This application relates to methods for delivering radiation to a positron-emitting target within a subject under continuous PET guidance. Instead of directing radiation at a collinear path along each detected positron line-of-response (LOR), the methods generally include detecting a pattern of LORs that intersect the target. In response to the pattern, radiation may be delivered along paths that are not necessarily collinear to any of the LORs. Methods for further modifying radiation delivery as well as the detected LOR population are also described.

Described is a device for radiotherapy treatment with a high dose rate of ionizing radiation, comprising an accelerating guide (11) of a medical radiofrequency accelerator, at least two simultaneously thermostated resonant cavities (10) and comprising a first pick-up (12), a second pick-up (12B) in at least two resonant cavities (10) and an optical system (20) of the beam.

One or more example embodiments of the present invention relates to a tilt module for a patient couch, having a first support unit, a second support unit and a linear drive system, wherein one of the first support unit and the second support unit is configured to fix the tilt module to a stand of the patient couch or to receive a couch board, wherein the second support unit is connected via a joint to the first support unit at a tilt angle, wherein the linear drive system couples the first support unit and the second support unit such that the second support unit is tiltable relative to the first support unit along a circular-like travel path with simultaneous variation of the tilt angle due to a change in length of the linear drive system.

The invention relates to a system for detecting, obtaining images and treating or eliminating tumours, diseases or other anomalies, which is excited by means of X-rays biomarked with metallic nanoparticles and which comprises an external support structure (600) with a shield, which comprises: a confocal system (1000) comprising a shielded external structure (67, 75) that contains a convergent scan X-ray device (100), a detection system (200) for X-ray photons with collimators that are solidly connected to and confocal with the first device, a second convergent treatment device (300) solidly connected to the confocal structure (100 and 200), and a supporting structure (400) that contains the convergent scan X-ray device (100), the detection system (200) and the second convergent treatment device (300), which project to a single focal point, and which ensures that same are confocal; a controlled 3D scanning structure (500) that moves a bed and/or focal point onto which ionising radiation is concentrated; an electronic control system comprising programmable electronics (700) that allow the operation of the convergent beam device, the operation of the sensors (2) and the movements of the 3D scanning system; and a computed tomography (CT) device (2000) comprising collimators, an X-ray tube and sensors and which is incorporated into the structure (600). The invention further relates to an associated method.

Images obtained by a camera system (10) arranged to obtain images of a patient (20) undergoing radio-therapy are processed by a modeling unit (56,58) which generates a model of the surface of a patient (20) being monitored. Additionally the patient monitoring system processes image data not utilized to generate a model of the surface of a patient being monitored to determine further information concerning the treatment of the patient (20). Such additional data can comprise data identifying the relative location of the patient and a treatment apparatus (16). This can be facilitated by providing a number or retro-reflective markers (30-40) on a treatment apparatus (16) and a mechanical couch (18) used to position the patient (20) relative to the treatment apparatus (16) and monitoring the presence and location of the markers in the portions of the images obtained by the stereoscopic camera (10).

Magnetic resonance (MR) guided radiation therapy (MRgRT) enables control over the delivery of radiation based on patient motion indicated by MR imaging (MRI) images captured during radiation delivery. A method for MRgRT includes: simultaneously using one or more radiation therapy heads to deliver radiation and an MRI system to perform MRI; using a processor to determine whether one or more gates are triggered based on at least a portion of MRI images captured during the delivery of radiation; and in response to determining that one or more gates are triggered based on at least a portion of the MRI images captured during the delivery of radiation, suspending the delivery of radiation.

First and second skeleton model data is determined based on first and second surface data of a patient. Each of the skeleton model data describes geometries of rigid anatomic structures of a patient at a different point in time. Skeleton difference data is determined describing differences between the geometries of the rigid anatomic structures. In a next step, movement instruction data is determined which describes movement to be performed by the rigid anatomic structures to minimize the differences, i.e. to correct the posture of the patient. The movement instruction data is for example determined based on anatomy constraint data which describes anatomical movement constraints for the rigid anatomic structures (e.g. range of motion of a joint). An instruction is displayed (e.g. using augmented reality), guiding the user how to move the rigid anatomic structures so as to correct the patients posture.

A system and method for delivering microbeam radiation therapy (MRT) includes a computed tomography scanner (“CT”) configured to generate tomographic images of a subject, or patient, the scanner including an imaging apparatus, a gantry with an opening for positioning the patient therein, an axis of rotation around which the gantry rotates, and an x-ray source mounted to and rotatable with the gantry. The system includes a bed for patient positioning within the gantry opening and a multi-slit collimator removably mounted downstream of the x-ray source for delivering an array of microbeams of MRT to a targeted portion of the patient. Switching between MRT and CT is provided, and MRT modes of operation include a stationary mode, and continuous and step-wise rotational modes.

A tumor positioning method includes obtaining projection images of a tumor at different angles; and registering the projection images with an initial reference image to obtain a first offset. If it is determined that a virtual reacquisition operation needs to be performed according to the first offset, the method further includes generating a first reference image according to the first offset; and registering the projection images with the first reference image to obtain a second offset. If it is determined that the operation does not need to be performed according to the second offset, the method further includes outputting a first accumulated offset being a sum of the first and second offsets. The method may solve problems of long time consuming and the service life of a treatment couch and acquisition devices being reduced due to repeatedly moving the treatment couch and repeatedly acquiring the X-ray projection images.

A computer implemented method for determining a two dimensional DRR referred to as dynamic DRR based on a 4D-CT, the 4D-CT describing a sequence of three dimensional medical computer tomographic images of an anatomical body part of a patient, the images being referred to as sequence CTs, the 4D-CT representing the anatomical body part at different points in time, the anatomical body part comprising at least one primary anatomical element and secondary anatomical elements, the computer implemented method comprising the following steps: acquiring the 4D-CT; acquiring a planning CT, the planning CT being a three dimensional image used for planning of a treatment of the patient, the planning CT being acquired based on at least one of the sequence CTs or independently from the 4D-CT, acquiring a three dimensional image, referred to as undynamic CT, from the 4D-CT, the undynamic CT comprising at least one first image element representing the at least one primary anatomical element and second image elements representing the secondary anatomical elements; acquiring at least one trajectory, referred to as primary trajectory, based on the 4D-CT, the at least one primary trajectory describing a path of the at least one first image element as a function of time; acquiring trajectories of the second image elements, referred to as secondary trajectories, based on the 4D-CT; for the image elements of the undynamic CT, determining trajectory similarity values based on the at least one primary trajectory and the secondary trajectories, the trajectory similarity values respectively describing a measure of similarity between a respective one of the secondary trajectories and the at least one primary trajectory; determining the dynamic DRR by using the determined trajectory similarity values, and, in case the planning CT is acquired independently from the 4D-CT, further using a transformation referred to as planning transformation from the undynamic CT to the planning CT, at least a part of image values of image elements of the dynamic DRR being determined by using the trajectory similarity values.