Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.

Methods, systems, and apparatus, including computer programs encoded on computer storage medium, to facilitate interception of messages that include offensive content. In one aspect, a method includes actions of receiving input on a user device that includes message content, determining, on the user device, whether the message content includes offensive content, and in response to determining, on the user device, that the message content includes offensive content, generating an alert message for display on the user device that provides an indication that the message includes offensive content.

Methods, systems, and apparatus, including computer programs encoded on computer storage medium, to facilitate interception of messages that include offensive content. In one aspect, a method includes actions of receiving input on a user device that includes message content, determining, on the user device, whether the message content includes offensive content, and in response to determining, on the user device, that the message content includes offensive content, generating an alert message for display on the user device that provides an indication that the message includes offensive content.

One or more computing devices, systems, and/or methods for providing a system with access to resources associated with a user account using a disposable email address (DEA) are provided. A request to provide a system with access to a first set of resources may be received. The first set of resources may be associated with a first email account associated with a first email address. A first DEA associated with the first email account may be generated. The first DEA may be transmitted to the system. A first set of modified emails may be generated based upon a first set of emails of the first email account. A first modified email of the first set of modified emails may comprise an indication of the first DEA. Access to the first set of modified emails may be provided to the system. The first DEA may be deactivated.

A system for a graphical user interface for fraud detection for a call center system includes a processor and a visual display in communication with the processor. The processor causes the visual display to present an identifier corresponding to a communication received; a graphical representation of a threat risk associated with the identifier; a numeric score associated with the threat risk, wherein the numeric score is a weighted score based on a plurality of predetermined factors updated substantially continuously.

Techniques for detecting instances of external fraud by monitoring digital activities that are performed with accounts associated with an enterprise are disclosed. In one example, a threat detection platform determines the likelihood that an incoming email is indicative of external fraud based on the context and content of the incoming email. To understand the risk posed by an incoming email, the threat detection platform may seek to determine not only whether the sender normally communicates with the recipient, but also whether the topic is one normally discussed by the sender and recipient. In this way, the threat detection platform can establish whether the incoming email deviates from past emails exchanged between the sender and recipient.

Disclosed are various approaches for validating a relevance or an accuracy associated with an item being attached to a message or inserted inline with the text of the message or other type of document. An addition of the item (e.g., attachment, hyperlink, embedded image, etc.) to the message being generated by a sender can be detected. Message keywords associated with the message content and item keywords associated with the item content can be identified following an analysis of the message content and item content. The message keywords and item keywords can be compared to determine a likelihood of a mismatch between the item and the message. Upon determining a potential mismatch and prior to the message being sent to a recipient, a notification identifying the likelihood of the mismatch is presented to the sender.

Sender Policy Framework (SPF) is a widely used method of distinguishing authorized email from unauthorized email. SPF policies are published into a domain's DNS and then looked up and evaluated by mail receivers. Due to the complexity and limitations of the SPF specification, implementation mistakes and risks are widespread. This problem is compounded by the common practice of nesting SPF policies which introduces hidden risks, particularly exceeding DNS lookup limits. Embodiments of the present disclosure enable new SPF techniques such as selectively inactivating parts of a policy by introducing a virtual-all term, designed to secure against the third-party term inclusions in the policy. When the primary policy is online, the virtual-all term may serve as a terminate policy evaluation much like a traditional “all” term. If the primary policy is offline, a “fail open” may be produced, allowing policy evaluation to proceed into previously inactivated segment of the policy.

Sender Policy Framework (SPF) is a widely used method of distinguishing authorized email from unauthorized email. SPF policies are published into a domain's DNS and then looked up and evaluated by mail receivers. Due to the complexity and limitations of the SPF specification, implementation mistakes and risks are widespread. This problem is compounded by the common practice of nesting SPF policies which introduces hidden risks, particularly exceeding DNS lookup limits. Embodiments of the present disclosure enable new SPF techniques such as selectively inactivating parts of a policy by introducing a virtual-all term, designed to secure against the third-party term inclusions in the policy. When the primary policy is online, the virtual-all term may serve as a terminate policy evaluation much like a traditional “all” term. If the primary policy is offline, a “fail open” may be produced, allowing policy evaluation to proceed into previously inactivated segment of the policy.

Deriving and surfacing insights regarding security threats is disclosed. A plurality of features associated with a message is determined. A plurality of facet models is used to analyze the determined features. Based at least in part on the analysis, it is determined that the message poses a security threat. A prioritized set of information is determined to be provided as output that is representative of why the message was determined to pose a security threat. At least a portion of the prioritized set of information is provided as output.