Methods for selectively stimulating a plurality of light-responsive neurons in a sample are provided. Methods according to certain embodiments include irradiating a sample comprising a plurality of light-responsive neurons with a plurality of holographic images that are each configured to stimulate one or more light-responsive neurons in the sample, wherein the holographic images are created by light projection system that includes a plurality of light sources; a plurality of optical adjustment components; a plurality of spatial light modulators; a controller; a processor; and a computer-readable medium comprising instructions that, when executed by the processor, cause the controller to operate the light sources, optical adjustment components and spatial light modulators to generate and display a plurality of holographic images; direct each of the holographic images to a projection location; and project the holographic images onto the sample at a rate greater than 1 kHz. Light projection systems for irradiating a sample having light-responsive neurons with holographic images are also described.

This current disclosure is directed to charge-transfer heptamethine dyes for NIR singlet oxygen generation, each such dye comprising a near-infrared (NIR) absorbing dye having heptamethine linkages orthogonally coupled to an optionally substituted cationic heteroaryl ring moiety as a charge-transfer partner and uses thereof.

The present disclosure relates to an EEG measuring device which is in close contact with a head of a subject while having an adjustable size to fit the head of the subject.

Provided is a mouthpiece which is mounted in an oral cavity for use in changing the shape of the skull including the maxillary bone and is composed of a plurality of segment pieces, at least some of the segment pieces being configured to approach or be spaced apart from each other by means of a screw, wherein the surfaces of the segment pieces facing or contacting the skin in the oral cavity are configured such that the segment pieces overlap with each other, such that a gap does not occur in spite of the approaching or spacing-apart movement of the segment pieces relative to each other.

A self-administrable system for improving athletic performance of a subject, the said system comprising: configured irradiation units comprising a first, a second, a third and a fourth configured irradiation unit, wherein: (A) said first configured irradiation unit is positioned to direct light energy to a first region of the brain comprising the OZ position of the primary visual cortex; (B) said second configured irradiation unit is positioned to direct light energy to a second region of the brain comprising the CZ position of the primary sensorimotor cortex; (C) said third configured irradiation unit is positioned to direct light energy to a third region of the brain comprising the C3 position of the primary sensorimotor cortex; and (D) said fourth configured irradiation unit is positioned to direct light energy to a fourth region of the brain comprising the C4 position of the primary sensorimotor cortex.

A radiation treatment device comprises a radiation source layer comprising a radiation source and a controller. The radiation source is configured to emit radiation with a wavelength in the range 822 nm to 1322 nm. In a preferred embodiment, the device configured to emit radiation with a wavelength of 1067 to 1077 nm.

Provided are a treatment apparatus and a treatment method capable of effectively treating cancer tumor cell (for example cancer in a range including at least a part of a cervix). A treatment apparatus is configured to irradiate an antibody-photosensitive substance bound to a tumor cell with excitation light, and includes: a main shaft including a distal portion and a proximal portion; a distal structure portion disposed on a distal side of the main shaft and formed to be larger than the main shaft in a radial direction of the main shaft; a distal shaft protruding from the distal structure portion toward the distal side; and at least one irradiation unit configured to emit the excitation light of the antibody-photosensitive substance from the distal shaft and the distal structure portion.

A treatment apparatus and a treatment method capable of effectively treating cancer in a range including at least a part of a cervix. A treatment apparatus is configured to irradiate an antibody-photosensitive substance accumulated in a tumor cell with excitation light, and includes: a tubular device including an elongated tubular member; and an irradiation device configured to be inserted into the tubular member. The irradiation device includes a main shaft including a distal portion and a proximal portion, a disk portion disposed on a distal side of the main shaft, a distal shaft protruding from the disk portion toward the distal side, and an irradiation unit disposed on the distal shaft and configured to emit the excitation light.

A wearable device that selectively reflects biophotons emitted naturally from the user's body back into the body, achieving beneficial health effects similar to low-level laser therapy without requiring an external laser device. Illustrative wavelengths that may be reflected may include 550 nm, 630 nm, 632 nm, 660 nm, 694 nm, 810 nm, and 980 nm. Radiation of wavelength 810 nm in particular has been shown to affect mitochondrial energy production. The device may be worn for example as a bracelet or pendant. Internal components may include one or more filters to select the desired wavelengths, and a parabolic mirror to reflect these selected wavelengths back into the body. Some embodiments may also include a polarizer so that reflected waves are polarized.

Systems and techniques for configuring a light therapy oral guard include receiving sensed data from a first sensor associated with the light therapy oral guard, providing the sensed data from the first sensor to a machine learning model, receiving a machine learning output from the machine learning model based on the sensed data from the first sensor, the machine learning output comprising a light therapy oral guard configuration, and configuring the light therapy oral guard based on the light therapy oral guard configuration.