An example particle therapy system includes a particle beam output device to direct output of a particle beam; a treatment couch to support a patient containing an irradiation target, with the treatment couch being configured for movement; a movable device on which the particle beam output device is mounted for movement relative to the treatment couch; and a control system to provide automated control of at least one of the movable device or the treatment couch to position at least one of the particle beam or the irradiation target for treatment of the irradiation target with the particle beam and, following the treatment of the irradiation target with the particle beam, to provide automated control of at least one of the movable device or the treatment couch to reposition at least one of the particle beam or the irradiation target for additional treatment of the irradiation target with the particle beam.

A particle beam radiotherapy system has been proposed by using a set of first and second scatterers, whereby a short-duration pulse beam is irradiated to a lesion. When the duration of the radiotherapy beam is 200 milliseconds or less, healthy tissues are selectively protected and only cancer tissues are damaged. For example, it can be used for cancer treatment of brain metastases that may be distributed throughout the entire brain tissues. The positions of the scatterers and the energy of the incident particle beams are optimized according to the position and the volume of the brain tissues.

The present disclosure generally relates to an applicator for radiotherapy and a method for determining a thickness of a scattering foil and modulator therein. According to one embodiment, an applicator for radiotherapy may comprise a housing having a hollow structure with an opening, a scattering foil disposed at an opening of the hollow structure and configured to receive a first radiation and convert a portion of the first radiation into a second radiation while scattering the first radiation, and a modulator disposed inside the hollow structure and configured to modulate an intensity of mixed radiation including the first radiation and the second radiation.

An x-ray imaging apparatus and associated methods are provided to execute multi-pass imaging scans for improved quality and workflow. An imaging scan can be segmented into multiple passes that are faster than the full imaging scan. Data received by an initial scan pass can be utilized early in the workflow and of sufficient quality for treatment setup, including while the another scan pass is executed to generate data needed for higher quality images, which may be needed for treatment planning. In one embodiment, a data acquisition and reconstruction technique is used when the detector is offset in the channel and/or axial direction for a large FOV during multiple passes.

Methods and systems for correcting position errors for a multi-leaf collimator (MLC) are provided. A method may include determining a first position for each of the plurality of leaves. The information associated with the first position may include a first movement direction and a first angle. A movement of the each of the plurality of leaves along the first movement direction may be configured to move toward or away from a center of the radiation field. The method may also include determining an offset value associated with the first position based on the first angle and the first movement direction; and determining a target position of the each of the plurality of leaves based on the offset value.

A variable thickness energy selection system for use in a charged particle therapy system is arranged within the nozzle housing downstream of monitoring systems, such as a dose monitor and spot position monitor. This positions the energy selection system proximal to the patient. The thickness of an absorber within the energy selection system can be varied quickly without requiring the ion beam to be turned off between energy selections, thereby allowing for rapid control of the energy selection of the ion beam. The absorber may include one or more high density solid absorbers, or a high-density liquid absorber contained in a closed fluid dynamic system that includes an enclosure positioned within the beam path and a reservoir positioned outside of the beam path.

Disclosed herein are systems and methods for monitoring calibration of positron emission tomography (PET) systems. In some variations, the systems include an imaging assembly having a gantry comprising a plurality of positron emission detectors. A housing may be coupled to the gantry, and the housing may include a bore and a radiation source holder spaced away from a patient scan region within the bore. A processor may be configured to receive positron emission data from the positron emission detectors and to distinguish the positron emission data from the radiation source holder and from the patient scan region. A fault signal may be generated when the positron emission data from the radiation source holder exceeds one or more threshold parameters or criteria.

An x-ray imaging apparatus and associated methods are provided to receive measured projection data in a primary region and measured scatter data in asymmetrical shadow regions and determine an estimated scatter in the primary region based on the measured scatter data in the shadow region(s). The asymmetric shadow regions can be controlled by adjusting the position of the beam aperture center on the readout area of the detector. Penumbra data may also be used to estimate scatter in the primary region.

The present disclosure discloses a laser verification apparatus employed in a radiotherapeutic device which comprises a plurality of radioactive sources, a collimator comprising a plurality of collimating holes, and a couch. The radioactive sources are capable of aligning in respect to the collimating holes respectively. The laser verification apparatus comprises: a positioning plate, fixed on the multi-source radiotherapy equipment and arranged between the radiation sources and the collimators; a movable plate, arranged on and movable relative to the positioning plate, and provided with a plurality of first mounting holes and a plurality of second mounting holes, which are arranged one by one, alternately, the movable plate is configured to switch the plurality of first mounting holes or the plurality of second mounting holes to positions corresponding to the plurality of collimators; a plurality of laser emitters respectively received in the second mounting holes, and an acquisition analyzer arranged on the couch and configured to acquire the light beams emitted by the laser emitters and perform data analysis.

The present disclosure provides a system and method for X-ray imaging. The method of calculating scatter in an X-ray image may include forming a modulated X-ray image. The method of forming the modulated X-ray image may include acquiring X-rays through a collimator module and an imaged object in sequence to generate an X-ray image group; the acquisition may be performed during a movement of the collimator module in a first direction and the X-ray image group may include a plurality of X-ray images acquired at different times during the movement of the collimator; extracting sub-zones from the plurality of X-ray images in the X-ray image group; combining the sub-zones in the first direction to form the modulated X-ray image. In the present disclosure, an intensity distribution of the X-rays may be adjusted flexibly using a collimator without adding any extra hardware. In addition, scatter components in the X-ray images may be calculated to eliminate the scatter in the X-ray images finally.