Systems and methods arc disclosed for generating radio-therapy treatment machine parameters based on projection images of a target anatomy. The systems and methods include receiving an image depicting an anatomy of a subject: generating a first projection image based on the received image that represents a view of the anatomy from a first gantry angle of tire radiotherapy treatment machine; applying a machine learning model to the first projection image to estimate a first graphical aperture image representation of multi-leaf collimator (MLC) leaf positions at the first gantry angle and the radiation intensity at that angle, the machine learning model being trained to establish a relationship between projection images representing different views of a patient anatomy and respective graphical aperture image representations of the MLC leaf positions at different gantry angles corresponding to the different views: and generating radiotherapy treatment machine parameters based on the first graphical aperture image representation.

In particle beam irradiation equipment, a control unit causes a storage unit to store, as position information of reference positions, position information of electromagnets that is acquired at the time of their first alignment, by cameras, and then acquires displacement amounts, based on the position information of the reference positions stored in the storage unit and from position information of the electromagnets acquired at the time of their realignment, by the cameras.

A method includes detecting a potential setup error in a radiation treatment delivery session of a radiation treatment delivery system, wherein the setup error corresponds to a change in a current position of a treatment target relative to a prior position of the treatment target, and wherein the change includes a rotation relative to the prior position of the treatment target. The method further includes modifying, by a processing device, one or more planned leaf positions of a multileaf collimator (MLC) of a linear accelerator (LINAC) of the radiation treatment delivery system to compensate for the potential setup error corresponding to the rotation of the prior position of the treatment target.

Some embodiments are directed to a radiation dosage monitoring system including a model generation module configured to generate a 3D surface model of a portion of a patient undergoing radiation treatment, an image detector configured to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due to the initial Cherenkov radiation emitted from the patient, a processing module configured to determine estimations of radiation applied to the patient utilizing the images from the image detector and the 3D model, and to utilize the determined estimations of radiation applied to the patient together with data indicative of the orientation of a radiation beam inducing emission of the Cherenkov radiation at a time when the radiation beam was applied to generate a 3D internal representation of the location of the portions of a irradiated patient resulting in the emission of the Cherenkov radiation.

Systems and methods for using electronic portal imaging devices (EPIDs) as absolute radiation beam measuring devices and as radiation beam alignment devices without implementation of elaborate and complex calibration procedures.

A position-sensitive ionizing-particle radiation counting detector includes a first substrate and a second substrate generally parallel to the first substrate and forming a gap with the first substrate, with a discharge gas contained within the gap. The detector includes a first electrode electrically coupled to the second substrate, and a second electrode electrically coupled to the first electrode and defining at least one pixel with the first electrode. The detector further includes an open dielectric structure pattern layered over one of the first or second electrodes and a current-limiting quench resistor coupled in series to one of the first or second electrodes. The detector further includes a power supply coupled to one of the first or second electrodes and a first discharge event detector circuitry coupled to the one of the first or second electrodes for detecting a gas discharge counting event in the electrode.

Embodiments of the present invention provide phantoms, and associated methods of calibration which are suitable for use in both medical resonance imaging and radiographic imaging systems. A phantom for calibration of a medical imaging system, comprises a first component having a first outer shape, a portion of which defines part of at least one pocket; and a second component coupled to the first component and having a second outer shape, a portion of which defines another part of the at least one pocket. At least one of the first and second components comprises a reservoir, the reservoir having a shape at least a portion of which locates a center of the at least one pocket.

A method for estimating a spatial distribution of the hazardousness of radiation doses for individuals evolving in a medical operating room defining a three-dimensional environment surrounding at least one source of radiation. First a three-dimensional model of the environment is obtained. Then a simulation of radiation doses attributable to ionizing radiation emitted from the source and scattered by the environment is computed in the model. Then, an image indicating the spatial distribution of the hazardousness for an individual of the radiation doses is generated and displayed. The three-dimensional model comprises models of individuals when the individuals are present in the environment and the image is a three-dimensional image generated for at least a portion of the model including said models of individuals.

A water tank apparatus for use with a radiotherapy system, comprising a base, side walls, end walls, and a top wall, together defining a tank structure, wherein an aperture is defined in the top wall near one end wall, and an upstanding rim surrounding the aperture; and a sensor mounting body fixed within the tank structure, and having formations by which a radiation sensor can be located in a fixed position within the tank structure so as to detect radiation at a point equidistant from the side wall and top wall and base.

The present invention relates to advanced Cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images. In particular, the present invention provides a system and method for simple, accurate, quick, robust, real-time, water-equivalent characterization of beams from LINACs and other systems producing external-therapy radiation for purposes including optimization, commissioning, routine quality auditing, R&D, and manufacture. The present invention also provides a system and method for rapid and economic characterization of complex radiation treatment plans prior to patient exposure. Further, the present invention also provides a system and method of economically detecting Cherenkov radiation emitted by tissue and other media in real-world clinical settings (e.g., settings illuminated by visible light).