Disclosed herein are methods for patient setup and patient target region localization for the irradiation of multiple patient target regions in a single treatment session. Virtual localization is a method that can be used to register a patient target region without requiring that the patient is physically moved using the patient platform. Instead, the planned fluence is updated to reflect the current location of the patient target region by selecting a localization reference in the localization image, calculating a localization function based on the localization reference point, and calculating the delivery fluence by convolving the localization function with a shift-invariant firing filter. Mosaic multi-target localization partitions a planned fluence map for multiple patient target regions into sub-regions that can be individually localized. De-coupled multi-target localization involves generating a separate planned fluence map for each target but constraining a cumulative fluence map to ensure dosimetric goals are met.

A method of beam angle optimization for an IMRT radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the DCS, evaluating a respective beam's eye view (BEV) score of each pixel of a BEV plane using the doses of the one or more ROIs, determining one or more BEV regions in the BEV plane based on the BEV scores, determining a BEV region connectivity manifold based on the BEV regions, and determining a set of IMRT fields based on the BEV region connectivity manifold.

An example method of treating a target using particle beam includes directing the particle beam along a path at least part-way through the target, and controlling an energy of the particle beam while the particle beam is directed along the path so that the particle beam treats at least interior portions of the target that are located along the path. While the particle beam is directed along the path, the particle beam delivers a dose of radiation to the target that exceeds one (1) Gray-per-second for a duration of less than five (5) seconds. A treatment plan may be generated to perform the method.

A photon source emits a flattening filter-free photon beam. A control circuit operably couples to a multi-layer multi-leaf collimator that is disposed between the photon source and a treatment area of a patient. The control circuit automatically arranges operation of some, but not all, of the layers of the multi-layer multi-leaf collimator to serve as a virtual flattening filter with respect to the flattening filter-free photon beam emitted by the photon source. By one approach, another of the layers of the multi-layer multi-leaf collimator serves to form a treatment aperture corresponding to a shape of the treatment area of the patient. By one approach the control circuit comprises an integral part of a treatment platform (as versus a dedicated treatment planning platform) and can carry out most or even essentially all of the planning steps that lead to administration of the treatment to a patient.

A radiation system is provided. The radiation system may include a bore accommodating an object, a rotary ring, a first radiation source and a second radiation source mounted on the rotary ring and a processor. The first radiation source may be configured to emit a first cone beam toward a first region of the object. The second radiation source may be configured to emit a second beam toward a second region of the object, the second region including at least a part of the first region. The processor may be configured to obtain a treatment plan of the object, the treatment plan including parameters associated with radiation segments. The processor may be further configured to control an emission of the first cone beam and/or the second beam based on the parameters associated with the radiation segments to perform a treatment and a 3-D imaging simultaneously.

An example particle therapy system includes a particle accelerator to output a particle beam having a spot size; a scanning system for the particle accelerator to scan the particle beam in two dimensions across at least part of a treatment area of an irradiation target; and an adaptive aperture between the scanning system and the irradiation target. The adaptive aperture includes structures that are movable relative to the irradiation target to approximate a shape to trim part of the treatment area. The part of the treatment area has a size that is based on an area of the spot size.

The present disclosure may provide a radiation system. The radiation system may include a treatment head, a detector, a plurality of imaging sources, and a gantry. The treatment head, the detector, and the plurality of imaging sources may be mounted on the gantry. The treatment head may be configured to deliver a treatment beam toward an object. The plurality of imaging sources may be configured to deliver a plurality of imaging beams toward the object. At least two of the plurality of imaging sources may share the detector. The detector may be configured to detect at least two of the plurality of imaging beams. The detected at least two imaging beams may be emitted by different imaging sources of the at least two imaging sources.

A method of measuring a rotational position of an assembly with circumferential ferromagnetic teeth includes applying an excitation signal for a cycle to an actuator, the cycle causing a first rotational displacement of a first ferromagnetic tooth from a first rotational position to a second rotational position and a second rotational displacement of a second ferromagnetic tooth from the second rotational position to a third rotational position. The method further includes measuring a plurality of first signal outputs from a magnetoresistive sensor during the cycle; determining one or more signal offset values based on the plurality of first signal outputs; applying the signal excitation for a portion of a second cycle to the actuator; measuring second signal outputs from the magnetoresistive sensor; generating corrected signals by modifying the second signal outputs with the signal offset values; and, based on the corrected signals, determining a rotational position of the assembly.

A multileaf collimator includes a plurality of movable leaves for shaping a radiotherapy beam, wherein each leaf is independently movable in a same linear travel direction. Each leaf includes a linear array of magnets disposed on a measurement surface of the leaf and an array of magnetoresistive sensors that is disposed proximate the measurement surfaces of the leaves.

The invention is to provide a radiation therapy system capable of widening a radiation irradiation range to a patient without increasing a burden on a structure. The radiation therapy system includes: a radiation source; a rotation mechanism that supports the radiation source and rotates the radiation source around an isocenter; a couch that places a therapy target site of a patient at the isocenter; a head swing mechanism that is disposed between the radiation source and the rotation mechanism and that swings an irradiation axis of a radiation emitted from the radiation source by swinging the radiation source; and a control unit that controls the radiation source, the rotation mechanism, and the head swing mechanism. The control unit holds the head swing mechanism in a state where the irradiation axis of the radiation of the radiation source is shifted from the isocenter in a predetermined direction by a predetermined amount, and rotates the radiation source by the rotation mechanism while emitting the radiation from the radiation source while maintaining the state of the head swing mechanism.