An example particle therapy system may include: a synchrocyclotron to produce a particle beam; a scanner to move the particle beam in one or more dimensions relative to an irradiation target; and an energy degrader that is between the scanner and the irradiation target. The energy degrader may include multiple plates that are movable relative to a path of the particle beam, with the multiple plates each being controllable to move while in the path of the particle beam and during movement of the particle beam. An aperture may be between the energy degrader and the irradiation target. The aperture being may be to trim the particle beam prior to the particle beam reaching the irradiation target.

A volume interrogation system can use an accelerated beam of charged particles to interrogate objects using charged-particle attenuation and scattering tomography to screen items such as portable electronic devices, packages, baggage, industrial products, or food products for the presence of materials of interest inside. The exemplary systems and methods in this patent document can be employed in checkpoint applications to scan items. Such checkpoint applications can include border crossings, mass transit terminals (subways, buses, railways, ferries, etc.), and government and private-sector facilities.

Embodiments of the present invention provide a compact gantry designed to provide particle therapy using a particle beam. A gantry for providing the particle therapy comprises a first dipole magnet operable to bend a particle beam received from a cyclotron by a first degree amount. The gantry further comprises a plurality of quadrupole magnets configured to condition the beam asymmetrically to produce an asymmetric beam, wherein a configuration of the quadrupole magnets is determined using a dispersion function of a second dipole magnet. Further, the second dipole magnet is operable to receive the asymmetric beam and bend the asymmetric beam by a second degree amount, and wherein the second dipole magnet disperses the asymmetric beam to produce a symmetric beam shape at a treatment isocenter or at any other reference point.

Embodiments of the present invention provide a rotational gantry designed to provide proton radiation therapy using a mono-energetic proton beam. The mono-energetic proton beam is transported by a beam line transport system having two or more bending magnets and a plurality of quadrupole and steerer magnets for directing and focusing the proton beam. Energy variation of the beam is performed directly before the beam reaches an isocenter of the gantry.

An irradiation treatment system comprising: a synchrotron ring defining a border extending vertically from the synchrotron ring; a particle beam generator, an output of the particle beam generator coupled to an inlet of the synchrotron ring and arranged to inject charged particle beams into the synchrotron ring; a field control unit arranged to adjust an electric and magnetic field such that the injected charged particle beams are accelerated; a treatment irradiation source positioned within the defined border, the input of the irradiation source coupled to the outlet of the synchrotron ring and arranged to receive the accelerated particle beams from the synchrotron ring; and a patient support member positioned within the defined border and arranged to support a patient in a predetermined relationship with the output of the treatment irradiation source, the treatment irradiation source arranged to irradiate the supported patient with the accelerated particle beams.

A proton beam therapy system with a cantilever gantry. The cantilever gantry has one end portion (the fixed end portion) affixed to an external structure that supports the weight of the gantry. The remainder of the gantry is suspended and the free end portion is coupled to a beam nozzle. A main bearing is coupled to the fixed end portion and enables the gantry to rotate in a full range of 360 around the iso-center. A large counterweight can be disposed in the fixed end portion to keep the system center of mass close to the bearing. The gantry may have a monocoque housing, including a cantilever section enclosing the magnets and other components of the gantry beamline and a drum section on which the bearing is placed.

A gantry-less particle therapy system is provided. Charged particles are extracted from an ion source and accelerated in a beam transport system having an annular portion extending in a first plane and that circumscribes a volume, an arcuate portion extending in a second plane, and a transition portion that connects the annular portion and the arcuate portion. The arcuate portion terminates at a beam nozzle extending radially inward from the annular portion to deliver an ion beam to a treatment area contained in the volume circumscribed by the annular portion.

A proton beam therapy system with a cantilever gantry. The cantilever gantry has one end portion (the fixed end portion) affixed to an external structure that supports the weight of the gantry. The remainder of the gantry is suspended and the free end portion is coupled to a beam nozzle. A main bearing is coupled to the fixed end portion and enables the gantry to rotate in a full range of 360 around the iso-center. A large counterweight can be disposed in the fixed end portion to keep the system center of mass close to the bearing. The gantry may have a monocoque housing, including a cantilever section enclosing the magnets and other components of the gantry beamline and a drum section on which the bearing is placed.

An example particle therapy system may include: a synchrocyclotron to produce a particle beam; a scanner to move the particle beam in one or more dimensions relative to an irradiation target; and an energy degrader that is between the scanner and the irradiation target. The energy degrader may include multiple plates that are movable relative to a path of the particle beam, with the multiple plates each being controllable to move while in the path of the particle beam and during movement of the particle beam. An aperture may be between the energy degrader and the irradiation target. The aperture being may be to trim the particle beam prior to the particle beam reaching the irradiation target.

A particle irradiation system includes three or more scanning magnets that scan a beam in a vertical direction (first direction) or a horizontal direction (second direction) perpendicular to each other. The three or more scanning magnets are configured such that the scanning magnets and the scanning magnets for scanning in the same direction between the vertical direction or the horizontal direction, are disposed in series on a progressing direction axis of a beam, and a volume of a magnetic field feeding region decreases as the scanning magnet is installed at a position farther from an isocenter on the progressing direction axis.