Methods and apparatus for generating multiple phase-shifted clock signals from a base clock signal using programmable delays at the leaf level in a clock distribution network are described. One example method for generating and distributing multiple phase-shifted clock signals in a programmable integrated circuit (IC) generally includes generating a base clock signal, routing the base clock signal through a clock distribution network in the programmable IC to a leaf node, and applying one or more programmable delays to the base clock signal received from the leaf node to generate the multiple phase-shifted clock signals.

A first inverter in a clock generation circuit is coupled to an input clock signal and has multiple driver slices. Each driver slice includes first transistors that have gates coupled to the input clock signal, second transistors that have sources coupled to rails of a power supply. Each of the second transistors has a drain coupled to a source of one of the first transistors. The second transistors are turned on or turned off based on signaling state of a differential enable signal. A tuning resistor is coupled to the drains of the first transistors and further coupled to an output of the first inverter. A second inverter outputs a quadrature version of the input clock signal and has an input coupled to the output of the first inverter. A first tunable capacitor is coupled to the output of the first inverter.