The present invention describes a method of killing or inactivating microorganisms, the method comprising the steps of contacting the microorganisms with a composition comprising an extract of Polygonum cuspidatum and an excipient; and irradiating the microorganisms with a source of light; wherein the radiant exposure of the light is between 1 and 300 J cm.sup.−2, and the surface power density of the light is between 0.001 and 0.25 W cm.sup.−2.

A wearable fabric for photo-stimulating a biological system includes at least one piece of textile, a plurality of bioceramic particles, and at least one nutrient-based precursor. The at least one piece of textile includes a plurality of interwoven polymeric fibers, an outer textile surface, and an inner textile surface. The outer textile surface and the inner textile surface are positioned opposite to each other about the at least one piece of textile. The quantity of bioceramic particles is uniformly integrated amongst the plurality of interwoven polymeric fibers. The at least one nutrient-based precursor is integrated amongst the plurality of interwoven polymeric fibers as the at least one nutrient-based precursor is configured to frictionally dislodge from the plurality of interwoven polymeric fibers as the inner textile surface is in physical contact with a wearer's skin to stimulate the production of Vitamin D and to stimulate bone growth.

A collagen cross-linking system for treating a tissue of a patient, the system including: a catheter having a flexible shaft and a conforming member, the flexible shaft having distal and proximal ends, a shaft body extending between the distal end and the proximal end, the shaft body defining a lumen, the conforming member being fixed to the catheter shaft near the distal end, the conforming member comprising a membrane defining a cavity in fluid communication with the lumen; a fluid source coupled to the proximal end of the catheter, the flexible shaft of the catheter being configured so that a flow of photosensitizing fluid provided by the fluid source flows through the membrane of the conforming member; and a light source coupled to the proximal end of the catheter, the catheter being configured so that photo-activating light generated by the light source passes through the membrane of the conforming member.

A method comprises determining (203) whether a person has been and/or will be irradiated with an amount of UV radiation exceeding a threshold and controlling (205), in dependence on the determination, one or more light sources to render light comprising a light component having wavelengths in the range 550 to 900 nm. A spectral power distribution of the light is chosen such that the light has a cytochrome C oxidase efficacy complying with the following conditions: for DNA synthesis: the cytochrome C oxidase efficacy is at least 6.2*vʹ-2.48 mW/lm if the light’s vʹ is lower than 0.539 or at least 0.85 mW/lm if the light’s vʹ is equal to or higher than 0.539; for RNA synthesis: the cytochrome C oxidase efficacy is at least 7.5*vʹ-2.975 mW/lm if the light’s vʹ is lower than 0.539 or at least 1.05 mW/lm if the light’s vʹ is equal to or higher than 0.539.

A treatment system includes a treatment device adapted to contact a vulvar or vaginal tissue of a body and includes a treatment mechanism configured to apply a treatment to the tissue and at least one sensor configured to provide objective sensor data related to the tissue. An external device is configured to receive subjective information provided by a user or a third party and to receive the objective sensor data from the treatment device. The external device includes a processor configured to use the subjective information and the objective sensor data in a decision matrix to issue commands to at least the treatment mechanism that correspond to treatment instructions based on the subjective information and the objective data. The treatment instructions include instructions related to controlling the treatment mechanism and its application of treatment to the tissue and a treatment duration.

A skin measurement apparatus for emitting a plurality of lights for photographing an image of the skin. A skin measurement apparatus includes an ultraviolet ray emitting device; a white light emitting device; a focus lens enabling incident light, which is an ultraviolet ray emitted by means of the ultraviolet ray emitting device and a white light emitted by means of the white light emitting device reflected off the skin and transmitted, to pass therethrough; and an emission control device for controlling the ultraviolet ray emitting device and the white light emitting device such that the ultraviolet ray and the white light can be emitted together. The emission control device adjusts the strength of the white light on the basis of white light control information from the outside.

The present invention relates to a flexible skin patch equipped with an ultra-thin LED assembly that emits light in a specific wavelength range and an invention for manufacturing the same, and is related to an invention capable of providing a flexible skin patch that has the excellent effect of promoting vitamin D production in a localized area of the skin, and has the effect of alleviating or treating local skin psoriasis, fungi, fungal tumors and eczema, and has excellent antiviral effect, and is easy to attach and detach.

The present invention relates to a therapy for vitiligo. In particular the present invention provides a pharmaceutical composition comprising an alpha melanocyte stimulating hormone (alpha-MSH) analogue either alone, in combination with narrow band UVB and/or in combination with one or more corticosteroids, immunosuppressants, anti-inflammatory agents and/or photochemotherapeutic agents for the treatment or prevention of vitiligo.

An irradiation device capable of emitting electromagnetic radiation at variable beam angles, comprises, a housing assembly including a longitudinal shell, the longitudinal shell having a first end and a second end, a first end cap assembly provided at the first end of the longitudinal shell, and a second end cap assembly provided at the second end of the longitudinal shell. Further, the irradiation device comprises a rotate and lock mechanism adapted to allow rotational adjustment of the longitudinal shell, a plurality of lenses provided along with the longitudinal shell, wherein each one of the plurality of lenses has a distinct set of optical characteristics when compared with other lenses of the plurality of lenses and a radiation source configured to emit electromagnetic radiation, provided within the longitudinal shell.

A pharmaceutical composition for modifying a target structure, which includes at least one agent selected from the group consisting of energy modulation agents, plasmonics-active agents and combinations thereof; the energy modulation agents, when present, including one or more light emitters capable of emitting at least two different wavelengths of light, each wavelength of light associated with a different biological response, and the at least two different wavelengths capable of activating different biological responses; and a pharmaceutically acceptable carrier.