A microwave power control device can include: a microwave signal generator and a signal distribution circuitry connected to the microwave signal generator. The microwave signal generator is configured to generate microwave signals and transmit the microwave signals to the signal distribution circuitry; and the signal distribution circuitry is configured to distribute the microwave signals to n accelerating tubes according to a target microwave power distribution ratio, n being an integer greater than or equal to 2.

These teachings provide for accessing optimization information comprising at least one isocenter that corresponds to a body outline for a particular patient, field geometry information for a particular radiation treatment platform, and dosimetric data. The optimization information can further comprise a model of a body outline for the patient. A control circuit optimizes a radiation treatment plan as a function of the optimization information to provide an optimized radiation treatment plan where radiation dose levels delivered to the particular patient from a particular field depends on the relative volume magnitude of field path intersections to thereby reduce radiation dose delivery to healthy patient tissue in regions having relatively more overlapping fields.

The transverse intensity distribution of a beam of x-rays or other radiation can be modulated with a multi-slit collimator device that includes one or more sets of collimator leaves arranged in a one-dimensional array and individually movable to form slits of variable width between pairs of adjacent collimator leaves. A two-dimensional intensity distribution may be achieved using multiple sets of one-dimensionally arranged leaves, e.g., by stacking them along the beam in different orientations, or by stacking them in a transverse direction to form a two-dimensional array of leaves. In some embodiments, the multi-slit collimator device also serves beam-monitoring purposes.

Systems and methods are disclosed for monitoring anatomic position of a human subject and modifying a radiotherapy treatment based on anatomic position changes, as determined with a regression model trained to estimate movement of a region of interest. Example operations for movement monitoring and therapy control include: obtaining 3D image data for a subject, which provides a reference volume and at least one defined region of interest; obtaining real-time 2D image data corresponding to the subject, captured during the radiotherapy treatment session; extracting features from the 2D image data; producing a relative motion estimation of a region of interest with a machine learning regression model, the model trained to estimate a spatial transformation from the 2D image data based on training from the reference volume; and controlling a radiotherapy beam of a radiotherapy machine used in the radiotherapy session, based on the relative motion estimation.

A radiation delivery system that includes a gantry to extend along one or more axes. The gantry is to provide a continuous rotation. The radiation delivery system includes a linear accelerator (LINAC) coupled to the gantry. The LINAC is to generate a treatment beam. The radiation delivery system includes a rotary joint coupled to the gantry. The rotary joint provides a physical connection from the LINAC to an external system that is positioned off the gantry. The physical connection is to transport radio frequency (RF) power.

Apparatuses (devices, systems) and methods for shielding (protecting) surroundings around periphery of regions of interest located inside objects (e.g., patients) from radiation emitted by X-ray systems towards the objects. Apparatus includes: at least one radiation shield assembly including a support base connectable to an X-ray system radiation source or detector, and a plurality of radiation shield segments sequentially positioned relative to the support base, thereby forming a contiguous radiopaque screen configured for spanning around the region of interest periphery with a radiopaque screen edge opposing the object. Radiation shield segments are individually, actively controllable to extend or contract to selected lengths with respective free ends in directions away from or towards the support base(s), for locally changing contour of the radiopaque screen edge. Applicable for shielding (protecting) medical personnel, and patients, from exposure to X-ray radiation during medical interventions or/and diagnostics.

The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.

A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.

A computer-implemented method for a radiation therapy system includes: acquiring a first X-ray image of a region while the region is in a first location, the gantry is in a first imaging position, and a center axis of an imaging beam passes through an isocenter of the radiation therapy system along a first imaging path; acquiring a second X-ray image of the region while the region of patient anatomy is in the first location, the gantry is in a second imaging position, and the center axis of the imaging beam passes through the isocenter along a second imaging path, wherein an angle between the first imaging path and the second imaging path is a non-orthogonal angle; and based on the first X-ray image, the second X-ray image, and a three-dimensional treatment planning image of the region, determining an offset between a planning location for the region and the first location.

The radiographic imaging apparatus is configured so that an irradiation device is mounted on a rotary drum of a rotary gantry. A pair of X-ray sources is disposed outside the rotary drum and attached to the outer surface of the rotary drum. A pair of FPDs facing the respective X-ray sources is mounted in the irradiation device. When X-rays are irradiated, X-ray intensity information is calculated by a signal processing device based an output signal from each radiation detection element of each FPD, and stored in a memory. Based on FOV information set by an input device, an X-ray intensity acquisition device acquires multiple pieces of X-ray intensity information that are calculated based on the output signals from the radiation detection elements in small FOV areas (or large FOV areas) of the FPDs, which are included in the X-ray intensity information stored in the memory.