A generator includes a series-connected inductive energy store and a superfast drift step recovery diode, as well as a load connected in parallel to the drift step recovery diode and switches. The switches are arranged in series, and the inductive energy storage device is connected to the point of connection of the switches therebetween and adjusting the amplitude of the pulses on the load by changing the closing and opening times of the switches. The moment of closing of the second switch is in the time interval between the opening of the first switch and changing of the polarity of the current through the inductive storage, wherein the time of its opening is in the interval of time from the beginning of the pulse formation on the load until the next closure of the first switch.

An output signal driver includes a positive output node, a negative output node, a power supply input node, a power supply common node, a charging capacitor, a discharging capacitor, a current source, a current sink, a first switch, a second switch, and a controller. The charging capacitor is coupled to the power supply input node. The discharging capacitor is coupled to the negative output node. The current source is coupled between the power supply input node and the positive output node. The current sink is coupled between the positive output node and the power supply common node. The first switch is coupled in parallel with the current source. The second switch is coupled in parallel with the current sink. The controller is coupled to the current source, the current sink, the first switch, and the second switch to apply either complementary constant current pulses or complementary constant voltage pulses to the positive output node.

A high-power pulse generator (1), belonging to the LTD family, includes two series of power modules, one series of standard modules (3s) and one series of modified modules (3m), each including a switch (6s; 6m), provided with a trigger electrode (9s; 9m), positioned in series between two capacitors (4s; 4m), the modified modules being designed to produce a pulse at a frequency substantially three times the frequency of the standard modules, and a trigger device (13) designed to control the standard and modified switches (6s; 6m) via a single trigger signal applied to the trigger electrode (9s; 9m) of same. The trigger signal is applied to the switches through a trigger impedance (10m; 10s) that is different between the standard and modified modules, and the plateau slope of the generated pulse depends on the difference between the value of the standard impedance and that of the modified impedance.

A high-power pulse generator (1), belonging to the LTD family, includes two series of power modules, one series of standard modules (3s) and one series of modified modules (3m), each including a switch (6s; 6m), provided with a trigger electrode (9s; 9m), positioned in series between two capacitors (4s; 4m), the modified modules being designed to produce a pulse at a frequency substantially three times the frequency of the standard modules, and a trigger device (13) designed to control the standard and modified switches (6s; 6m) via a single trigger signal applied to the trigger electrode (9s; 9m) of same. The trigger signal is applied to the switches through a trigger impedance (10m; 10s) that is different between the standard and modified modules, and the plateau slope of the generated pulse depends on the difference between the value of the standard impedance and that of the modified impedance.

A high voltage power system is disclosed. In some embodiments, the high voltage power system includes a high voltage pulsing power supply; a transformer electrically coupled with the high voltage pulsing power supply; an output electrically coupled with the transformer and configured to output high voltage pulses with an amplitude greater than 1 kV and a frequency greater than 1 kHz; and a bias compensation circuit arranged in parallel with the output. In some embodiments, the bias compensation circuit can include a blocking diode; and a DC power supply arranged in series with the blocking diode.

Some embodiments of the invention include a pre-pulse switching system. The pre-pulsing switching system may include: a power source configured to provide a voltage greater than 100 V; a pre-pulse switch coupled with the power source and configured to provide a pre-pulse having a pulse width of T.sub.pp; and a main switch coupled with the power source and configured to provide a main pulse such that an output pulse comprises a single pulse with negligible ringing. The pre-pulse may be provided to a load by closing the pre-pulse switch while the main switch is open. The main pulse may be provided to the load by closing the main switch after a delay T.sub.delay after the pre-pulse switch has been opened.

A pharmaceutical composition is provided comprising a highly soluble arsenic carbonate and/or bicarbonate compound and which is useful in the treatment of a variety of cancers, including acute promyelocytic leukaemia. The arsenic carbonate and/or bicarbonate salt acts as a solid, and so orally deliverable, improved bioequivalent delivery form of arsenic trioxide IV solutions.

The present disclosure relates to a high voltage generator including multiple high voltage generating modules configured to provide a total voltage. Each of the multiple high voltage generating modules may be configured to receive a driving pulse and generate a voltage component of the total voltage according to the driving pulse. The multiple high voltage generating modules may be in a series connection. Time points when the multiple high voltage generating modules receive driving pulses may be different, and waveforms of the driving pulses may be the same.

Disclosed are a high-voltage pulse generator and a communication method therefor. The high-voltage pulse generator comprises a master controller and a sub-controller. Data transmitted between the master controller and the sub-controller at least comprise a first class of data and a second class of data, and, the second class of data at least comprise two types. The communication method comprises the following steps: during the present instance of transmitting a first class of data, transmitting partial types of a second class of data; during the next instance of transmitting the first class of data, transmitting other types of second class of data; and repeatedly executing the step until the transmission of all types of second class of data is completed. The present application ensures an increased real time performance in the transmission of the first class of data; moreover, controller pin resources occupied are reduced, costs are reduced, and the problem of data conflict is avoided.

Some embodiments include a nonlinear transmission line system comprising: a power supply providing voltages greater than 100 V; a high frequency switch electrically coupled with the power supply; a nonlinear transmission line electrically coupled with the switch; an antenna electrically coupled with the nonlinear transmission line; and an energy recovery circuit comprising a diode and an inductor electrically coupled with the power supply and the antenna.