The present disclosure is directed to a radiation therapy system. The radiation therapy system may comprise a magnetic resonance imaging (MRI) apparatus configured to acquire MRI data with respect to a region of interest (ROI) of a subject, the MRI apparatus including a magnetic body; and a radiation therapy apparatus configured to apply a radiation beam to at least one portion of the ROI. The radiation therapy apparatus may include a linear accelerator configured to accelerate electrons to produce the radiation beam, the linear accelerator being located in a bore formed by an inner surface of the magnetic body, and a length direction of the linear accelerator being parallel with an axis of the magnetic body.

Disclosed are an oral fixation device for radiation therapy and an oral fixation method in treatment of a lip cancer. The oral fixation device for radiation therapy includes a first spacer including a first insert inserted between a first lip portion and a first gum portion, and a tooth support coupled to the first spacer at a side of the first spacer disposed inwardly of an oral cavity, wherein teeth or gums of a patient is supported on the tooth support, wherein a first spacer has a specific thickness to maintain a specific spacing between the first lip portion and the first gum portion, wherein the first lip portion includes a treatment target portion to be subjected to the radiation therapy.

The invention provides a radiotherapy system and a method for controlling safety interlock thereof. The radiotherapy system includes a beam generating apparatus, which includes a charged particle beam generating apparatus and a neutron beam generating portion interacting with a charged particle beam generated by the charged particle beam generating apparatus to generate a therapeutic neutron beam to irradiate into a first irradiation chamber. In operation, the radiotherapy system determines whether there is a safety problem by a beam control module according to the received operation data of the charged particle beam generating apparatus or by a system control module according to the received operation data of the radiotherapy system, and the beam control module or the system control module controls the charged particle beam generating apparatus through the beam control module, to generate the charged particle beam or not, or interact with the neutron beam generating portion.

The present disclosure relates to a radiation shield device comprising a sheet of material comprising a plurality of flaps, wherein the sheet comprises a barrier to ionizing radiation. The present disclosure also relates to a method for manufacturing said radiation shield device.

A particle beam adjustment device includes: a position monitor that detects a positional deviation of a particle beam transported from a beam transport section; an interlock device to interrupt irradiation of the particle beam when a positional deviation of the particle beam is detected by the position monitor; a pair of screen monitors that measure position and angle of an axis of the particle beam; a correction electromagnet that controls the axis of the particle beam by adjusting a magnetic field on a basis of a signal indicating the particle beam position and angle measured by the screen monitors; and a beam scanning electromagnet that irradiates an irradiation target with the particle beam. One of the screen monitors is installed outside a treatment room, and the other screen monitor and the position monitor are installed inside the treatment room.

Conventional single fraction 20-Gy broadbeam photonbeam or protonbeam chemo-radiosurgery does not sterilize EMT-MET cancer stem cell radiodurans but single fraction 100 to 10,000 Gy microbeam radiosurgery sterilizes them. Device and methods for microbeam chemo-radiosurgery including 250 MeV wakefield electronbeam is disclosed.

Surgery, chemotherapy and broadbeam and microbeam radiosurgery releases billions of abscopal metastasis causing, tumor specific plasma soluble proteins, cell membranes, apoptotic bodies, DNA and RNAs, exosomes like telomere-telomerase, ATM-ATM kinase and others. They and adaptive resistance to chemo-radiosurgery, paraneoplastic and non-paraneoplastic diseases causing immune complexes are removed by pulse flow combined continuous flow ultracentrifugation apheresis and immune affinity chromatography. Chemotherapy and high dose radiation exposed tumor cells and their exosomes are made sensitive to telomerase inhibiting and apoptosis inducing and least toxic epigallocatechin and to heparin bound receptors. They convert triple negative breast tumors into receptor positive tumors which open new avenues for treating most aggressive breast cancers.

A portable device for insertion of radioactive seeds in percutaneous interstitial brachytherapy applications is described. The device includes: an elongated main body in form of a handpiece; a shielded container of radioactive seeds, received within the main body and having a rotating drum suitable, in use, to release one or more radioactive seeds from the container; means for driving the rotating drum, activatable by an operator and based on lever mechanisms and gears; and means for introducing one or more radioactive seeds in a body site of interest, comprising a substantially wire-shaped pusher. The pusher urges the radioactive seed(s) released from the rotating drum through a cannula unit.

Systems and methods for providing a real time visualization of scattered radiation in a medical facility are provided. A number of visualization devices such as augmented reality (“AR”) tracking devices, electronic displays, or projection devices are in electronic communication with a controller and configured to generate a visualization of scattered radiation. Position data is received from the position sensors associated with individuals in the medical facility, the AR tracking devices, radiation producing medical equipment, or radiation scattering medical equipment, and the visualization is adjusted accordingly.

Apparatuses (devices, systems) and methods for shielding (protecting) surroundings around periphery of regions of interest located inside objects (e.g., patients) from radiation emitted by X-ray systems towards the objects. Apparatus includes: at least one radiation shield assembly including a support base connectable to an X-ray system radiation source or detector, and a plurality of radiation shield segments sequentially positioned relative to the support base, thereby forming a contiguous radiopaque screen configured for spanning around the region of interest periphery with a radiopaque screen edge opposing the object. Radiation shield segments are individually, actively controllable to extend or contract to selected lengths with respective free ends in directions away from or towards the support base(s), for locally changing contour of the radiopaque screen edge. Applicable for shielding (protecting) medical personnel, and patients, from exposure to X-ray radiation during medical interventions or/and diagnostics.

New techniques for controlling electromagnetic and other forms of radiation are provided. In some aspects of the invention, multiple sources of radiation with characteristics that are projected to constructively interfere at a target are provided. In other aspects, spatially-encoded source signals create a decrypted resulting beam at a planned, target location. In still other aspects, a variable shield which is also a lens is inserted between a radiation target and collateral material.