A system with integrated tracking includes a procedure-specific hardware component (112 or 116) disposed at or near a region of interest. A field generator (114) is configured to generate a field with a field of view covering the region of interest. A mounting device (115) is connected to the field generator and is coupled to the procedure-specific hardware. The field generator is fixedly positioned by the mounting device to permit workflow access to the region of interest without interfering with the field generator and to provide a known position of the field generator relative to the region of interest. A tracking device (110) is configured to be inserted in or near the region of interest to be tracked within the field of view of the field generator to generate tracking data.

The invention relates to the radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. In particular the invention relates to an endorectal probe device for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. Furthermore the invention relates to an afterloading apparatus for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject using an endorectal probe device according to the invention. Moreover the invention relates to a method for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject, wherein the method implements the endorectal probe device according to the invention.

The invention relates to a holder device for holding a medical instrument, the device comprising:

a base that is to be carried by an apparatus comprising a medical imaging probe associated with the medical instrument; and

a carrier structure for carrying the medical instrument and movably mounted on the base so as to be capable of moving on the base between a first position and a second position.

The invention also relates to an installation including both such a device and a needle-guide.

Systems and methods are provided for treating cervical and/or uterine cancers in brachytherapy with an intracavitary brachytherapy applicator. The system comprises a tandem adapted for insertion into a cervix of a patient. An ovoid assembly comprises first and second inflatable ovoids and an ovoid support mechanism. The first and second inflatable ovoids are adapted for insertion within fornices of a patient. First and second retractors are adapted to be coupled to the ovoid assembly. The first retractor is adapted to be positioned to retract the bladder of a patient during treatment. The second retractor is adapted to be positioned to retract the rectum of a patient during treatment. The tandem and the first and second inflatable ovoids are adapted to be coupled to a radioactive source to deliver an implant radiation dose suitable for cancer treatment at a cancerous cervical treatment site in a patient.

The invention relates to a device for supporting the testing of a brachytherapy applicator prior to the use of the brachytherapy applicator in brachytherapy radiation treatments. The invention also relates to a method for testing of a brachytherapy applicator prior to the use of the brachytherapy applicator in brachytherapy radiation treatments.

Compositions and methods for treating, detecting, and diagnosing cancer are disclosed.

Systems and methods are provided for treating cervical and/or uterine cancers in brachytherapy with an intracavitary brachytherapy applicator. The system comprises a tandem adapted for insertion into a cervix of a patient. An ovoid assembly comprises first and second inflatable ovoids and an ovoid support mechanism. The first and second inflatable ovoids are adapted for insertion within fornices of a patient. First and second retractors are adapted to be coupled to the ovoid assembly. The first retractor is adapted to be positioned to retract the bladder of a patient during treatment. The second retractor is adapted to be positioned to retract the rectum of a patient during treatment. The tandem and the first and second inflatable ovoids are adapted to be coupled to a radioactive source to deliver a radiation dose suitable for cancer treatment at a cancerous cervical treatment site in a patient.

Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.

The radiotherapy applicator system includes an applicator pad adapted to cover a target area of a patient for radiation treatment. One or more spaced channels extend through a length of the applicator pad. Each channel receives a catheter sleeve, and an elongate seed line is selectively inserted into a corresponding catheter sleeve. Each seed line contains one or more radioactive seeds and spacers arranged in a predetermined pattern along the length of the seed line. The seed lines within the applicator pad form an array of a predetermined, geometric treatment pattern of seeds covering the target area, the treatment pattern predetermined from a treatment plan for that target area and the patient. Shielding is provided to protect staff administering the treatment and non-target areas from harmful levels of radiation exposure. The radiotherapy applicator system is reusable for multi-session treatment and may be provided as a customized kit.

A body-insertable device having an adjustable radiation emission direction and radiation emission range, which includes a first outer body extending to be long and an accommodation space having a first accommodation space and a second accommodation space having different distances to the first outer body.