One embodiment is directed to a system for altering the function of a sensory unit that innervates a targeted tissue region in an animal, the sensory unit being configured to express a light-responsive protein, comprising a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure; and a light source configured to provide light to the light delivery element; wherein the targeted tissue structure is illuminated transcutaneously with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light-responsive protein to the radiation.

Low-level light therapy system with an electrically passive, article of apparel that absorbs an incident spectrum including one or more of a UV wavelength, a visible wavelength, and a near infrared wavelength and emits light having an emission spectrum including visible light radiation and near infrared radiation. Light is emitted from the yarns and a textile material consisting of a network of yarns (as well as the article of apparel made from such a textile material) having an emission spectrum including visible light radiation and near infrared radiation in a direction toward a body of a person. An article of apparel that emits light in the visible/near infrared spectrum, a method of manufacture, and a low-level light therapy method are also disclosed.

The present invention relates to a simple-to-use, phototherapy dose delivery system. More particularly, a two-component irradiator having a first component being antimicrobial light source and the second being an expendable, hollow, beam sleeve. The beam sleeve being constructed to slide partially over a bezel end of the light source thereby capturing and transforming the source light into a contained, homogeneous treatment spot of calibrated treatment intensity. The calibrated intensity enables protocols and dose times to become universally the same for all irradiators once paired with a fitting beam sleeve, regardless of spot size or spectra. In practice the beam sleeve defines the treatment spot diameter, gauges the working distance, sets the dose rate, all while blocking stray light from disrupting vision. In this modular manner the light source and beam sleeve work similarly as a syringe and needle; when used together the predetermined dose and rate are administered to a precise location in accurate amounts.

Low-level light therapy system with an electrically passive, article of apparel that absorbs an incident spectrum including one or more of a UV wavelength, a visible wavelength, and a near infrared wavelength and emits light having an emission spectrum including visible light radiation and near infrared radiation. Light is emitted from the yarns and a textile material consisting of a network of yarns (as well as the article of apparel made from such a textile material) having an emission spectrum including visible light radiation and near infrared radiation in a direction toward a body of a person. An article of apparel that emits light in the visible/near infrared spectrum, a method of manufacture, and a low-level light therapy method are also disclosed.

A system and method for emitting a wavelength of energy internal to a medium or internal to a human or animal subject, and methods for using the system in the treatment of a condition, disorder, or disease. The system includes 1) a source configured to produce an initiation signal penetrating at least a part of the medium or the human or animal subject and 2) an insertion device having an electronics assembly unit. The assembly unit includes 1) an emitter configured to emit the wavelength of energy of a predetermined type to treat a disease or disorder in the human or animal subject or to produce a change in the medium and 2) a receiver that receives the signal.

A method of regulating at least one cellular process in one or more cells by exposing the one or more cells to ultrasound, characterised in that the method comprises either (a) introducing into the one or more cells a construct comprising a regulatory transgene capable of regulating the at least one cellular process operably linked to a light-inducible control sequence and (b) inducing the expression of the regulatory transgene using sonoluminescence (SL) or sonochemiluminescence (SCL); or (i) contacting the one or more cells with one or more light-sensitive proteins capable of regulating the at least one cellular process and (ii) regulating the function of the one or more proteins using sonoluminescence or sonochemiluminescence.

The present disclosure provides methods for generating tunable white light with controllable circadian energy performance. The methods use a plurality of LED strings to generate light with color points that fall within blue, yellow/green, red, and cyan color ranges, with each LED string being driven with a separately controllable drive current in order to tune the generated light output. Different light emitting modes can be selected that utilize different combinations of the plurality of LED strings in order to tune the generated white light.

An ultraviolet light-emitting phosphor having excellent degradation resistance and emission intensity is provided. The ultraviolet light-emitting phosphor is a phosphor comprising yttrium element, scandium element, aluminum element and oxygen element, which is excited by irradiation of vacuum ultraviolet rays or electron beams to emit ultraviolet rays.

The present disclosure provides methods for generating tunable white light with controllable circadian energy performance. The methods use a plurality of LED strings to generate light with color points that fall within blue, yellow/green, red, and cyan color ranges, with each LED string being driven with a separately controllable drive current in order to tune the generated light output. Different light emitting modes can be selected that utilize different combinations of the plurality of LED strings in order to tune the generated white light.

The present invention relates, inter alia, to dermal systems comprising at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal systems can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient.