Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.

An apparatus comprising a radiation source, coincident positron emission detectors configured to detect coincident positron annihilation emissions originating within a coordinate system, and a controller coupled to the radiation source and the coincident positron emission detectors, the controller configured to identify coincident positron annihilation emission paths intersecting one or more volumes in the coordinate system and align the radiation source along an identified coincident positron annihilation emission path.

The disclosure provides a radiotherapy system, comprising: a bed, for supporting the patient; and a bridge, comprising one or more rolling elements for supporting the bed and allowing the bed to be moved along a surface of the bridge. The one or more rolling elements are located at respective fixed positions in the bridge.

System for treatment positioning is provided. The system may include a treatment component, an imaging component, and a couch. The treatment component may include a radiation source that has a radiation isocenter. The couch may be movable between the treatment component and the imaging component, and include a positioning line that has a positioning feature. The system may acquire at least one first image relating to a subject and the positioning line using the radiation source at a set-up position. The system may also acquire at least one second image relating to the subject and the positioning line using the imaging component at an imaging position. The system may further determine a treatment isocenter of a target of the subject based on the at least one second image, and determine a treatment position of the subject based on the first image(s), the second image(s), and the positioning line.

A radiotherapy head can include an electron accelerator, a deflection control assembly, a collimator, and a target material. The deflection control assembly is provided between the electron accelerator and the collimator, the collimator is provided with a plurality of collimating holes, and the target material is provided at an entrance of the each of the plurality of collimating holes; the deflection control assembly is configured to adjust a deflection angle of electron beams emitted by the electron accelerator, and emit angle-deflected electron beams to the target material; the target material is configured to convert the electron beams emitted to the target material into X-rays; and the collimator is configured to project the X-rays to a target via the plurality of collimating holes.

The present disclosure lies in the field of medical radiotherapy and relates to an applicator for a medical radiotherapy device, an applicator system for a medical radiotherapy device and a method for using an applicator or an applicator system. The applicator includes an applicator head and an applicator body. The applicator head and the applicator body are embodied such that the applicator head can be assembled on, and disassembled from, the applicator body, in each case without damage.

An imaging apparatus includes a first X-ray detector that includes: a low energy scintillator operable to convert an incident X-ray spectrum into a first set of light photons; a first light imaging sensor operable to generate a set of low energy image signals from the first set of light photons, wherein a first exit radiation is a remainder portion of the first incident radiation after the X-ray spectrum passes through the low energy scintillator and the first light imaging sensor; an energy-separation filter operable to absorb or reflect at least a portion of the energy of the first exit X-ray spectrum and convert the first exit X-ray spectrum into a second exit X-ray spectrum; a second X-ray detector that includes: a high energy scintillator operable to convert the second exit X-ray spectrum into a second set of light photons; a second light imaging sensor operable to generate a set of high energy image signals from the second set of light photons; and a processor configured to: generate a high-energy image that is based on the set of high energy image signals and a low-energy image that is based on the set of low energy image signals; and perform a comparison of the high-energy image from the low-energy image to generate a soft tissue image.

The present system and method for simulating particles and waves is useful for calculations involving nuclear and full spectrum radiation transport, quantum particle transport, plasma transport and charged particle transport. The invention provides a mechanism for creating accurate invariants for embedding in general three-dimensional problems and describes means by which a series of simple single collision interaction finite elements can be extended to formulate a complex multi-collision finite element.

An apparatus comprising a radiation source, coincident positron emission detectors configured to detect coincident positron annihilation emissions originating within a coordinate system, and a controller coupled to the radiation source and the coincident position emission detectors, the controller configured to identify coincident positron annihilation emission paths intersecting one or more volumes in the coordinate system and align the radiation source along an identified coincident positron annihilation emission path.

Systems and methods for the automatic generation and optimization of radiation therapy treatment plans, and systems and methods for the automatic generation and optimization of an adapted plan in an adaptive radiation therapy workflow.