Disclosed herein is a high throughput optical scanning system to generate super resolution images and methods of use. The optical scanning device and methods of use provided herein can allow high throughput scanning of a continuously moving object with a high resolution despite fluctuations in stage velocity. This can aid in high throughput scanning of a substrate, such as a biological chip comprising fluorophores. Also provided herein are improved optical relay systems and scanning optics.

Devices disclosed herein feature a Wide camera with a Wide field of view (FOV.sub.w), a folded Tele camera with a Tele field of view (FOV.sub.T) smaller than the FOV.sub.w and including an optical path folding element (OPFE). The device may be configured to rotate the OPFE to thereby shift FOV.sub.T relative to FOV.sub.w in response to recognition of an object or subject of interest detected in FOV.sub.w or FOV.sub.T. The device can have high resolution in this overlapping FOV either by fusing the Wide and Tele images or by capturing and saving the Tele image.

Devices disclosed herein feature a Wide camera with a Wide field of view (FOV.sub.w), a folded Tele camera with a Tele field of view (FOV.sub.T) smaller than the FOV.sub.w and including an optical path folding element (OPFE). The device may be configured to rotate the OPFE to thereby shift FOV.sub.T relative to FOV.sub.w in response to recognition of an object or subject of interest detected in FOV.sub.w or FOV.sub.T. The device can have high resolution in this overlapping FOV either by fusing the Wide and Tele images or by capturing and saving the Tele image.

Digital camera comprising an upright Wide camera configured to provide a Wide image with a Wide image resolution and a folded Tele camera configured to provide a Tele image with a Tele image resolution higher than the Wide image resolution, the Wide and Tele cameras having respective Wide and Tele fields of view FOV.sub.W and FOV.sub.T and respective Wide and Tele image sensors, the digital camera further comprising a rotating OPFE operative to provide a folded optical path between an object or scene and the Tele image sensor, wherein rotation of the OPFE moves FOV.sub.T relative to FOV.sub.W. In some embodiments, a rectangular FOV.sub.T is orthogonal to a rectangular FOV.sub.W. When included in a host device having a user interface that displays FOV.sub.T within FOV.sub.W, the user interface may be used to position FOV.sub.T relative to FOV.sub.W, scan FOV.sub.T across FOV.sub.W and acquire, store and display separate Wide and Tele images, composite Wide plus Tele images and stitched Tele images. The positioning of FOV.sub.T within FOV.sub.W, can be done automatically (autonomously) by continuously tracking an object of interest.

Digital camera comprising an upright Wide camera configured to provide a Wide image with a Wide image resolution and a folded Tele camera configured to provide a Tele image with a Tele image resolution higher than the Wide image resolution, the Wide and Tele cameras having respective Wide and Tele fields of view FOV.sub.W and FOV.sub.T and respective Wide and Tele image sensors, the digital camera further comprising a rotating OPFE operative to provide a folded optical path between an object or scene and the Tele image sensor, wherein rotation of the OPFE moves FOV.sub.T relative to FOV.sub.W. In some embodiments, a rectangular FOV.sub.T is orthogonal to a rectangular FOV.sub.W. When included in a host device having a user interface that displays FOV.sub.T within FOV.sub.W, the user interface may be used to position FOV.sub.T relative to FOV.sub.W, scan FOV.sub.T across FOV.sub.W and acquire, store and display separate Wide and Tele images, composite Wide plus Tele images and stitched Tele images. The positioning of FOV.sub.T within FOV.sub.W, can be done automatically (autonomously) by continuously tracking an object of interest.

Digital camera comprising an upright Wide camera configured to provide a Wide image with a Wide image resolution and a folded Tele camera configured to provide a Tele image with a Tele image resolution higher than the Wide image resolution, the Wide and Tele cameras having respective Wide and Tele fields of view FOV.sub.W and FOV.sub.T and respective Wide and Tele image sensors, the digital camera further comprising a rotating OPFE operative to provide a folded optical path between an object or scene and the Tele image sensor, wherein rotation of the OPFE moves FOV.sub.T relative to FOV.sub.W. In some embodiments, a rectangular FOV.sub.T is orthogonal to a rectangular FOV.sub.W. When included in a host device having a user interface that displays FOV.sub.T within FOV.sub.W, the user interface may be used to position FOV.sub.T relative to FOV.sub.W, scan FOV.sub.T across FOV.sub.W and acquire, store and display separate Wide and Tele images, composite Wide plus Tele images and stitched Tele images. The positioning of FOV.sub.T within FOV.sub.W, can be done automatically (autonomously) by continuously tracking an object of interest.

Digital camera comprising an upright Wide camera configured to provide a Wide image with a Wide image resolution and a folded Tele camera configured to provide a Tele image with a Tele image resolution higher than the Wide image resolution, the Wide and Tele cameras having respective Wide and Tele fields of view FOV.sub.W and FOV.sub.T and respective Wide and Tele image sensors, the digital camera further comprising a rotating OPFE operative to provide a folded optical path between an object or scene and the Tele image sensor, wherein rotation of the OPFE moves FOV.sub.T relative to FOV.sub.W. In some embodiments, a rectangular FOV.sub.T is orthogonal to a rectangular FOV.sub.W. When included in a host device having a user interface that displays FOV.sub.T within FOV.sub.W, the user interface may be used to position FOV.sub.T relative to FOV.sub.W, scan FOV.sub.T across FOV.sub.W and acquire, store and display separate Wide and Tele images, composite Wide plus Tele images and stitched Tele images. The positioning of FOV.sub.T within FOV.sub.W, can be done automatically (autonomously) by continuously tracking an object of interest.

Imaging systems and method of optical imaging. One example of an imaging system includes an optical scanning subsystem including an optical source and a MEMS MMA, the MEMS MMA being configured to direct optical radiation generated by the optical source over an area of a scene, a detection subsystem including an optical sensor configured to collect reflected optical radiation from the area of the scene, and a fused fiber focusing assembly including a fused fiber bundle, a plurality of lenses coupled together and positioned to receive and focus the reflected optical radiation from the area of the scene directly onto the fused fiber bundle, a microlens array interposed between the fused fiber bundle and the optical sensor and positioned to receive the reflected optical radiation from the fused fiber bundle, and a focusing lens positioned to direct the reflected optical radiation from the microlens array onto the optical sensor. The MEMS MMA may be further configured to generate and independently steer multiple beams of optical radiation, at the same or different wavelengths, to more fully interrogate the area of the scene. The MEMS MMA through its Piston capability may be further configured to shape the optical beam(s) to execute a variety of optical functions within the beam steering device.

Imaging systems and method of optical imaging. One example of an imaging system includes an optical scanning subsystem including an optical source and a MEMS MMA, the MEMS MMA being configured to direct optical radiation generated by the optical source over an area of a scene, a detection subsystem including an optical sensor configured to collect reflected optical radiation from the area of the scene, and a fused fiber focusing assembly including a fused fiber bundle, a plurality of lenses coupled together and positioned to receive and focus the reflected optical radiation from the area of the scene directly onto the fused fiber bundle, a microlens array interposed between the fused fiber bundle and the optical sensor and positioned to receive the reflected optical radiation from the fused fiber bundle, and a focusing lens positioned to direct the reflected optical radiation from the microlens array onto the optical sensor. The MEMS MMA may be further configured to generate and independently steer multiple beams of optical radiation, at the same or different wavelengths, to more fully interrogate the area of the scene. The MEMS MMA through its Piston capability may be further configured to shape the optical beam(s) to execute a variety of optical functions within the beam steering device.

Digital camera comprising an upright Wide camera configured to provide a Wide image with a Wide image resolution and a folded Tele camera configured to provide a Tele image with a Tele image resolution higher than the Wide image resolution, the Wide and Tele cameras having respective Wide and Tele fields of view FOV.sub.W and FOV.sub.T and respective Wide and Tele image sensors, the digital camera further comprising a rotating OPFE operative to provide a folded optical path between an object or scene and the Tele image sensor, wherein rotation of the OPFE moves FOV.sub.T relative to FOV.sub.W. In some embodiments, a rectangular FOV.sub.T is orthogonal to a rectangular FOV.sub.W. When included in a host device having a user interface that displays FOV.sub.T within FOV.sub.W, the user interface may be used to position FOV.sub.T relative to FOV.sub.W, scan FOV.sub.T across FOV.sub.W and acquire, store and display separate Wide and Tele images, composite Wide plus Tele images and stitched Tele images. The positioning of FOV.sub.T within FOV.sub.W, can be done automatically (autonomously) by continuously tracking an object of interest.