A radiation system is provided. The radiation system may include a bore accommodating an object, a rotary ring, a first radiation source and a second radiation source mounted on the rotary ring and a processor. The first radiation source may be configured to emit a first cone beam toward a first region of the object. The second radiation source may be configured to emit a second beam toward a second region of the object, the second region including at least a part of the first region. The processor may be configured to obtain a treatment plan of the object, the treatment plan including parameters associated with radiation segments. The processor may be further configured to control an emission of the first cone beam and/or the second beam based on the parameters associated with the radiation segments to perform a treatment and a 3-D imaging simultaneously.

Systems and methods for shuttle mode radiation delivery are described herein. One method for radiation delivery comprises moving the patient platform through the patient treatment region multiple times during a treatment session. This may be referred to as patient platform or couch shuttling (i.e., couch shuttle mode). Another method for radiation delivery comprises moving the therapeutic radiation source jaw across a range of positions during a treatment session. The jaw may move across the same range of positions multiple times during a treatment session. This may be referred to as jaw shuttling (i.e., jaw shuttle mode). Some methods combine couch shuttle mode and jaw shuttle mode. Methods of dynamic or pipelined normalization are also described.

The disclosure provides systems and methods for adjusting a multi-leaf collimator (MLC). The MLC includes a plurality of cross-layer leaf pairs, each cross-layer leaf pair of the plurality of cross-layer leaf pairs includes a first leaf located in a first layer of leaves and a second leaf opposingly located in a second layer of leaves. For at least one cross-layer leaf pair, an effective cross-layer leaf gap to be formed between the first leaf and the second leaf may be determined; at least one of the first leaf or the second leaf may be caused to move to form the effective cross-layer leaf gap; and an in-layer leaf gap may be caused, based on the effective cross-layer leaf gap, to be formed between the first leaf and an opposing first leaf in the first layer. A size of the in-layer leaf gap may be no less than a threshold.

The present application relates to a radiotherapy apparatus for delivering radiation to a subject. The apparatus comprises a source of radiation configured to rotate about an isocenter and emit radiation in a radiation plane containing said isocentre. The apparatus also comprises a subject support surface including a portion configured to be located substantially at the isocenter. The subject support surface comprises a subject support surface rotation mechanism configured to rotate the subject support surface about an axis of rotation parallel to and spaced from an axis that passes through the isocenter. The subject support surface also comprises a first section configured to move from a first position to a second position along at least one of a longitudinal and lateral direction. The apparatus also comprises a processor configured to control the longitudinal and/or lateral movement of the first section as a function of the rotation of the subject support surface to maintain the portion of the subject support surface substantially at the isocenter.

It is provided a method for determining arc costs. The method comprises the steps of: determining a plurality of beam orientations; evaluating a set of at least one cost function comprising an intermediate exposure cost function that is evaluated by performing the substeps of: projecting the at least one target volumes on a beam plane; determining an alignment angle based on a collimator angle value; finding any intermediate area in the beam plane along the alignment angle between areas of the at least one target volume projection; determining a value of the intermediate exposure cost function. The method further comprises the steps of: finding a plurality of arcs, wherein each arc comprises a sequence of a plurality of beam orientations; and calculating, for each arc in the plurality of arcs, at least one arc cost based on the cost function values of the beam orientations of the arc.

A method for EPID-based verification, correction and minimization of the isocenter of a radiotherapy device includes the following: Positioning a measurement body; applying an irradiation field; capturing a common dose image of the measurement body; creating a dose profile on the basis of the captured dose image; determining an inflection point in a plot of the dose profile; linking positions of the inflection points to bodily limits of the measurement body; determining position of a center point of the measurement body relative to an EPID-center; determining a differential vector from a deviation in position of the center point of the measurement body from the EPID-center and from a deviation in position of the field center point of the irradiation field from the EPID-center; and correcting the current radiological isocenter.

Systems and methods relate to multi-modal imaging of tissue combined with highly focused radiation interventions. The system is a portable multimodal imaging unit that integrates imaging and image analysis. The system can be retrofitted to use with any commercial radiation therapy machine. In one aspect, a system integrates various imaging modalities into a single, coordinated structure. The system integrates X-ray and cone beam computed tomography (CBCT), optical imaging (such as bioluminescent imaging (BLI), fluorescence tomography (FT)), and positron emission tomography (PET) imaging in a single, self-contained structure.

Embodiments of the present invention describe systems and methods for providing proton therapy treatment using a beam line where the ESS is reduced or eliminated. For multi-room configurations, a beam line is included having quadrupole and steerer magnets to align and focus a particle beam extracted by an accelerator and guided by a bend section. A degrader is disposed between the bend section and the treatment room, and the energy analyzing functionality is performed by the gantry.

Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a graphical user interface for display on a screen associated with a radiotherapy machine, wherein the graphical user interface contains a page corresponding to one or more stages of radiotherapy treatment for the patient, and transitioning, by the server, the graphical user interface from a first page representing a first stage to a second page representing a second stage provided that at least a predetermined portion of tasks associated with the first stage has been satisfied.

Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 μsec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.4×10{circumflex over ( )}−6cGy/bunch.