A method of delivering a substance in aerosol or powder form to the upper respiratory tract is provided. The substance is orally administered into the larynx, through the pharynx, and out from the nose while minimizing inhalation into the lungs, whereby deposition of particles in the upper respiratory tract is achieved with limited deposition in the trachea, lower airways and lungs. Also provided is an oral delivery device having a mouthpiece for oral inhalation of a flow of a substance into the upper respiratory tract and a flow restrictor for enabling arrestment of the flow minimizing inhalation into the trachea, lower airways and lungs, which provides for a deposition of particles in the upper respiratory tract with limited deposition in the trachea, lower airways and lungs. Also provided is an oral delivery device having a mouthpiece for admission of a flow of a substance into the upper respiratory tract and a flow generator for pressuring the substance into travel through the upper respiratory tract.

A device for delivering a predetermined amount of a substance within at least one body cavity of a subject, where the predetermined amount is at an effective amount for treatment of obesity or binge eating disorder. The device includes (a) A volume to contain the predetermined amount of the substance. (b) A delivery end placeable in proximity to the body cavity. The delivery end is in fluid communication with the volume and comprises at least one orifice. (c) A valve mechanically connected to the volume, with at least two configurations: (i) an active configuration configured to deliver the predetermined amount of the substance; and, (ii) an inactive configuration, in which the valve prevents delivery of the predetermined amount of the substance. (d) A fluid tight chamber configured to contain a predetermined volume of pressurized gas at a predetermined pressure.

The present invention is directed to an improved suction catheter that increases the effectiveness of clearing the airway by way of non-limiting example, reducing the need for separate suctioning and foreign body grasping instruments. The embodiments described herein provide medical personnel the ability to use one hand and catheter to selectively grasp an anatomically lodged foreign body while reducing the likelihood of lumen blockage and interruption of suction.

An apparatus includes a guide member, a handle assembly, a gripping assembly, and a grip adjustment assembly. The handle assembly extends proximally from the guide member. The handle assembly includes a first engagement feature. The gripping assembly includes a second engagement feature. The gripping assembly is configured to selectively transition between a locked configuration and a movable configuration. In the locked configuration, the first and second engagement features are configured to engage one another to prevent relative movement of the gripping assembly relative to the handle assembly. The grip adjustment assembly includes a cam feature disposed on at least one of the handle assembly or the gripping assembly. In the movable configuration, the cam feature of the grip adjustment assembly is configured to flex the second engagement feature away from the first engagement feature allowing the gripping assembly to move relative to the handle assembly.

A device adapted for maintaining an airway in a patient, the device comprising a mask, the mask adapted to form a seal around the laryngeal inlet when properly inserted into a patient and an airway tube for providing ventilation gases and/or anaesthetic gases through the mask and to the lungs of the patient when the device is properly inserted in a patient, wherein the airway tube has a first proximal opening and a second proximal opening.

An oropharyngeal glove (OPG) is provided for use in a rigid or flexible bronchoscopy procedure and for anesthesia recovery. Portions of the OPG conform to portions of the patient's mouth and throat. During a bronchoscopy procedure, the bronchoscope tube passes through an opening in a proximal end of the OPG, through the OPG and through an opening in a distal end of the OPG into the patient's trachea. A protective lining of the OPG protects the patient's mouth, throat and vocal cords from being damaged by the bronchoscope tube. A tubular extension disposed on the proximal end of the OPG provides the opening through which the bronchoscope tube first passes. Post procedure, the tubular extension can act as an airway device that connects to a ventilator machine to deliver air to the patient, thereby obviating the need to install a separate airway device to ventilate the patient during anesthesia recovery.

Embodiments of the application involve a formulation of Fluticasone Propionate in the form of a suspension, gel or dry powder comprising Fluticasone Propionate, Fluticasone Furoate, Micronized Fluticasone Propionate or Micronized Fluticasone Furoate or other corticosteroids. Additional pharmaceutical components of the formulation may allow for the adherence and duration of the active ingredient to the inflamed esophageal tissues. The resulting medication formulation is then targeted with a drug delivery device and applied directly to the oropharynx bypassing the oral cavity altogether. The medication then flows down the back of the throat to the esophagus. By passing the oral cavity prevents the corticosteroid drug from being absorbed into the bloodstream through oral cavity tissues, helping to prevent harmful side effects. Additional side effects are avoided by using the medication Fluticasone, which exhibits exceptionally low gastrointestinal absorption.

A composition of food or therapeutic and other substances for administration as a cloud of droplets, the cloud comprising readily-soluble droplets having a median size range of approximately 3 microns to approximately 20 microns, or 5 microns to 10 microns, or 6 microns to 10 microns, for introduction to an animal via an ortho-nasal or retro-nasal route. Agonists or antagonists may include one or more of the following: sodium iodide, sodium chloride, magnesium chloride, capsaicin, piperine, linalool, ground cinnamon, a cannabinoid, pimento, onion, clove, thyme, ginger, menthol, or TRPV antagonists, and chocolate, Irish cream, caramel, lemon, lime, mango, raspberry, watermelon, blueberry, strawberry, mint, popcorn, meat, Resolvin D2 or nicotine. Devices for delivering compositions as an aerosol are described.

Methods and devices for delivering one or more substances within at least one body cavity are provided. The device includes at least one nosepiece including at least one capsule having a volume V.sub.sub of the substances; at least one base in communication with the nosepiece, the base including at least one chamber configured to confine pressurized fluid at volume V.sub.PF and pressure P.sub.PF; and at least one hollow puncturing member. The hollow puncturing member includes at least one end in fluid communication with the nosepiece and a second end in fluid communication with the base. The first and second ends are fluidly interconnected by a hollow tube. The fluid inlet port of the capsule is configured in terms of size and shape to interface in a sealable manner with the one end of the at least one puncturing member.

The present invention discloses a four-way complete cleansing system for the entire upper respiratory tract (upper airway) and the process of how to use this advanced system to perform a complete cleansing of the upper airway of a human. The device is equipped with two one-way valves and at least two exchangeable tips for an effective upper airway cleansing. The composition of the cleansing solution comprises a chemical compound or an herb extract or the combination having at least one of the cleansing activities against viruses, bacteria, fungi, inflammatory factors, allergens, and promoting membrane healing or immunomodulating, for the treatment and prevention of a respiratory tract disease of a human. The present invention also provides a process for cleansing the hard-to-reach upper respiratory tract, such as sinus, of a mammal to reduce the load of the pathogen, to reduce the amount of inflammatory mediators, to heal pathological changes, and collectively to treat a disease of a mammal, such as nasal allergy or the common cold. This invention also provides a new method of treating a variety of human respiratory tract diseases without adverse effects.