Devices, systems, and methods for enhancing MRI image quality and tracking accuracy in MR-guided treatment systems are described.

Systems and methods are disclosed for monitoring anatomic position of a human subject and modifying a radiotherapy treatment based on anatomic position changes, as determined with a regression model trained to estimate movement of a region of interest. Example operations for movement monitoring and therapy control include: obtaining 3D image data for a subject, which provides a reference volume and at least one defined region of interest; obtaining real-time 2D image data corresponding to the subject, captured during the radiotherapy treatment session; extracting features from the 2D image data; producing a relative motion estimation of a region of interest with a machine learning regression model, the model trained to estimate a spatial transformation from the 2D image data based on training from the reference volume; and controlling a radiotherapy beam of a radiotherapy machine used in the radiotherapy session, based on the relative motion estimation.

Systems and methods are disclosed for monitoring anatomic position of a human subject for a radiotherapy treatment session, based on use of a regression model trained to estimate movement of a region of interest based on 2D image data input. Example operations for movement estimation include: obtaining 3D image data for a subject, which provides a reference volume and at least one defined region of interest; obtaining 2D image data corresponding to the subject, captured in real time (during the radiotherapy treatment session); extracting features from the 2D image data; analyzing the extracted features with a machine learning regression model, trained to estimate a spatial transformation in the three dimensions of the reference volume; and outputting and using a relative motion estimation of the at least one region of interest, produced from the machine learning regression model, the relative motion estimation being estimated from the extracted features.

A radiotherapy system is configured to determine in vivo dose deposition of a radiotherapy treatment beam. The system includes the following components. A bi-planar magnetic resonance imaging (MRI) apparatus comprising a pair of spaced apart magnets. One of the magnets includes a hole proximal the centre thereof. A treatment beam source configured to generate a radiotherapy treatment beam. The treatment beam source is positioned to transmit the treatment beam through the hole in the magnet. A patient support configured to position a patient with the system so that a treatment target is proximal the treatment beam. A Positron Emission Tomography (PET) detector configured to obtain PET data of the treatment beam impacting the patient. The PET detector is positioned so that a transverse section of the patient that includes the treatment target lies between opposing portions of the PET detector.

A sterilizable device comprising electromagnetic transponders separated from one another by a flexible spacer material enclosed within radiofrequency-transparent sterilizable tubing for target tracking during prostate treatments, and method of use thereof.

A camera monitoring system for a bore based medical apparatus is described, wherein the camera monitoring system comprises a first and a second image sensor mounted on opposing surfaces of a circuit board. The first image sensor is arranged to view an object from a first viewpoint via a first lens arrangement and a first mirror and the second image sensor is arranged to view the object from a second viewpoint via a second lens arrangement and a second mirror. By having the image sensors view an object via the mirrors, via the lens arrangements, the lens arrangements contribute to the effective separation of the first and second viewpoints enabling the size of the housing of the camera to be reduced. Furthermore, a method for calibrating a camera monitoring system in a bore based setup is described and also a configuration of arranging a camera monitoring system in connection with a bore based medical apparatus.

A radiation medical device, including a main support, and a radiation assembly (30) and an imaging assembly (20) respectively located at both ends of the main support. After an imaging scan is completed and pathological tissue positioning pictures are taken, a patient is directly moved to the other end of the main support to allow the radiation assembly (30) to perform radiation therapy to improve the efficiency of the radiation therapy after the completion of pathological tissue positioning, and effectively reduce movement of the patient when the patient is being moved for radiation therapy after the imaging assembly (20) completes pathological tissue positioning, thus reducing pathological tissue positioning error caused by too much movement.

Patient sitting equipment for radiotherapy, including an installation platform, a treatment couch assembly, a support and adjustment assembly and a 3D imaging assembly. The treatment couch assembly is configured to fix a patient. The support and adjustment assembly is configured to adjust a position of the treatment couch assembly with respect to the installation platform. The 3D imaging assembly includes a column assembly and a 3D imaging device. The column assembly is arranged at the installation platform, and extends along the vertical direction. The 3D imaging device is movably arranged at the column assembly, and is corresponding to the treatment couch assembly in a horizontal projection direction. The 3D imaging device is configured to scan the patient.

A radiation system is provided. The radiation system may include a bore accommodating an object, a rotary ring, a first radiation source and a second radiation source mounted on the rotary ring and a processor. The first radiation source may be configured to emit a first cone beam toward a first region of the object. The second radiation source may be configured to emit a second beam toward a second region of the object, the second region including at least a part of the first region. The processor may be configured to obtain a treatment plan of the object, the treatment plan including parameters associated with radiation segments. The processor may be further configured to control an emission of the first cone beam and/or the second beam based on the parameters associated with the radiation segments to perform a treatment and a 3-D imaging simultaneously.

In an example, a signal segment evaluator can be programmed to evaluate a morphology of at least one electrophysiological signal to identify a signal segment of interest. The morphology of the signal segment of interest can be indicative of an electrophysiological event of a patient during a respective time interval. A reconstruction engine can be programmed to reconstruct electrophysiological signals on a surface of interest within a body of the patient based on the electrophysiological signals measured from an outer surface of the patient and geometry data representing an anatomy of the patient. A map generator can be programmed to generate a map representing the reconstructed electrophysiological signals on the surface of interest for the respective time interval of the signal segment of interest. A target generator can be programmed to identify a target site within the patient's body based on the map for the electrophysiological event.