An optical filter may reduce the frequency and/or severity of photophobic responses or for modulating circadian cycles by controlling light exposure to cells in the human eye in certain wavelengths, such as 480 nm and 590 nm, and a visual spectral response of the human eye. The optical filter may disrupt the isomerization of melanopsin in the human eye reducing the availability of the active isoform, whereas the attenuation of light weighted across the action potential spectrum of the active isoform attenuates the phototransduction cascade leading to photophobic responses. Embodiments of an optical filter are described. In one embodiment an optical filter may be configured to transmit less than a first amount of light in certain wavelengths, and to transmit more than a second amount of light weighted across the visual spectral response. Methods of use and methods of manufacturing optical filters are also described.

An implantable device for implantation in a human body or animal body. The device includes an energy source, an energy storage device, and an electronics unit. Further, an actuator is coupled with the energy storage device and it is configured to emit electromagnetic waves by discharging the energy storage device.

The present disclosure relates to light emitting devices, systems and methods for use in animal nests, such as mink nests or piglet nests, for enhancing the formation of ND3 in animals and minimizing the microbial pressure in the animal nest, while providing the animals with an improved resting condition. A light emitting device comprises at least one UVB light source, wherein the light emitting device is configured such that UV light below 285 nm is not emitted from the device, visible light between 380 and 750 nm is not emitted from the device, and light in a wavelength interval of 290 nm-315 nm is emitted from the device.

A device comprising a housing having a handle end and a treatment end. The treatment end is configured to provide an antimicrobial treatment and a heat treatment. The treatment end comprises an applicator having an applicator surface for providing at least the heat treatment. The device includes a heat generation unit configured to heat the applicator surface in use, a source of antimicrobial agent, and a control unit operatively connected to at least the heat generation unit for controlling the heat generation unit. The device can be a hand-held device and used to apply topical treatment to a treatment area of a subject.

Certain exemplary embodiments of the present disclosure can provide an apparatus and method for generating at least one radiation can be provided. The exemplary apparatus and/or method can selectively kill and/or affect at least one virus. For example, a radiation source first arrangement can be provided which is configured to generate at least one radiation having one or more wavelengths provided in a range of about 200 nanometers (nm) to about 230 nm, and at least one second arrangement can be provided which is configured to prevent the at least one radiation from having any wavelength that is outside of the range can be provided or which can be substantially harmful to cells of the body.

An optical filter may reduce the frequency and/or severity of photophobic responses or for modulating circadian cycles by controlling light exposure to cells in the human eye in certain wavelengths, such as 480 nm and 590 nm, and a visual spectral response of the human eye. The optical filter may disrupt the isomerization of melanopsin in the human eye reducing the availability of the active isoform, whereas the attenuation of light weighted across the action potential spectrum of the active isoform attenuates the phototransduction cascade leading to photophobic responses. Embodiments of an optical filter are described. In one embodiment an optical filter may be configured to transmit less than a first amount of light in certain wavelengths, and to transmit more than a second amount of light weighted across the visual spectral response. Methods of use and methods of manufacturing optical filters are also described.

The present application is directed to a method for the regulation of the development of ocular refractive errors, comprising: controlling at least one light source using a processor, the at least one light source emitting an electromagnetic radiation variable with respect to one or more of a direction, an illuminance, a retinal area, an amplitude, a wavelength, and a spectral output; and regulating the at least one light source and producing a spectral power distribution at a plane of an eye.

An assembly for photomedicine therapy comprising: (a) at least partially transparent body having an internal cavity; the internal cavity provided with input and output pipes configured for circulating a cooling agent via said internal cavity; and (b) at least one electrically energizable light source disposed within said internal cavity such that radiation from said at least one light source propagates to the ambient surroundings.

A liquid-containing heat filter for use with a high-intensity light, said liquid-containing heat filter comprising a substantially hollow reservoir for receiving heat-filtering liquid therein, the reservoir comprising a first optically transparent member, a second optically transparent member, and a peripheral frame for receiving and retaining said first optically transparent member and said second optically transparent member, heat-filtering liquid disposed in said substantially hollow reservoir, and a first resiliently deformable member interposed in trapped relation between the first optically transparent member and a first portion of said peripheral frame, wherein, in use, when the heat-filtering liquid in the reservoir raises in temperature due to the heating effect of the high-intensity light, the first resiliently deformable member is compressed to thereby allow the outward movement of the first optically transparent member due to expansion of the heat-filtering liquid.

Devices, systems, and methods for a treating dementia or Alzheimer's disease in a subject in need thereof. In one example, combined auditory and visual stimuli having a frequency of about 20 Hz to about 60 Hz, and more specifically about 40 Hz, are non-invasively delivered to the subject to induce synchronized gamma oscillations in at least one brain region of the subject. In particular, pursuant to various treatment and exposure protocols, combined auditory and visual stimulation (as opposed to auditory or visual stimulation alone) promotes a microglia response in the medial prefrontal cortex (mPFC). More generally, combined auditory and visual stimulation induces an extended microglia clustering response in the auditory cortex, the visual cortex, and the mPFC.