An electrically-powered inhalation device for delivery of an aerosol to the oropharynx of a user comprises respective proximal and distal portions, the proximal portion including an inlet for a liquid, the distal portion including an aerosol outlet defining a mist-exiting location and a piezo assembly including an ultrasonically vibrable mesh membrane, for producing, upon electrical activation, a mist comprising droplets of the liquid, the mesh membrane defining a mist-generating location; and an intermediate portion disposed distally from the proximal portion and proximally from the distal portion, wherein the distal portion is dimensioned to vertically span the user's oral cavity from tongue to hard-palate when the user's lips and/or teeth are transversely engaged with the intermediate portion, so as to place the mist-exiting location in fluid communication with the user's oropharynx.

A capnography system (100, 400), comprising: a controller (110, 410) configured to obtain a sample gas flow from a physical interface (107) for a patient (101); determine a change in a characteristic of the sample gas flow during a sampling time interval; determine whether the change in the characteristic of the sample gas flow during the sampling time interval is equal to or greater than a corresponding threshold value; determine that supplemental oxygen is provided when it is determined that the change in the characteristic of the sample gas flow is equal to or greater than the threshold value; and determine that supplemental oxygen is not provided when it is determined that the change in the characteristic of the sample gas flow is less than the threshold value.

Detection of unintentional air leaks in a user interface (e.g., mask) of a respiratory therapy system (e.g., a positive air pressure device) is disclosed. One or more sensors (e.g., within a computing device, such as a smartphone) can be moved around relative to the user interface to determine a location and/or intensity of an air leak. The computing device can provide feedback regarding the location and/or intensity of the air leak to facilitate the user locating the air leak, and thus correcting the air leak. In some cases, augmented reality annotations can be overlaid on an image (e.g., live image) of the user wearing the user interface to identify the location of the air leak. The system can automatically detect the type of user interface being used and can provide tailored guidance for reducing the air leaks.

A gas analysis system includes a gas analyzer which analyzes a gas acquired from a living body and a liquid separator which is detachably attached to the gas analyzer, and which separates a liquid component from the gas. In the gas analysis system, the liquid separator includes a magnet, and the gas analyzer includes a magnetic sensor which detects magnetism generated by the magnet, and a determining section which, based on the magnetism detected by the magnetic sensor, determines that the liquid separator is attached to the gas analyzer.

Described are systems and methods for monitoring administration of nitric oxide (NO) to ex vivo fluids. Examples of such fluids include blood in extracorporeal membrane oxygenation (ECMO) circuits or perfusion fluids used for preserving ex vivo organs prior to transplanting in a recipient. The systems and methods described herein provide for administering nitric oxide to the fluid, monitoring nitric oxide or a nitric oxide marker in the fluid, and adjusting the nitric oxide administration.

Various methods and systems for delivery of an ETT for intubation are provided. In one example, an ETT delivery system includes a rail system for guiding insertion of an ETT and at least partially defining the motion of the ETT. The ETT delivery system further may include a video laryngoscope blade coupled to the rail system and a delivery mechanism. In some examples, the ETT delivery system further includes a positioner configured to adjust the motion of the ETT. As a further example, the ETT delivery system may include a swing arm and a guide rail to at least partially define the motion of the swing arm. Further, a drive-down mechanism may effect motion of the swing arm. As another embodiment, a rail system, a disposable blade and a positioner may be provided. Further, a delivery mechanism may be operatively linked with the integrated rail system.

A resuscitation bag system (1) useable for resuscitating a person in cardiac arrest, and having a gas control unit (90) with a first valve (92) fluidly connected to a first (922) and to a second conduit (923), the first (922) and second conduits (923) being arranged in parallel and further fluidly connected to the first conduit element (56), the first conduit (922) having a first flow restriction (924) configured for limiting the gas flow to a first flowrate, and the second conduit (923) comprising second flow restriction (925) configured for limiting the gas flow to a second flowrate, with the second flowrate being less than the first flowrate.

The embodiments use an innovative approach with the goal of permanent eradication of the virus. Instead of using drugs that block different stages of the virus life cycle (which have failed to induce a permanent cure), or approaches attempting to track infected cells, the embodiments use small virucidal molecules that are known to destroy the virus in vitro and that can easily penetrate all human cells, including memory cells or other reservoir cells. The problem with the use of small molecules is their toxicity to humans or animals when administered in doses sufficient to achieve intracellular concentrations high enough to destroy the virus in all forms. The embodiments overcome these toxicities (especially the comatose state) by using a 24-hour treatment with general anesthesia, endotracheal intubation with hemodynamic support, and controlled monitored ventilation; also, a combination of these molecules are used which decreases toxicity but has additive virucidal effects.

The present disclosure relates to a filter apparatus for filtering liquid from a gas, the apparatus having a first housing having a gas inlet and a gas outlet; a first filter media disposed in the first housing; a second filter media disposed in the housing; and a second housing forming a first collection basin disposed in the flow path between the first filter media and the second filter media, so that a path is defined for the gas flowing from the inlet, through the first filter media, past the collection basin, through the second filter media, and to the outlet. The present disclosure also relates to a method of passing a gas through a coalescing filter media and through a hydrophobic filter media.

A method for determining a chance to enable a zeroing of gas analysis is disclosed herein. The method includes emitting radiation, and receiving emitted radiation, the received radiation comprising a first wavelength range absorbed by the at least one desired gas component and one or more disturbing factor, and a second wavelength range absorbed by the disturbing factor, the first wavelength range differing from the second wavelength range. The method also includes providing to a processing unit a first signal data indicative of a concentration of the at least one desired gas component and absorption of the disturbing factor, and a second signal data indicative of absorption of the disturbing factor. The method also includes determining a stability of the first and second signal data as a function of time, and if they are substantially stable enabling the zeroing to improve a measurement accuracy.