Disclosed herein are systems and methods for monitoring calibration of positron emission tomography (PET) systems. In some variations, the systems include an imaging assembly having a gantry comprising a plurality of positron emission detectors. A housing may be coupled to the gantry, and the housing may include a bore and a radiation source holder spaced away from a patient scan region within the bore. A processor may be configured to receive positron emission data from the positron emission detectors and to distinguish the positron emission data from the radiation source holder and from the patient scan region. A fault signal may be generated when the positron emission data from the radiation source holder exceeds one or more threshold parameters or criteria.

Systems, devices, and methods for imaging-based calibration of radiation treatment couch position compensations.

In a particle beam irradiation system, upon receipt of a signal to stop irradiation of a charged particle beam, the signal outputted from a scanning controller, an accelerator and transport system controller stops emission of the charged particle beam from a charged particle beam generation unit to the irradiation unit, the scanning controller determines, according to an irradiation dose of the charged particle beam at one of a plurality of spots that has been irradiated with the charged particle beam until immediately before the accelerator and transport system controller stops the emission, the irradiation dose measured by the irradiation dose monitor from when the signal to stop the irradiation is outputted, whether or not to skip the irradiation of the charged particle beam at another one of the plurality of spots subsequent to the one of the plurality of spots, so as to control the accelerator and transport system controller.

A radiation dose rate monitor system includes an emitting electrode configured to be impinged by radiation radiation; a collecting electrode configured to form an electrical circuit with said emitting electrode, a current measurement device configured to measure a current through said emitting and collecting electrodes indicative of a dose of said radiation radiation, and a chamber enclosing a gas. Emission of secondary electrons from the emitting electrode provides a majority of the current.

The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.

A method enables testing and evaluation of an expert human reviewer or an artificial intelligence (AI) error detection engine associated with a radiotherapy treatment planning process. Intentional errors are introduced into the output of a software module or AI engine that performs a certain step in the radiotherapy treatment planning process. The efficacy of the human or AI reviewer in detecting errors can then be evaluated or tested by determining whether the human or AI reviewer has detected the introduced error.

A reconstructed volume of a region of patient anatomy is processed to reduce motion artifacts in the reconstructed volume. Autosegmentation of high-contrast structures present in an initial reconstructed volume is performed to generate a 3D representation of the high-contrast structures. 2D mask projections are generated by performing forward projection on the 3D representation, where each 2D mask projection includes location information indicating pixels that correspond to the high-contrast structures during the forward projection process. The acquired 2D projections are modified via in-painting to generate corrected 2D projections, where the acquired 2D projections are modified using information from the 2D mask projections. For example, pixels in the acquired 2D projections that are associated with high-contrast moving structures are replaced with low-contrast pixels. These corrected 2D projections are used to produce an improved reconstructed volume with fewer and/or less visually prominent motion artifacts.

A radiotherapy system according to an embodiment obtains a distribution of a medicament administered to a tumor, obtains a distribution of a radiation dose administered to the tumor, and produces a radiotherapy plan for the tumor with a combined use of the medicament and the radiation dose based on the medicament distribution and the dose distribution.

Systems and methods for managing motions of an anatomical region of interest of a patient during image-guided radiotherapy are disclosed. An exemplary system may include an image acquisition device, a radiotherapy device, and a processor device. The processor device may be configured to control the image acquisition device to acquire at least one 2D image. Each 2D image may include a cross-sectional image of the anatomical region of interest. The processor device may also be configured to perform automatic contouring in each 2D image to extract a set of contour elements segmenting the cross-sectional image of the anatomical region of interest in that 2D image. The processor device may be further configured to match the set of contour elements to a 3D surface image of the anatomical region of interest to determine a motion of the anatomical region of interest and to control radiation delivery based on the determined motion.

Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric ganglion, the aorticorenal ganglion and the aortic plexus. Planning of radiosurgical treatments will optionally employ a graphical representation of a blood/tissue interface adjacent these targets.