A clotting agent delivery system comprises a frame, a passageway extending along the frame, a discharge opening connected to the passageway, a clotting agent reservoir fluidly connected to the passageway to hold a clotting agent substance, a valve in the passageway to control flow of the substance through the passageway, and an actuator to allow propellent to flow into the passageway, wherein the valve and clotting agent reservoir cooperate to provide clotting agent substance to the discharge opening at constant pressure using the propellant. A method for delivering a clotting agent comprises inserting a delivery catheter into an anatomic area, coupling a clotting agent delivery system to the delivery catheter, the clotting agent delivery system having a reservoir of a clotting agent, operating a valve to release propellant for propelling the clotting agent, and conveying the propellant and the clotting agent to the delivery catheter at a constant pressure.

A device is provided for delivering a predetermined volume of at least one substance within a body cavity of a subject. The device contains a) a capsule for containing the predetermined volume of substances; b) a delivery end, having at least one orifice of diameter D, for placement in proximity to the body cavity; c) a valve mechanically connectable to the capsule, having at least two configurations: (i) an active configuration in which the valve enables delivery of the substances; and (ii) an inactive configuration, in which the valve prevents delivery of the substances from the capsule to the body cavity; and d) a fluid tight chamber configured to contain predetermined volume V.sub.gas of pressurized gas at a predetermined pressure, P.sub.gas. The capsule further contains at least one mixing mechanism that mixes the substances and the pressurized gas after the valve is reconfigured to the active configuration.

An injection device is presented having an outer housing configured to receive a syringe, the syringe containing medicament, a movable stopper, and a needle. A plunger rod moves the stopper and a needle shield moves relative to the outer housing between a needle covering position and a needle exposing position, where the needle exposing position is axially rearward of the needle covering position. The needle shield is biased axially forwardly toward the needle covering position. A locking member is axially moveable in the outer housing from a first axial position to a second axial position in response to forward axial movement of the plunger rod. A locking sleeve is axially movable relative to the outer housing between a non-locking position and a locking position, the locking position being axially rearward of the non-locking position, in which axial movement of the locking sleeve is selectively limited by the locking member when in the second axial position.

A handheld therapeutic apparatus and method of treatment are disclosed. In one example, the apparatus includes a valve system, a detachable gas cartridge housing unit that houses a gas cartridge or gas delivery from an outside gas cylinder in fluid communication with said valve system, a detachable treatment receptacle for the delivery of gas therapies is in fluid communication with said valve system, and a detachable nozzle in fluid communication with said valve system.

An injection device comprises a needle holder that supports a needle, and a vial holder that supports a vial. A spring urges the needle holder to move towards the vial holder but that movement is restrained by a latch until the time of use. Releasing the latch primes the device by allowing the needle holder to move, whereby a proximal end of the needle pierces a septum of the vial. The latch is preferably released by rotating an actuator. The same rotation preferably frees the needle holder and vial to be advanced axially relative to the actuator, whereby a distal end of the needle can be introduced into the skin of a subject. Compressed air from a tank may be used to drive the discharge of the vial. The air tank preferably surrounds the vial and provides a broad proximal surface, against which manual pressure can be applied to the device.

Syringes are described herein. In certain embodiments, a syringe includes a syringe body, a movable plunger, and a biasing member. The syringe body defines a cavity and a port in fluid communication with the cavity. The movable plunger is disposed within the cavity. The plunger and cavity define a volume. The port is in fluid communication with the volume. The biasing member is coupled to the plunger. The biasing member is configured to urge the plunger toward the port to dispense a fluid stored within the volume at a desired rate.

A medical device including an application device with a first fluid path and a container movably attached to the application device. The container and the application device have a second fluid path therethrough, the container includes an inner chamber that is intermediate proximal and distal portions of the second fluid path, the inner chamber is fluidly isolated from the proximal portion of the second fluid path at a first position of the container, and the inner chamber is fluidly coupled to the proximal and distal portions of the second fluid path at a second position of the container. The first fluid path bypasses the container and the passage of fluid through the first fluid path is separately controllable from the passage of fluid through the second fluid path.

A beneficial agent dispensing device comprises a dispenser body comprising a pressure chamber and at least one dispensing port. A flexible primary container stores the beneficial agent contained within the body. The arrangement is such that pressure in the pressure chamber depress the flexible primary container to expel the beneficial agent through the dispensing port. The beneficial agent dispenser can be configured to deliver the beneficial agent intranasally.

The present disclosure relates to an improved implantable drug delivery device, method, and system that is powered by compression and expansion of an inert gas contained within a compressible bellows and surrounded by a biocompatible housing that forms a reservoir which is connected to restricted channel for flow rate control and further connected to a flexible reinforced catheter that delivers medicants from the reservoir to the intrathecal space or other desired bodily tissue.

A drug delivery device, in the form of an injector, may include one of a number of systems for limiting the delivery of a medical fluid or drug product in case of movement of (e.g., removal of) the injector relative to the patient as determined by a proximity sensor. The drug delivery system may in the alternative or in addition include systems for indicating the amount of medical fluid or drug product delivered (or not delivered) in case of movement of (e.g., removal of) the injector relative to the patient as determined by the proximity sensor. The injector may be, for example, an on-body injector or an hand-held autoinjector.