A process (10), with a computer program, a device (30) and a ventilation system (40) detect a leak in a patient gas module, which suctions and analyzes a continuous sample gas stream from a ventilated patient (20), in a ventilation system for ventilating a patient (20). The process includes a determination (12) of a first time curve of a carbon dioxide concentration in a breathing gas mixture of the patient (20) and the determination (14) of a second time curve of a concentration of another gas in the breathing gas mixture, which gas is different from carbon dioxide. The process (10) further includes a determination (16) of a statistical similarity indicator between the first time curve and the second time curve and the detection (18) of the leak based on the similarity indicator.

A method of treating a human subject which is effected by inhalation of gaseous nitric oxide over a period of 8 day to about 28 days is disclosed. The method can be utilized for treating a human subject suffering from, or prone to suffer from, a disease or disorder that is manifested in the respiratory tract, or from a disease or disorder that can be treated via the respiratory tract. The disclosed method can be effected while monitoring one or more of on-site and off-site parameters such as vital signs, methemoglobin levels, pulmonary function parameters, blood chemistry and hematological parameters, blood coagulation parameters, inflammatory marker levels, liver and kidney function parameters and vascular endothelial activation parameters, such that no substantial deviation from a baseline in seen in one or more of the monitored parameters.

Various embodiments are described herein for a controller for controlling the operation of a breathing assistance device that provides breathing assistance to a user. The controller comprises a processor that generates a respiratory index value that is determined during a current monitoring time period to detect a respiratory failure, or predict the respiratory failure when at least one PSG signal is measured. The respiratory index value is compared to a threshold to determine if the control signal needs to be updated to reduce or eliminate respiratory failure that the user is currently experiencing or to prevent a predicted respiratory failure from occurring.

An anesthesia ventilator, for the automated ventilation of a patient, includes an expiratory port and an inspiratory port for connecting a ventilation tube facing the patient for a breathing gas, a breathing gas delivery unit, at least one breathing gas sensor for detecting an anesthetic gas concentration, at least one pressure sensor for detecting a pressure of the breathing gas, as well as at least one computer. The computer is configured to actuate the breathing gas delivery unit as a function of the detected pressure of a preset desired pressure value. The computer is further configured to perform an adaptation of the desired pressure value as a function of the detected anesthetic gas concentration.

An anesthesia ventilator, for the automated ventilation of a patient, includes an expiratory port and an inspiratory port for connecting a ventilation tube facing the patient for a breathing gas, a breathing gas delivery unit, at least one breathing gas sensor for detecting an anesthetic gas concentration, at least one pressure sensor for detecting a pressure of the breathing gas, as well as at least one computer. The computer is configured to actuate the breathing gas delivery unit as a function of the detected pressure of a preset desired pressure value. The computer is further configured to perform an adaptation of the desired pressure value as a function of the detected anesthetic gas concentration.

A process for monitoring a measuring system (110) for mechanical ventilation of a patient (20) is carried out while a fluid connection (40) is established between the patient (20) and a medical device (100). A gas sample is suctioned from the fluid connection (40) and is sent through a gas sensor fluid-guiding unit (52) to a gas sensor array (50). A time curve of the CO2 concentration and O2 concentration in the suctioned gas sample are determined. A concentration change curve of the change over time of the CO2 concentration and the O2 concentration are calculated. A search is made for a time period in which the two concentration change curves continuously have the same sign. Upon detecting such a time period it is checked whether a predefined first leak criterion is met. When this is the case, an indication of a leak (L) is detected.

A process for monitoring a measuring system (110) for mechanical ventilation of a patient (20) is carried out while a fluid connection (40) is established between the patient (20) and a medical device (100). A gas sample is suctioned from the fluid connection (40) and is sent through a gas sensor fluid-guiding unit (52) to a gas sensor array (50). A time curve of the CO2 concentration and O2 concentration in the suctioned gas sample are determined. A concentration change curve of the change over time of the CO2 concentration and the O2 concentration are calculated. A search is made for a time period in which the two concentration change curves continuously have the same sign. Upon detecting such a time period it is checked whether a predefined first leak criterion is met. When this is the case, an indication of a leak (L) is detected.

Ventilator system with multiple inspiratory lumens is provided. The inspiratory lumens are configured so that separate inspiratory lumens provide inspiratory gas mixtures to separate portions of a patient's airways, for instance to separate lungs and/or bronchi. The ventilator system can include one or more expiratory lumens to evacuate expiratory gases from airways. The use of separate inspiratory lumen(s), with expiratory lumen(s), allows for functional separation of structural portions of the lungs, and maintenance of continuous or almost continuous flow through at least part of respiratory cycle via inspiratory and expiratory lumens. This can further reduce dead space and clear suspended therein diseases causative agents with improvement in outcomes, reduce risk of cross-contamination or cross-infection between different parts of airways, for example such as cross-infection from one lung lobe to another lobe or. The ventilator system allows for independent titration of PEEP, pCO.sub.2 and pO.sub.2 with no need for permissive hypercapnia.

A nasal ventilation mask having one or more attachment ports located adjacent to and overlying an upper lip of a patient when worn.

A nasal ventilation mask having one or more attachment ports located adjacent to and overlying an upper lip of a patient when worn.