A pump for inducing negative pressure in the ureter and/or kidney is provided. The pump is configured to be in communication with at least one lumen of at least one ureteral catheter and to draw fluid from the ureter and/or kidney into the at least one lumen of the at least one ureteral catheter for removal of the fluid from the ureter and/or kidney. The pump is configured to induce negative pressure ranging from about 0.1 mmHg to about 50 mmHg gauge pressure proximate to the pump inlet, and the pump is configured to have an accuracy of about 10 mmHg or less proximate to the pump inlet.

A urinary catheter includes a catheter tube with a lumen, a proximal end, a distal end and a balloon coupled to the proximal end. The balloon is configured to be positioned in an interior of a bladder. The proximal end is configured to provide flow of urine from the bladder through the catheter lumen bag collects urine from the bladder through the catheter lumen. The drainage bag has an inlet port for receiving urine and an outlet port for draining urine from the drainage bag. The urinary catheter tube includes the proximal end and the proximal end, with a plurality of urine draining holes that receive urine from the bladder and allow it to be transported to and though the urinary catheter tube. One or more sensors included in the urinary catheter and positioned to be in contact with patient's urine. An artificial intelligence engine is coupled to the one or more sensors to receive sensor data, and make recommendations relative to a health of a patient.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

A catheterization tray includes a sterile side configured to enable a user to carry out sterile steps of a catheterization procedure in a sterile field and a set of sterile items positioned in the sterile side of the catheterization tray. The catheterization tray further includes a non-sterile side configured to enable a user to carry out non-sterile steps of the catheterization procedure outside of the sterile field and a set of non-sterile items positioned in the non-sterile side of the catheterization tray. The catheterization tray further includes a partition extending between the sterile side and the non-sterile side from a first side wall of the catheterization tray to a second side wall of the catheterization tray to maintain sterility of the sterile side of the catheterization tray.

Implantable drug delivery devices include a housing having a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure, and a drug contained in the drug reservoir lumen, wherein the first wall structure is impermeable to the drug and the second wall structure is permeable to the drug. Methods of providing controlled release of drug to a patient include deploying a drug delivery device in the patient releasing a drug from the drug reservoir lumen via diffusion through the second wall structure.

Disclosed herein are systems, devices, and methods for the removal of objects from the body. The device may be a urethral catheter configured to aspirate kidney stones from the urinary tract through one or more aspiration ports at the distal face or along a lateral side of the catheter. The catheter may include one or more irrigation ports at the distal face or along the lateral side of the catheter for dislodging kidney stones. The device may be steerable. The spatial arrangement of the one or more irrigation ports with respect to the one or more aspiration ports may vary. The device may include an irrigation tube and/or a shield member configured to spatially confine the kidney stones adjacent the catheter. Various temporal patterns of aspiration and irrigation are disclosed for optimizing removal of kidney stones.

A urinary drainage system can include an air pressure apparatus with a connector having an elongate connector body. The connector includes a lumen having a larger proximal lumen diameter and a smaller distal lumen diameter. The system includes an air intake adapter having an elongate adapter body, including a proximal end having a proximal opening configured to be coupled to the distal end of the connector. The adapter can include an air intake port in fluid communication with the adapter lumen, the adapter lumen having a larger proximal lumen diameter and a smaller distal lumen diameter.

An ultrasound probe includes a shaft having a proximal end, a tip, and a length measured between the proximal end and the tip; a plurality of channels defined in the shaft including an ultrasound channel and a balloon channel; ultrasound transducer(s) disposed in the ultrasound channel; and an offset balloon attached to the shaft at a predetermined distance from the ultrasound transducer(s), the offset balloon fluidly coupled to the balloon channel. In an inflated state the offset balloon has an inflated size that is larger than a target anatomical opening such that an inflated offset balloon is configured to mechanically engage the target anatomical opening when the shaft is inserted or retracted with respect to the target anatomical opening. The ultrasound transducer(s) is/are aligned with respect to a target volume when the inflated offset balloon mechanically engages the target anatomical opening.

A cannula comprising a hollow tube made of a biocompatible, thermoplastic polymer, memory shape material, tipped with an injection needle or an electrode at it distal end, assumes desired shapes as it distally emerges from a lumen or channel of an instrument such as an introducer or endoscope. The desires shapes include a curvature conforming to an inverse tangent function. The cannula may be supplied alone, with or without an injection needle or electrode, and in a sterile pouch, for use with a device of a user's choice that has a suitable lumen or channel to guide the cannula, of the cannula may be used without such an instrument. The injection needle can be shorter than conventional to thereby inject medication only or primarily in submucosa and can be sharpened only or mostly at it distal end while the remaining portion of a bevel is not sharp, to thereby reduce the size of an opening the needle makes in tissue and helps keep the medication from leaking out of the injection site.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.