Methods and devices are disclosed for infrared phototherapy. The device can include a flexible substrate, a plurality of infrared light sources associated with the substrate and a drive circuitry configured to couple to a power supply and connected to the light sources to activate the light sources to emit infrared radiation. The device can be positioned on a subject's body to transmit infrared radiation to a target region of skin or muscle tissue of a subject to raise the temperature of the target region above normal body temperature. The plurality of light sources can be disposed in a spaced-apart relationship on the substrate such that collectively they emit infrared radiation in an overlapping pattern that provides for substantially uniform exposure of a target region. The substrate can be actively cooled to control the surface temperature of the target region. The device can further include a light-transmissive sealing element to isolate the LEDs from contact with the subject's body.

The present invention relates to a laser therapy device and a light transmitting member comprising: a main body provided with a laser light source; a light irradiation unit for irradiating a laser generated in the laser light source to a treatment site; and a light transmitting unit provided between the main body and the light irradiation unit so as to form a path through which the laser is transmitted, wherein the light transmitting unit comprises a plurality of arm members connected by joint parts, and at least one of the plurality of arm members has therein a vacuum forming unit at a position where the laser is focused. According to the present invention, by configuring a compact structure, it is possible to improve the quality of a laser outputted to a treatment site.

Embodiments of the present disclosure relate to a head-worn apparatus, comprising: a frame adapted to be mounted to a head of a user; a light emitting system positioned within the frame to provide light to an eye of the user; a sound system adapted to provide audio to the user; a haptic system positioned within the frame to provide haptic feedback to the user; and a processor adapted to control the lighting system, audio system and haptic system in a coordinated pattern of light, sound and haptics that causes a mental-health therapeutic stimulus provided to the user, whereby the user experiences an improvement in mental performance based on the coordinated pattern.

A wireless optogenetic device in proximity to a neural cell of a subject includes a body configured to hold light transducing materials arranged to up-convert electromagnetic radiation in infrared or near-infrared spectrum into light in the visible spectrum to affect activity of the neural cell. The body allows electromagnetic radiation in infrared or near-infrared to reach the light transducing materials. A radiation system includes a radiation probe for irradiating a wireless optogenetic device with electromagnetic radiation in infrared or near-infrared spectrum from a radiation source. The system further includes a movement mechanism for moving the radiation probe, a detector for detecting a location of the wireless optogenetic device, and a controller for controlling the movement mechanism based on the detected location of the wireless optogenetic device such that the radiation probe is arranged to irradiate the wireless optogenetic device at the detected location with the electromagnetic radiation.

The disclosure relates to a cancer treatment system including: a radiation source configured to produce 1.27-micrometer wavelength radiation, wherein the 1.27-micrometer wavelength radiation is generated from singlet oxygen. The radiation source may be an oxygen laser or an amplified spontaneous emission generator. The 1.27-micrometer wavelength radiation may be a laser or an amplified spontaneous emission.

A light treatment system includes: a probe configured to be inserted into a bladder, the probe including an optical fiber configured to propagate light, and a light emitter that is provided at a distal end of the optical fiber, the light emitter being configured to emit the light; and a balloon catheter into which the probe is inserted, the balloon catheter being configured to be inserted into the bladder, the balloon catheter including a distal end portion that is to be dilated in the bladder, a wall configured to divide inside of the distal end portion into two regions, and a reflector configured to reflect the light emitted by the light emitter, the reflector being provided on a surface of the wall, the surface facing a region of the two regions, the region being where the light emitter is positioned.

Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing an NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.

The present disclosure is directed to a phototherapeutic apparatus for focused UVB radiation and vitamin D synthesis and associated systems methods. In one embodiment a phototherapeutic apparatus can include a housing at least partially defining an irradiation zone, and an ultraviolet (UV) radiation source carried by the housing. The irradiation zone can be configured to accommodate at least a portion of a human patient. The phototherapeutic apparatus can further include a filter between the UV radiation source and the irradiation zone. The filter can be configured to at least substantially remove UV radiation outside of a predetermined spectrum centered at about 297 nm and having a bandwidth of at most 10 nm.

An object is to uniformly irradiate a non-flat affected area with light. Provided is an irradiation apparatus (1) configured to irradiate a projecting part of a body of an irradiation target organism with light, the irradiation apparatus including: a cover (2); a light source unit (3); and a sheet (4) that is provided so that the light source unit (3) does not make contact with an affected area of the projecting part or an area surrounding the affected area, the sheet (4) and/or the cover (2) being configured to make contact with the area surrounding the affected area.

A device for treating the brain includes a light source configured to emit near infrared light. The device also includes a collimator configured to receive the near infrared light emitted by the light emitter. The collimator is further configured to collimate the near infrared light. The device also includes an optic configured to focus collimated light. A reflector of the device is configured to change a direction of the collimated light. The reflector is at a distal end of the device, and the distal end is configured to fit between an upper portion of an eyelid of a patient and an orbital socket of the patient.