Methods and systems for neurostimulation are provided. In one example, a neurostimulation system may include a stimulation module, the stimulation module providing a first stimulation block and a second stimulation block. The neurostimulation system may further include a stimulation interference estimation module for providing an interference model for estimating a spatial interference between the first stimulation block and the second stimulation block. In some examples, the stimulation interference estimation module may reconfigure one or more of the first and the second stimulation blocks to reduce temporal overlap of the stimulation blocks.

An example of a system for delivering neurostimulation energy may include a programming control circuit and a user interface. The programming control circuit may be configured to generate stimulation parameters according to a neurostimulation program including a pattern of interferential stimulation configured to effect asynchronous and/or non-regular activation of nerve fibers by simultaneously delivering a first stimulation current having a first waveform with a first frequency using a first electrode configuration and a second stimulation current having a second waveform with a second frequency using a second electrode configuration. The user interface may be configured to determine the neurostimulation program and to provide the pattern of interferential stimulation with modulation of the first waveform, the second waveform, the first electrode configuration, and/or the second electrode configuration to result in a time-varying beat frequency capable of effecting the asynchronous and/or non-regular activation of the nerve fibers.

A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

An example method includes sending a muscle stimulation current treatment signal to one or more electrodes. The muscle stimulation current treatment signal alternates between on-off states. The method further includes sending, while the muscle stimulation current treatment signal is off, an interferential current treatment signal to the one or more electrodes.

Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

A neuromodulator includes an electromagnetic (EM) wave generator configured to generate EM waves remote from a patient and to direct the EM waves to one or more target regions within the patient. Frequencies of the EM waves fall outside a range of frequencies that activates neurons. Intersection of the EM waves in each target region creates envelope-modulated electric and magnetic fields having one or more frequencies that fall within the range of frequencies that activates neurons. The neuromodulator includes control circuitry configured to control parameters of the EM waves produced by the EM wave generator. The neuromodulator may use feedback based on one or more of patient input and/or sensing of physiological signals in order to close the loop and control the EM waves.

An electrically stimulated CBD infused anesthetic patch system that is placed on a human's skin that is used to relieve pain. The electrically stimulated CBD infused anesthetic patch system comprises of a transdermal patch that has electrodes that receive an electric current from a TENS device. The transdermal patch is impregnated with a solution that has at least one analgesic that is selected from the group consisting of Menthol, CBD, Lidocaine or Capsaicin. The solution shall also include inactive ingredients.

An interferential current therapy kit for treatment of a patient following an orthopedic surgery, includes, within a container for facilitating the distribution and transport of the kit, one or multiple control units including a stimulation power supply and a plurality of electrodes configured to be in electrical communication with the stimulation power supply. The plurality of electrodes are configured to be disposed on an epidermis of the patient and arranged to supply transcutaneous electrical impulses to a therapeutic target area when supplied power by the stimulation power supply employing an interferential current therapy technique. The kit also includes an electrode placement aid adapted to assist the health care provider and team, and the patient with placement of the plurality of electrodes with respect to the site of the previous orthopedic surgery, thereby increasing a likelihood of efficacious and safe placement of the plurality of electrodes.

A medical wound covering for controlling blood flow includes a flexible sheet for covering or surrounding the anatomical site of a wound, such as a surgical drape. The flexible sheet includes a plurality of electrodes electrically connectible to a stimulation power supply. Upon receipt of power from the stimulation power supply, the electrodes supply electrical impulses to the anatomical site of the wound in order to stem or arrest undesired bleeding. In some cases, the stimulation power supply is an interferential therapy power supply, and a pair of electrodes supplies electrical impulses at two different frequencies, the electrical impulses provided at two different frequencies giving rise to at least one beat impulse having an interference frequency. The beat impulse activates the sympathetic nerves to induce vasoconstriction in the local blood vessels. Alternatively, the beat impulse can be programmed to target the parasympathetic nerves if vasodilatation is desired.

Ultrasound (US) apparatus and method for applying low energy US onto an internal tissue/organ, including a non-invasive US appliance used on a treatment region over the internal tissue/organ, and an electrical stimulation apparatus for simultaneously inducing interferential electrical stimulation. A controller controls parameters of the electrical stimulation apparatus and the US appliance, and dynamically changes at least one of the parameters, for maintaining the impedance of the body tissue in the treatment region within an impedance range. The US apparatus includes an impedance monitoring apparatus for continuously measuring, tracking, and monitoring impedance in the treatment region, wherein the controller dynamically changes at least one of the parameter in response to the impedance as monitored, for maintaining the impedance within the predefined range. The internal tissue/organ can be a female fertility organ, which can be, an ovarian follicle, a blood vessel of the uterus (womb), the ovary, the endometrial lining, and the Fallopian tube, ulcer, closed wound, internal injury, inflammation. and nerves.