A device inserted into a living body to generate an anticancer material is disclosed. The disclosed device comprises: an electric energy converter which receives an external signal to convert the external signal into electric energy; at least one electrode pair for causing electrolysis in a body fluid inside the living body by using the electric energy converted by the electric energy converter; and a light emitter for emitting light at a by-product produced by means of electrolysis by using the electric energy converted by the electric energy converter.

An illumination system for a medical technology therapy and/or diagnosis system is provided. The system includes a light source, preferably a laser light source, and a light guide, which at a proximal end can be connected to the at least one light source and/or can be assigned thereto, and which system has at the distal end of the light guide a diffuser element having a longitudinal axis which extends into or in the diffuser element perpendicularly with respect to an input face of the light guide, wherein the diffuser element emits light laterally with respect to the longitudinal axis over its active length in the operating state, wherein the diffuser element has at least one diffuser base body and the diffuser base body contains a matrix that has at least one scattering element and is enclosed at least on its cladding surface by a solid encapsulation.

A quantum dot (QD)-rhodopsin bioconjugate system uses Förster resonance energy transfer (FRET)-mediated induction of cellular membrane depolarization via optical activation of ion channel proteins channelrhodopsin (ChR).

Devices, materials, compounds, systems, and processes for Cherenkov-Activated Nuclear-Targeted Photodynamic Therapy that involves generating Cherenkov light within the tissue of a target volume and using this light to activate photosensitizing material that is located in the nucleus of cells of the target volume.

A phototherapy face mask is provided for emitting therapeutic radiation towards the facial region of a user and aims to restore the youthful appearance of the user who is wearing the mask. The phototherapy mask comprises an outer surface and an inner surface, wherein the inner surface is aligned with the facial skin of the user. A flexible PCB layer is provided between the inner surface and the outer surface, on which a plurality of coherent light sources such as LEDs are mounted. The light sources are configured to emit radiation preferably in the visible and infrared range of the electromagnetic spectrum. The mask further includes a medicament chamber which is operably coupled to a piezoelectric pump that dispenses the medicament at regular intervals. The medicament is uniformly distributed all over the facial region of the user through a plurality of pores of the mask.

Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, metal ion-noncovalently bound apotransferrin (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer. Thermal therapy using the sensitizing composition effectively treats cancer without pain or side effects and is thus expected to be widely useful in anticancer treatment as monotherapy, and/or in combination with chemotherapy, radiation therapy, or a combination thereof, ultimately increases the potential to cure cancer.

Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

The present disclosure provides a method for treating clinical or pre-clinical skin damage in a skin field of a subject, wherein the skin field has been allocated a skin cancerization field index (SCFI) score of at least 1 as determined by a process comprising the steps of: (i) assessing the number of keratoses in the skin field; (ii) assessing the thickness of the thickest keratosis in the skin field; and (iii) assessing the proportion of the field affected by clinical or subclinical skin damage. Based on the assessments made in (i), (ii) and (iii) the subject is optionally treated by at least one of (a) freezing one or more lesions, (b) shaving, curetting or surgically removing one or more lesions, (c) applying a topical treatment for actinic keratosis, basal cell carcinoma or squamous cell carcinoma, and (d) radiation therapy.

Described herein are systems and methods for a type of paradigm-shift nanoparticles functionalized endothelial optical exosomes for vascular malformation treatment, including Port Wine Stain, using exosomes as a drug delivery vehicle in combination with Near-Infrared-mediated laser therapy.

A treatment apparatus and a treatment method capable of minimally invasively specifying a lesion extent and checking progress of treatment while performing the treatment for destroying tumor cells. The treatment apparatus that detects and destroys a tumor cell by irradiating an antibody-photosensitive substance adsorbed on a tumor cell membrane with excitation light includes: an elongated tubular shaft having optical transparency; a light irradiation unit configured to emit the excitation light of the antibody-photosensitive substance from an inside of the shaft in a side direction perpendicular to an axial direction of the shaft; and a side direction fluorescence detection unit configured to detect, from the side direction perpendicular to the axial direction of the shaft, fluorescence emitted by the excited antibody-photosensitive substance, and movable in the axial direction with respect to the shaft.