comprises, for example, cleansing fluid, jetting gas, and/or inflation gas. In some embodiments, balancing of evacuated and replacement volume is achieved under automatic control, based on monitored volume of material exchange, and/or measurement of resulting pressures.

A dressing for an internal cavity may include a connector, a negative pressure pathway layer, an instillation pathway layer, a negative pressure manifold, and an instillation manifold. The negative pressure manifold can be disposed within the negative pressure pathway layer and the instillation manifold can be disposed within the instillation pathway layer. A proximate end of the negative pressure manifold can be fluidly coupled with a first channel of the connector. The proximate end of the instillation manifold can be fluidly coupled with a second channel of the connector. The negative pressure pathway layer and the instillation pathway layer can be configured to cooperatively form an inner volume therebetween. The inner volume may be configured to receive a space filler. The negative pressure pathway layer, the instillation pathway layer, and the space filler can be collectively configured to be positioned within the internal cavity.

Infusion systems and methods for administering an infusion fluid into a patients anatomic space at a variable flow rate without flow control include an administration set having a flexible tube fluidically connected to a needle connector, the needle connector including a receiving end fluidically connected to flexible tube, and an administering end opposite the receiving end and fluidically connected with an infusion needle, and the infusion needle having an inside diameter of about 0.0104 inches to about 0.0135 inches and fluidically connected to the administering end of the flexible tubing to deliver the infusion fluid to the patients anatomic space at variable flow rates dependent upon the saturation of the infusion fluid at the patients injection site.

Systems and methods for opening the eustachian tubes of a subject are provided. Aspects of the systems include: a swallow inducer; a nasal passage seal; a pressure source configured to apply positive pressure to a sealed nasal passage; a sensor configured to detect a parameter indicative of a swallow resultant palate closure; and a controller operably coupled to the pressure source and the sensor, wherein the controller is configured to cause the pressure source to apply positive pressure to a sealed nasal passage upon detection by the sensor of the parameter indicative of a swallow resultant palate closure. Also provide are methods of using the systems to open eustachian tubes. The systems and methods find use in a variety of different applications, e.g., the treatment of a subject for Otitis Media with Effusion (OME).

A method and apparatus used to prevent brain death by use of rapid and safe cooling of the brain is disclosed. The cisterna magna is accessed through a patient's neck and cooled artificial cerebrospinal fluid (aCSF) is circulated about spaces within the brain and in a subarachnoid space surrounding the brain by entering the cisterna magna with an entry through the neck of the patient with a specially designed needle/cannula which allows the flow of cooled aCSF about the brain. aCSF exits from an opening in the skull where a temperature/pressure sensor is placed. Data is sent to a computer-controlled motorized system that pumps cooled aCSF to the needle/cannula placed in the cisterna magna. The pumping of aCSF is controlled to maintain a predetermined temperature and/or pressure of the exiting aCSF.

The invention relates to a system for dialysis, comprising a housing comprising a flow path along which dialysate passes between a subject and a dialysate reservoir; a pump arranged to drive dialysate along the flow path; a sensing system arranged in the housing configured to sense one or more characteristics of the dialysate to produce an output; and a processor configured to observe said output to determine whether to switch on or off the pump such as based on pressure of the dialysate is above a predetermined value or a flow rate of the dialysate determined by the sensing system is zero. In a preferred embodiment, the one or more characteristics comprise at least one of turbidity, pressure and colour of the dialysate and the sensing system includes an optical sensor, a turbidity sensor and a pressure sensor.

A fluid management system may include an inflow pump providing a fluid inflow to a medical device, at least one pressure sensor, and a controller configured to receive pressure signals from the at least one pressure sensor, the pressure signals corresponding to a system pressure within the fluid management system. The controller may be configured to detect which one of a plurality of medical devices is fluidly connected to the inflow pump based on the pressure signals from the at least one pressure sensor and an rpm of the inflow pump.

The disclosed systems and methods are configurable central nervous system (CNS) delivery solutions for therapeutics, such as genetic medicines. The systems and methods first infuse a therapeutic bolus within intrathecal space and subsequently infuse a flush fluid to move the therapeutic bolus rostrally toward a target area and achieve a desired spread in the spine and/or brain. The second location can be at a location caudal to the delivery location of the therapeutic bolus.

An air conduit for a respiratory therapy device comprises a first end, a second end, and a tube portion, wherein the tube portion comprises a tube wall and an auxiliary structure, such as a rib. The air conduit may deliver a flow of air from a respiratory therapy device or a humidifier to a patient interface. The air conduit may comprise a plurality of auxiliary structures, some of which may consist of a polymeric material, and some of which may comprise a polymeric material and an electrical conductor. An auxiliary structure may be a helical rib extending across a length of the tube portion.