A device for introducing material into a body cavity is shown. The device includes a catheter with a distal tip. A first lumen extends through the catheter. The catheter is configured to faun a mist from liquid passed through the first lumen, for example including a misting nozzle in fluid communication with the first lumen and configured to provide a mist from a flow of liquid through the first lumen. An inflatable balloon may be included on the catheter to allow the user to isolate the portion of the body in which the material is introduced. Additional described features can provide for controlled deflection of a distal region of the catheter, guidewire or guide loop tool lumens, misting nozzles on the catheter, and delivery apparatuses including the catheter devices coupled to endoscopes such as bronchoscopes. Methods of use of the catheter devices and delivery apparatuses are also described.

Compositions, materials, devices and methods are disclosed for the use of decellularized avian lung scaffolds for potential xenotransplantation and other uses including use as novel lung assist or bridge-to-transplant devices and as potential alternatives to current ECMO devices and technologies. Decellularization of an avian lung and recellularization with human lung cells is described.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

This invention relates to nebulizers, which are machines that change a liquid form to a mist consisting of micron sized droplets. More specifically the invention relates to liquid medicament nebulizers, for example for delivering a mist of medicament to eyes, nasal passages, and lungs. A housing has a form which rolls to house first and second reservoirs, an expansion chamber, and a vibration element. The housing has a center of mass which urges the nebulizer to roll toward a storage position where the liquid drains from the first reservoir through the drain passage to the second reservoir.

The embodied invention is a new inspiration/expiration ventilator flow design, with a constant inspiration flow and intermittent-concurrent expiratory flow based on lung pressure setpoints. This mode is possible by using a new dual lumen tube inserted into a patient Trachea. Additionally, the control provides support for patient initiated breathing which is initiated by a lung pressure drop. This control provides continuous and gentle recruitment of lung alveoli.

Ternary phased medical procedural process for fracturing and cleansing a viral pathogen from a pulmonary system, (FLiM) of a patient that has tested positive for a pulmonary viral pathogen, and the viral pathogen's constitution consisting of a lipid membrane, for example, the viral pathogen Covid19, by means of a FLiM performed by a Medical Professional (MP), utilizing potential permutations, MD/S (nPk) x ELT (nPk) and of at least: a continuous aqueous suspension, herein understood as; a Microcrystalline Castile Colloid (MCC), at least one medical device, a medically equipped operating theater, at least one computer and a network, and comprised of at least the steps of: diagnosing, determining, prepping, performing, diagnosing and following-up on the patient for FLiM medical procedure process.

Methods, devices, and systems for obtaining a navigating to a targeted biopsy region are disclosed. An example device for navigating to a targeted biopsy region may include an elongate shaft having a proximal end, a distal end, an inflation lumen, and a vacuum lumen. An inflatable balloon may be positioned proximal to the distal end of the elongate shaft. The device may further include an ultrasound transducer positioned adjacent to the distal end of the elongate shaft and a power and control unit in electrical communication with the ultrasound transducer. A vacuum source may be in fluid communication with the vacuum lumen.

The method and system according to preferred embodiments of the present invention allows an effective delivery of aerosolized medicament (e.g., a surfactant) to the patient's lungs. According to a preferred embodiment, the method of the present invention provides an efficient delivery of the aerosol medicament (possibly breath synchronized). A glass vial in which medicaments are usually stored and shipped is used directly as a component of the system. Its function in the system is that of an intermittently pressurized chamber that can inject the surfactant into the catheter of the atomizer device. According to a preferred embodiment the delivery can be done in phase with the beginning of each inspiration. The main elements of the system are: a source of compressed gas, the already mentioned medicament vial, a catheter, and optionally means to detect the breathing pattern and a control unit.

The hiccup relieving apparatus includes a tube with a first end having a mouthpiece, a second end for immersion in water or other potable liquid in a container, and an obstruction in the tube between the first end and the second end. The obstruction requires an adult user, using the mouthpiece, to produce a threshold suction of at least 20 cm of water before water can flow from the water in the water container, through the tube, through the mouthpiece, and to the user. The obstruction can take the form of a threshold valve in the tube, a sized orifice in the immersed end of the tube, or a wad of cellulosic material in the tube.