A device for use in the medical and hospital sector for the diagnosis, induced regeneration of tissue by means of therapeutic percutaneous electrolysis and targeted electro-stimulation based on the use of at least one bipolar needle that includes within a very small area of two electrodes located at the exterior and interior conductor of said bipolar needle, limiting the tissue to be treated within the bevel area of the needle without affecting the surrounding healthy tissue in which said bipolar needle is applied the necessary electrical signals for diagnosing the degree of degeneration and to calculate the necessary electrical charge for treating the damaged tissue while controlling said current in a manner that eliminates the contraindications that currently exist.

A deployment and retraction mechanism for deploying and retracting a deployable component of a surgical instrument includes a gear assembly, a slider, and one or more actuators. The slider is translatable between a proximal position, corresponding to a storage condition of the deployable component, and a distal position, corresponding to a use condition of the deployable component. The actuator(s) is coupled to the gear assembly and is movable from an un-actuated position to an actuated position. The gear assembly is configured such that a full actuation and subsequent release of the actuator(s) translates the slider from one of the proximal or distal positions to the other of the proximal or distal positions while a partial actuation and subsequent release of the actuator(s) translates the slider from one of the proximal or distal positions to an intermediate position and back to the one of the proximal or distal positions.

A deployment and retraction mechanism for deploying and retracting a deployable component of a surgical instrument includes a gear assembly, a slider, and one or more actuators. The slider is translatable between a proximal position, corresponding to a storage condition of the deployable component, and a distal position, corresponding to a use condition of the deployable component. The actuator(s) is coupled to the gear assembly and is movable from an un-actuated position to an actuated position. The gear assembly is configured such that a full actuation and subsequent release of the actuator(s) translates the slider from one of the proximal or distal positions to the other of the proximal or distal positions while a partial actuation and subsequent release of the actuator(s) translates the slider from one of the proximal or distal positions to an intermediate position and back to the one of the proximal or distal positions.

The invention provides a non-invasive treatment device (100) for heating a first (15) and a second (25) inner region of skin using r.f. electrical current, comprising: a first r.f. treatment electrode (10) configured and arranged to allow r.f. current to pass through the first inner region (15) to a return electrode (340), a second r.f. treatment electrode (20) configured and arranged to allow r.f. current to pass through the second inner region (25) to the return electrode (340), the device further being arranged such that the smallest distance between the first r.f. treatment electrode (10) and the return electrode (340) is less than the smallest distance between the second r.f. treatment electrode (20) and the return electrode (340); wherein the electrical skin contact area of the return electrode (340) is 5 or more times larger than the electrical skin contact area of the first r.f. treatment electrode (10), and the electrical skin contact area of the second r.f. treatment electrode (20) is 5 or more times larger than the electrical skin contact area of the first r.f. treatment electrode (10). By incorporating the second and first treatment electrodes in the same device, or probe, the positional relationship between the first and second regions being heated is fixed, or at least more predictable. By means of a suitable configuration, the regions may coincide to a smaller or greater degree. In some cases, the configuration may allow the same skin condition to be treated using heating of the first and second inner regions without moving the device over the skin. By providing an electrical skin contact area of the return electrode which is 5 or more times larger than the electrical skin contact area of the first r.f. treatment electrode, the locations heated by the r.f. electrical current will be proximate to the first treatment electrode, reducing the possibility of undesirable hotspots proximate the return electrode (340).

The invention provides a non-invasive treatment device (100) for heating a first (15) and a second (25) inner region of skin using r.f. electrical current, comprising: a first r.f. treatment electrode (10) configured and arranged to allow r.f. current to pass through the first inner region (15) to a return electrode (340), a second r.f. treatment electrode (20) configured and arranged to allow r.f. current to pass through the second inner region (25) to the return electrode (340), the device further being arranged such that the smallest distance between the first r.f. treatment electrode (10) and the return electrode (340) is less than the smallest distance between the second r.f. treatment electrode (20) and the return electrode (340); wherein the electrical skin contact area of the return electrode (340) is 5 or more times larger than the electrical skin contact area of the first r.f. treatment electrode (10), and the electrical skin contact area of the second r.f. treatment electrode (20) is 5 or more times larger than the electrical skin contact area of the first r.f. treatment electrode (10). By incorporating the second and first treatment electrodes in the same device, or probe, the positional relationship between the first and second regions being heated is fixed, or at least more predictable. By means of a suitable configuration, the regions may coincide to a smaller or greater degree. In some cases, the configuration may allow the same skin condition to be treated using heating of the first and second inner regions without moving the device over the skin. By providing an electrical skin contact area of the return electrode which is 5 or more times larger than the electrical skin contact area of the first r.f. treatment electrode, the locations heated by the r.f. electrical current will be proximate to the first treatment electrode, reducing the possibility of undesirable hotspots proximate the return electrode (340).

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. In some embodiments, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy.

A nerve cuff stimulation electrode for cervical VNS is provided and configured to be arranged so as to at least partially surround or enclose one of the vagus nerves. The cuff stimulation electrode has at least two contacts configured to deliver electric stimulation pulses to a vagus nerve. The cuff stimulation electrode further has or may be attached or connected to a tilt sensor, a kinematic sensor, and/or a pulsation sensor configured to generate a signal representative of arterial and venous pressures. The implantable tilt sensor is configured to output a posture signal indicating a patient's posture, thus allowing discrimination between supine and semi-recumbent or erect postures.

A nerve cuff stimulation electrode for cervical VNS is provided and configured to be arranged so as to at least partially surround or enclose one of the vagus nerves. The cuff stimulation electrode has at least two contacts configured to deliver electric stimulation pulses to a vagus nerve. The cuff stimulation electrode further has or may be attached or connected to a tilt sensor, a kinematic sensor, and/or a pulsation sensor configured to generate a signal representative of arterial and venous pressures. The implantable tilt sensor is configured to output a posture signal indicating a patient's posture, thus allowing discrimination between supine and semi-recumbent or erect postures.

Systems and methods for non-invasive management of head pain are disclosed. The system includes a headgear configured to be worn on a patient's head. The headgear can include a base and an extension coupled to the base, and a number of therapy devices removably or adjustably attached to the base or the extension. The therapy devices can deliver various modes of therapeutic energy at respective target sites on the head, including neuromodulation of peripheral pain pathways and/or the cerebral cortex, and therapy modalities to facilitate or enhance the neuromodulation effects. The system can include a portable device that enables the user to control the therapy devices on the headgear. The user can use the portable device to optionally access a web-based repository to acquire information about headgear usage from other users, and use that information to guide the programming of the therapy devices.

Systems and methods for non-invasive management of head pain are disclosed. The system includes a headgear configured to be worn on a patient's head. The headgear can include a base and an extension coupled to the base, and a number of therapy devices removably or adjustably attached to the base or the extension. The therapy devices can deliver various modes of therapeutic energy at respective target sites on the head, including neuromodulation of peripheral pain pathways and/or the cerebral cortex, and therapy modalities to facilitate or enhance the neuromodulation effects. The system can include a portable device that enables the user to control the therapy devices on the headgear. The user can use the portable device to optionally access a web-based repository to acquire information about headgear usage from other users, and use that information to guide the programming of the therapy devices.