A percutaneous nephrolithotomy (PCNL) needle may include a cannula including a shaft and a cannula hub coupled to a proximal end of the cannula shaft. A depth guide may be disposed on an outer surface of the cannula shaft. A stylet may be disposable within the cannula lumen and may include a tapered point at a distal end of the stylet and a stylet hub coupled to a proximal end of the stylet that is configured to be releasably securable to the cannula hub. An adjustable depth stop may be releasably securable to the cannula shaft at a desired position relative to the depth guide, the adjustable depth guide capable of being manipulated between an adjustment configuration in which the adjustable depth guide is moveable relative to the cannula shaft and a secured configuration in which the adjustable depth guide is secured relative to the cannula shaft.

A percutaneous urinary catheter configured to be deployed in a urinary tract, including: (a) a proximal portion; and (b) a distal portion including a retention portion configured to be deployed in a kidney and/or a renal pelvis, the retention portion including one or more drainage holes leading to one or more lumen(s) within the proximal portion, wherein the retention portion, when deployed, defines a three-dimensional shape sized and positioned to maintain patency of fluid flow between the kidney and/or renal pelvis and a proximal end of the catheter by inhibiting mucosal tissue from appreciably occluding the one or more drainage holes when negative pressure is applied through the catheter.

A percutaneous urinary catheter configured to be deployed in a urinary tract, including: (a) a proximal portion; and (b) a distal portion including a retention portion configured to be deployed in a kidney and/or a renal pelvis, the retention portion including one or more drainage holes leading to one or more lumen(s) within the proximal portion, wherein the retention portion, when deployed, defines a three-dimensional shape sized and positioned to maintain patency of fluid flow between the kidney and/or renal pelvis and a proximal end of the catheter by inhibiting mucosal tissue from appreciably occluding the one or more drainage holes when negative pressure is applied through the catheter.

A method involves positioning a housing in an ureteral access sheath that is positioned in a lumen in a living body, moving the housing toward calculus located in the ureteral access sheath, positioning the housing in the ureteral access sheath adjacent the calculus in the ureteral access sheath, drawing the calculus in the ureteral access sheath through the inlet and into the housing by suction in the interior of the housing, and removing the housing from the ureteral access sheath while the calculus remains in the housing.

A system for retrieving material from a cavity in a patient may include a tube having a proximal end and a distal end, the scope configured to be inserted into the cavity, and a filter assembly disposed between the tube and a vacuum source configured to apply negative pressure through the tube to cause the material to flow through the tube from the distal end to the proximal end, the filter assembly including a filter configured to trap the material in the filter assembly, and allow liquid and gases to pass through the filter assembly.

Several embodiments of a catheter are described, having a balloon configured to slowly inflate and then quickly deflate to create an area of low pressure in the vessels. The balloon can be cycled near the vessels of the kidneys, thereby helping to draw out blood from the kidneys and enhance fluid processing to the bladder.

A negative pressure therapy system is provided for inducing negative pressure in a portion of a urinary tract, the system including: (a) at least one ureteral catheter configured to be positioned within a ureter and/or kidney; (b) one or more sensor(s) configured to determine information about at least one of blood composition, blood flow, respiration, heart rate, glucose, protein, or creatinine; and (c) a controller configured to increase urine production by adjusting one or more operating parameters of a negative pressure source for inducing negative pressure through the at least one ureteral catheter into the urinary tract, based at least in part upon the information determined by the one or more sensor(s).

Disclosed is a medical device or system comprising an elongate member having a distal end and a proximal end; an inflow lumen disposed within the elongate member, the inflow lumen having a proximal end, a distal end and a slanting exit opening at the distal end of the inflow lumen; and an outflow lumen also disposed within the elongate member, the outflow lumen having a proximal end, a distal end and a slanting receiving opening at the distal end of the outflow lumen. The disclosed medical device or system further comprises pressure sensors disposed at the distal end of the elongate member. Also disclosed is a method of employing the above disclosed device or variations thereof to remove small stones or small stone fragments from within the body's lumen or internal organ of a subject.

The present disclosure is directed to a medical device. Systems and methods are provided for utilizing a laser to break a kidney stones into smaller fragments and/or dust, and removing particles, stone fragments and/or stone dust from a patient. The medical device may include a delivery device including a tube, and an elongate member having a distal end, a proximal end, and a lumen extending between the proximal end and the distal end, wherein the elongate member is configured to move axially relative to the tube and apply suction through the distal end.

In accordance with some configurations, systems and methods for guided removal from an in vivo subject are provided. In some configurations, a method for removing an object is provided. The method comprising, guiding a flexible tube through a passageway of an in vivo subject, wherein the flexible tube comprises at least a first passageway and a second passageway. Positioning a distal end of the first passageway in proximity to the object. Infusing liquid through the second passageway substantially continuously. Removing the object through the first passageway with at least a portion of the liquid while suction is not being provided.