The invention provides a light generating system (1000) comprising one or more first light generating devices (110), one or more second light generating devices (120), and one or more third light generating devices (130), wherein: – the one or more first light generating devices (110) are configured to generate white first device light (111) having a first color rendering index CRI1 and a first correlated color temperature Tc1; – the one or more second light generating devices (120) are configured to generate white second device light (121) having a second color rendering index CRI2 and a second correlated color temperature Tc2; – the one or more third light generating devices (130) are configured to generate third device light (131) having a third dominant wavelength λd3 selected from the range of 470-500 nm; – CRI1-CRI2≥10; CRI1≥85; Tc2-Tc1≥1000 K; Tc1≤3500 K; and Tc2≥3000 K; and - the light generating system (1000) is configured to generate system light (1001) comprising one or more of the first device light (111), the second device light (121), and the third device light (131).

An optical filter may reduce the frequency and/or severity of photophobic responses or for modulating circadian cycles by controlling light exposure to cells in the human eye in certain wavelengths, such as 480 nm and 590 nm, and a visual spectral response of the human eye. The optical filter may disrupt the isomerization of melanopsin in the human eye reducing the availability of the active isoform, whereas the attenuation of light weighted across the action potential spectrum of the active isoform attenuates the phototransduction cascade leading to photophobic responses. Embodiments of an optical filter are described. In one embodiment an optical filter may be configured to transmit less than a first amount of light in certain wavelengths, and to transmit more than a second amount of light weighted across the visual spectral response. Methods of use and methods of manufacturing optical filters are also described.

The present disclosure provides a circadian rhythm correcting apparatus including a bio-illuminance measuring part configured to measure bio-illuminance of external light, a light source configured to irradiate light of a circadian wavelength band toward a retinal ganglion cell, a light source driver configured to drive the light source by supplying power to the light source, and a controller configured to control the light source driver on the basis of the bio-illuminance measured by the bio-illuminance measuring part, to correct the circadian rhythm.

Devices utilizing holographic 4D plenoptic capture and display technologies to generate a light field function to provide glasses-less vision correction for observers with imperfect vision, and to project an image according to the generated light field function, and methods for calibrating a four-dimensional light field for a user with an uncorrected visual acuity.

A method of treating cognitive impairment associated with chemotherapy treatment in a subject in need thereof includes on-invasively delivering a combined stimulus to the subject to invoke gamma entrainment in a brain of the subject. The combined stimulus includes an auditory stimulus having a frequency of from about 20 Hz to about 60 Hz, and a visual stimulus having a frequency of from about 20 Hz to about 60 Hz.

A sleep mask includes a flexible eye cover configured to be worn by a late-term pregnant female and configured to cover and shield the eyes of the wearer from ambient light. At least one light source is carried by the flexible eye cover and positioned to emit light having a wavelength of 450 to 570 nm onto the eyelids of the wearer when asleep and penetrate the eyelids when closed. A controller is connected to the at least one light source and configured to activate the light source to decrease endogenous melatonin levels and suppress uterine contractions in the late-term pregnant female.

The present invention relates to a smartphone interface device for phototherapy which performs communication with a smartphone by using a micro controller unit (MCU) installed in the smartphone interface device for phototherapy and a universal serial bus on-the-go (USB OTG) module, and is capable of controlling a light beam irradiator more stably to enable the light beam irradiator to be driven. The present invention pertains to a smartphone interface device for phototherapy comprising: a micro controller unit (MCU) for receiving, from a smartphone, light beam irradiation intensity, light beam irradiation time, light beam irradiation pattern, and light beam irradiation start and end-relevant light beam irradiating electrode control commands, and generating a light source drive control signal according to the received light beam irradiating electrode control commands; a universal serial bus on-the-go (USB OTG) module; a voltage regulator; and a light beam irradiation drive unit.

A system to provide circadian-friendly lighting for nighttime hospital care comprising a lighting module and a transmitter tag that interface wirelessly wherein the lighting module comprises red-shifted light spectra, which is proven to be less disruptive to melatonin production than current blue-shifted hospital lighting; wherein the light output of the devices is modulated by the proximity of a tag to the device, with light intensity increasing with closer proximity between these two components and decreasing with increased distance, thereby providing hands-free lighting to caregivers in the specific locations where they need light to perform care tasks.

A method and computer program product for suppressing the symptoms of multiple sclerosis (MS) by irradiating a subject exhibiting the symptoms with a pre-determined dose of UV-containing light from a light source and detecting a suppression of the clinical symptoms of MS. In particular, the detected suppression of the clinical symptoms is disassociated from the vitamin D production within the subject.

An apparatus comprises a data processing unit and a stimulator. The data processing unit receives first electroencephalographic data based on a measurement of a brain of a person exposed to one or more estimated or measured non-zero amounts of anesthetic drug substance. The data processing unit performs a first comparison between the first electroencephalographic data and corresponding data of a reference brain function, and outputs information about the first comparison. The stimulator provides the brain of the person exposed to the anesthetic drug substance with brain stimulation on the basis of a direct or indirect reception of the information about the first comparison.