Apparatus and methods are described for improving renal function of a patient, including mechanically occluding the patient's inferior vena cava downstream of the renal vein ostium to form an upstream region and a downstream region of the inferior vena cava, and mechanically pumping blood through the inferior vena cava from the upstream region to a discharge location in the downstream region while the inferior vena cava is occluded, wherein the blood remains in the inferior vena cava while being mechanically pumped. Other applications are also described.

Methods, systems, and apparatuses for integrating medical device data are disclosed. In an example embodiment, an integration engine receives infusion therapy progress data from an infusion pump and renal failure therapy progress data from a renal failure therapy machine. The integration engine determines a plurality of different types of infusion parameters, determines a plurality of different types of renal failure therapy parameters, and causes a combination user interface to display the plurality of infusion parameters, the plurality of renal failure therapy parameters, and mathematical operations for selection by an operator. The integration engine enables the operator to create derivative data by receiving a selection of an infusion parameter, a renal failure therapy parameter, and a mathematical operation. The integration engine then causes the combination user interface to display the derivative data in conjunction with the infusion therapy progress data and the renal failure therapy progress data.

The present disclosure is directed to a medical device. Systems and methods are provided for utilizing a laser to break a kidney stones into smaller fragments and/or dust, and removing particles, stone fragments and/or stone dust from a patient. The medical device may include a delivery device including a tube, and an elongate member having a distal end, a proximal end, and a lumen extending between the proximal end and the distal end, wherein the elongate member is configured to move axially relative to the tube and apply suction through the distal end.

A whole-body hyperthermia system for raising the body temperature of the entire body of an individual to a predetermined target temperature and for stabilizing the body temperature at the target temperature comprises an apparatus means for raising the body temperature at a rate of at least 1 C./hour, and at least a second thermal means for further adjusting the body temperature to the target temperature Tb. The second thermal means comprises a fluid circuit, which is at least partially within the individual, and a fluid, heated by a heat exchanger to a set temperature is circulated through the fluid circuit.

Described herein are devices, systems, and methods used to assess an organ or organ system and determine a course of treatment for said organ, organ system, and/or patient.

Kidney stone removal system is disclosed having components including a handle mechanism, a nozzle tip, and a guiding device. The handle mechanism employs a trigger that enables control of irrigation and vacuum/suction. Depression of a trigger in the trigger mechanism conveys status of vacuum/suction and irrigation to a user by providing increased resistance at different points of depression. When the trigger is in a home (undepressed) position, irrigation and vacuum/suction are turned off. When the trigger is in a fully depressed position, irrigation and vacuum/suction are turned on. When the trigger is in an intermediate position, irrigation may be turned on, while vacuum/suction remains turned off. The nozzle includes one or more irrigation ports positioned at a distal end of the nozzle and having an irrigation port departure angle of 30 to 60 degrees for directing irrigation fluid forward and laterally from the distal end of the nozzle. The guiding device is configured to be removably positioned in the nozzle for receiving a debris fragmentizing device, such as a laser device. The guiding device is configured to prevent an unintended movement of the fragmentizing device when the fragmentizing device is positioned in the nozzle while allowing fluid and debris to flow past the fragmentizing device and through a vacuum tube.

Apparatus and methods are described for improving renal function of a patient, including mechanically occluding the patient's inferior vena cava downstream of the renal vein ostium to form an upstream region and a downstream region of the inferior vena cava, and mechanically pumping blood through the inferior vena cava from the upstream region to a discharge location in the downstream region while the inferior vena cava is occluded, wherein the blood remains in the inferior vena cava while being mechanically pumped. Other applications are also described.

Certain aspects relate to percutaneous sheaths for medical procedures as well as to related systems and methods. For example, a system for performing a percutaneous assisted medical procedure can include a percutaneous sheath. The percutaneous sheath can include a first conduit for providing aspiration into the kidney and a second conduit for passing a catheter into the kidney. The system can also include an aspiration catheter configured to be inserted into the kidney through the second conduit of the percutaneous sheath. A fluidics system can include an irrigation source comprising a pump and an aspiration source comprising a vacuum. The irrigation source can be connected to a fluid inlet of the percutaneous sheath that is connected to the first conduit. The aspiration source can be connected to the aspiration catheter.

An implantable or wearable kidney enclosure that is cylindrical, ovoid, or otherwise non-angular e.g., not rectangular or cuboid), having a circular or oval hemofilter that provides a blood flow pattern from an internal, central artery source radially outwards. Due to the efficient flow of the circular filter design, the enclosure can be made in a cylindrical low profile shape, resulting in a compact enclosure highly suitable for implantable and wearable dialysis applications.

A ureteral catheter for placement in a kidney, renal pelvis, and/or in a ureter adjacent to the renal pelvis of a patient, includes: an elongated tube having a proximal end, a distal end, and a sidewall extending therebetween defining at least one drainage lumen extending through the tube, wherein a proximal portion of the elongated tube is essentially free of or free of openings; and an expandable retention portion which defines a three-dimensional shape positioned to maintain fluid flow from the kidney through at least the distal end of the tube and inhibit tissue of the ureter or renal pelvis from occluding the at least one drainage lumen at the distal end of the elongated tube upon application of negative pressure through the drainage lumen, wherein the three-dimensional space defined by the expandable retention portion encloses at least a portion of the distal end of the elongated tube.