A balloon catheter comprising: a first shaft having a first lumen and a second lumen; a second shaft located distal to the first shaft; a balloon located distal to the second shaft; and a tubular member that is disposed inside the balloon and has a light transmittance of 90% or more; wherein: the first shaft is made of a resin; a cross-sectional area of the resin forming the first shaft is larger than a cross-sectional area of either the first lumen or the second lumen, which has a larger cross-sectional area, in a cross section perpendicular to a longitudinal direction; a proximal end of the tubular member is joined to a distal end of the first lumen; a proximal end of the balloon is joined to the second shaft; and a distal end of the balloon is joined to the tubular member.

Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device comprises a tissue penetrating member having a distal end and a proximal end, the tissue penetrating member configured to penetrate the tissue of the patient to be inserted into the tissue, wherein the tissue penetrating member is at least partially optically transparent along a surface of the tissue penetrating member positioned between the distal end of the tissue penetrating member and the proximal end of the tissue penetrating member to provide optical transmission of at least a portion of the light through the surface of the tissue penetrating member, thereby allowing at least the portion of the light to be delivered into the tissue of the patient when the tissue penetrating member is inserted into the tissue; and a substrate that supports the tissue penetrating member.

An apparatus and methods for tissue restoration are provided. The apparatus may include a catheter shaft extending from a proximal end to a distal tip, the catheter shaft defining lumens including an inflation lumen and a light fiber lumen, a coated balloon positioned on a translucent distal segment of the catheter shaft proximal to the distal tip in fluid communication with the inflation lumen, the coated distal balloon comprising a translucent material and a coated material on an outer surface of the coated balloon, and a light fiber positioned in the catheter shaft in the light fiber lumen and extending through the translucent distal segment.

An illumination system for a medical technology therapy and/or diagnosis system is provided. The system includes a light source, preferably a laser light source, and a light guide, which at a proximal end can be connected to the at least one light source and/or can be assigned thereto, and which system has at the distal end of the light guide a diffuser element having a longitudinal axis which extends into or in the diffuser element perpendicularly with respect to an input face of the light guide, wherein the diffuser element emits light laterally with respect to the longitudinal axis over its active length in the operating state, wherein the diffuser element has at least one diffuser base body and the diffuser base body contains a matrix that has at least one scattering element and is enclosed at least on its cladding surface by a solid encapsulation.

The present application is directed to devices, assemblies, systems and methods for targeting one or more sites with electromagnetic radiation. The devices, assemblies and systems are operationally configured to transform and convey electromagnetic radiation to one or more targeted sites. The devices, assemblies and systems may also convey one or more fluids or fluid solutions to the one or more targeted sites.

A balloon catheter (1) comprising: a first shaft (10) having a first lumen (11) and a second lumen (12); a second shaft (20) located distal to the first shaft (10); a balloon (30) located distal to the second shaft (20); and an optical fiber (40) disposed inside the balloon (30); wherein: the first shaft (10) is made of a resin; a cross-sectional area of the resin forming the first shaft (10) is larger than a cross-sectional area of either the first lumen (11) or the second lumen (12), which has a larger cross-sectional area, in a cross section perpendicular to a longitudinal direction; the optical fiber (40) is joined to a distal end (11d) of the first lumen (11); a proximal end (30p) of the balloon (30) is joined to the second shaft (20); and a distal end (30d) of the balloon (30) is joined to the optical fiber (40).

Systems, methods, and computer-readable media for enabling ultraviolet radiation treatments are provided.

The present application is directed to devices, assemblies, systems and methods for targeting one or more sites with electromagnetic radiation. The devices, assemblies and systems are operationally configured to transform and convey electromagnetic radiation to one or more targeted sites. The devices, assemblies and systems may also convey one or more fluids or fluid solutions to the one or more targeted sites.

A device includes an angiography module, a phototherapy module, a carrier including an optical filter and accommodating the angiography module and the phototherapy module, and a control unit controlling operation of the angiography module and the phototherapy module. The angiography module includes infrared LEDs emitting infrared light through the optical filter to irradiate a limb of a subject, and an infrared sensor sensing a part of the infrared light reflected off the limb to generate a result, based on which the control unit generates an angiogram. The phototherapy module emits infrared light through the optical filter to irradiate the limb for phototherapy.

A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The optical interface end includes a tapered terminus configured to engage with a cavity of an optical connector adapter, creating an optical interface between the waveguide of the adapter device and a waveguide of a light or radiation source. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.