A display system for displaying digital content includes one or more LED-based lighting channels adapted to generate a first light output in a first operational mode at a first circadian stimulating energy (CSE), and a second light output in a second operational mode, the second light output associated with a second CSE, and a long red near infrared energy (LRNE) output in a third operating mode.

A method of providing a breath to a human patient. The patient has a patient connection connected, by a patient circuit, to a ventilator having a first ventilator connection and a different second ventilator connection. Each of the first and second ventilator connections are in fluid communication with the patient circuit. The method includes identifying, with the ventilator, initiation of an inspiratory phase of the breath, delivering a bolus of oxygen to the first ventilator connection before or during the inspiratory phase, and delivering breathing gases comprising air to the second ventilator connection during the inspiratory phase. The ventilator isolates the bolus of oxygen delivered to the first ventilator connection from the breathing gases delivered to the second ventilator connection.

Insufflation systems may provide a continuous flow of insufflation gas to a body cavity. The continuous flow may be directed over the lens of an endoscope received within a cannula to form a protective envelope around the lens and improve visibility. The continuous flow may be supplied by a pressurized gas source. The continuous flow line may be assembled in parallel to an insufflation line running through a standard insufflator configured to provide non-continuous gas flow to the body cavity. The lines may converge upstream of or at the cannula or the insufflation flow may be provided to a separate cannula. Continuous gas flow may be provided by recirculating gas from the body cavity through the cannula Continuous gas flow may be provided by storing gas from the non-continuous insufflation flow in an accumulator and releasing the gas during off phases of the insufflation flow.

Provided is a system comprising a plurality of inhalers that each include a processor configured to determine a value of a usage parameter relating to use of the respective first inhaler, encrypt data based on the value, and transmit the encrypted data. At least two of the inhalers include different medicament, such as a rescue medicament and a maintenance medicament. The system includes an external device that includes a processor configured to distinguish between the encrypted data of each respective inhaler, determine respective usage information relating to each of the distinct types of medicament based on the respective encrypted data, and control a user interface (e.g., of the external device) to communicate the usage information related to each inhaler and/or each respective type of medicament.

The present invention provides systems and methods for management and orchestration of a fleet of remote Internet-of-Things (IoT) devices. The present invention includes a platform for onboarding, provisioning, and managing remote IoT devices throughout their lifetime. The platform includes portals for manufacturers, vendors, and consumers to access device data and sensor data collected by the devices. The data collected by the portal is used to control the fleet of remote IoT devices as well as make recommendations, e.g., for sleep promotion and stress reduction.

An infusion pump system is disclosed. The infusion pump system includes an infusion pump and a controller device in wireless communication with the infusion pump, wherein the controller including instructions for controlling the infusion pump, wherein the instructions may be synchronized with a secure web portal.

A passive valve for use as a fixed leak valve. The valve includes a body having an internal chamber, first and second body ports in fluid communication with the chamber with the first port configured for fluid communication with a patient connection and the second body port configured for fluid communication with a ventilator, a body passageway in fluid communication with the chamber and with ambient air exterior of the body, and a check valve seal positioned to seal the body passageway to permit the flow of gas within the chamber through the body passageway to the exterior of the body and to prevent the flow of ambient air exterior of the body through the body passageway into the chamber. In alternative embodiments, the valve is incorporated into the patient connection or constructed as a separate part connectable to the patient connection.

A novel vaporizer device is disclosed having an elongated base extending from a first end to a second end with a mouthpiece formed proximate at the second end of the base, the mouthpiece comprising an inhalation aperture. An air intake manifold is provided with an ambient air input port disposed between a first manifold end and a second manifold end. A fluid path is formed between the first manifold end and the second manifold end the fluid flow path comprising an upstream input port in fluid communication with at least a first absolute barometric pressure sensor and in some embodiments a downstream input port in fluid communication with a second absolute barometric pressure sensor. The absolute pressure sensor for providing an absolute pressure signal to a control circuit for applying power to a heating assembly for heating a vaporizable material in dependence upon the received at least a pressure signal.

Provided is a system (10) for determining a probability of a CORD exacerbation in a subject. The system comprises a first inhaler (100) for delivering a rescue medicament to the subject. The rescue medicament may be suitable for treating the subject's acute respiratory disease, for example by effecting rapid dilation of the bronchi and bronchioles upon inhalation of the medicament. The first inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue and/or routine inhalations. The processor then determines, using a weighted model, the probability of the CORD exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the parameters are more significant in the probability determination than the number of rescue inhalations. Further provided is a method for determining the probability of a COPD exacerbation in a subject, which method employs the weighted model.

A respiratory pressure therapy (RPT) system may include a housing portion forming a plenum chamber pressurizable to a therapeutic pressure; a seal-forming structure constructed and arranged to with a region of the patients face; a positioning and stabilising structure constructed and arranged to provide an elastic force to hold the seal-forming structure in a therapeutically effective position on the patients head; a blower configured to pressurize the plenum chamber to the therapeutic pressure; a vent assembly configured to discharge gas from a plenum chamber to atmosphere; a sensor port positioned downstream of the vent assembly such that the sensor port is in pneumatic communication with the air within the plenum chamber in any position of the vent assembly; and a sensor in pneumatic communication with the air within the plenum chamber via the sensor port.