Proton beams are a promising alternative to X-rays for therapeutic purposes because they may also destroy cancer cells, but with a greatly reduced damage to healthy tissue. The energy dose in tissue may be concentrated at the tumor site by configuring the beam to position the Bragg Peak proximate the tumor. The longitudinal range of a proton beam in tissue is generally dependent upon the energy of the beam. However, after switching energies, the proton-beam system requires some time for the beam energy to stabilize before it may be used for therapy. A proton linear accelerator system is provided for irradiating tissue with an improved beam energy control, configured to provide RF energy from a first RF energy source during the on-time of the proton beam operating cycle for changing the energy of the proton beam, and to provide RF energy from a second distinct RF energy source during the off-time of the proton beam operating cycle for increasing or maintaining the temperature of the cavity. Each RF source is operated independently, allowing higher RF pulse rates to reach the cavity, supporting a smaller time between proton beam energy pulses. In addition, the peak power requirements for the second RF energy source may, in general, be less than for the second RF energy source, allowing a less costly type to be used for the second source. The use of a first and second RF source may reduce the cavity settling time from minutes to less than 10 seconds.

A system (12) is proposed for the acceleration of ions to treat Atrial Fibrillation (AF), arteriovenous malformations (AVMS) and focal epileptic lesions; this system (12) includes a pulsed ion source (1), a pre-accelerator (3) and one or more linear accelerators or linacs (5, 6, 7) operating at frequencies above 1 GHz with a repetition rate between 1 Hz and 500 Hz. The particle beam coming out of the complex (12) can vary (i) in intensity, (ii) in deposition depth and (iii) transversally with respect to the central beam direction. The possibility of adjusting in a few milliseconds and in three orthogonal directions, the location of each energy deposition in the body of the patient makes that system of accelerators (12) perfectly suited to irradiation of a beating heart.

A linear accelerator system comprising a source arranged to produce a pulsed beam of charged particles, a linear accelerator string arranged to accelerate the pulsed beam up to a predetermined range of energies, and a pre-acceleration stage interposed between the source and the linear accelerator string and arranged to accelerate the pulsed beam up to an energy suitable for beam insertion into the linear accelerator string and perform bunching of the pulsed beam. An average current detector is arranged to measure an average current in the pulsed beam, the average current detector comprising at least one non-interceptive sensor placed at an input side of the linear accelerator string, downstream of the pre-acceleration stage, the sensor being responsive to the pulsed beam passing thereby.

An apparatus may include an ion source, arranged to generate an ion beam at a first ion energy. The apparatus may further include a DC accelerator column, disposed downstream of the ion source, and arranged to accelerate the ion beam to a second ion energy, the second ion energy being greater than the first ion energy. The apparatus may include a linear accelerator, disposed downstream of the DC accelerator column, the linear accelerator arranged to accelerate the ion beam to a third ion energy, greater than the second ion energy.

A continuous wave ion linear accelerator PET radioisotope system is disclosed. The system includes a high brightness H.sup. ion source, a continuous wave RF quadrupole structure, and continuous wave RF interdigital structures to accelerate the ion beam to about 14 MeV. A high energy beam transport system is also described that includes a photo-detachment beam splitter and a magnet lattice for forming the proton beam into a beam having a Waterbag beam profile. The system also includes one or more targets upon which the proton beam is incident. The targets are either a high power metallic target oriented at about 10 degrees or a low thermal conductivity target oriented at about 35 degrees. The invention includes a method of producing PET isotopes by use of the systems described.

A system (12) is proposed for the acceleration of ions to treat Atrial Fibrillation (AF), arteriovenous malformations (AVMS) and focal epileptic lesions; this system (12) includes a pulsed ion source (1), a pre-accelerator (3) and one or more linear accelerators or linacs (5, 6, 7) operating at frequencies above 1 GHz with a repetition rate between 1 Hz and 500 Hz. The particle beam coming out of the complex (12) can vary (i) in intensity, (ii) in deposition depth and (iii) transversally with respect to the central beam direction. The possibility of adjusting in a few milliseconds and in three orthogonal directions, the location of each energy deposition in the body of the patient makes that system of accelerators (12) perfectly suited to irradiation of a beating heart.

A continuous wave ion linear accelerator PET radioisotope system is disclosed. The system includes a high brightness H.sup. ion source, a continuous wave RF quadrupole structure, and continuous wave RF interdigital structures to accelerate the ion beam to about 14 MeV. A high energy beam transport system is also described that includes a photo-detachment beam splitter and a magnet lattice for forming the proton beam into a beam having a Waterbag beam profile. The system also includes one or more targets upon which the proton beam is incident. The targets are either a high power metallic target oriented at about 10 degrees or a low thermal conductivity target oriented at about 35 degrees. The invention includes a method of producing PET isotopes by use of the systems described.

An apparatus may include an ion source, arranged to generate an ion beam at a first ion energy. The apparatus may further include a DC accelerator column, disposed downstream of the ion source, and arranged to accelerate the ion beam to a second ion energy, the second ion energy being greater than the first ion energy. The apparatus may include a linear accelerator, disposed downstream of the DC accelerator column, the linear accelerator arranged to accelerate the ion beam to a third ion energy, greater than the second ion energy.

An ion implantation apparatus includes: a multistage linear acceleration unit including a plurality of stages of high-frequency resonators and a plurality of stages of focusing lenses; a first beam measuring unit disposed in the middle of the multistage linear acceleration unit and configured to allow passage of a beam portion adjacent to a center of a beam trajectory and measure a current intensity of another beam portion blocked by an electrode body outside a vicinity of the center of the beam trajectory; a second beam measuring unit disposed downstream of the multistage linear acceleration unit and configured to measure a current intensity of an ion beam exiting from the multistage linear acceleration unit; and a control device configured to adjust a control parameter of the plurality of stages of focusing lenses based on measurement results of the first and second beam measuring units.

A superconducting accelerator includes an acceleration cavity, and a refrigerant tank at an outer circumference of the acceleration cavity. The gap between the refrigerant tank and the acceleration cavity is filled with a refrigerant for cooling the acceleration cavity. A pair of pressing members is provided to an outer circumference of the refrigerant tank to be positioned at both side ends of the acceleration cavity in a direction of a beam axis of the charged particle beam or at both ends of the acceleration cavity in a direction perpendicular to the beam axis. A wire is continuously wound around the outer circumference of the refrigerant tank and configured to generate a tensile force in a direction in which the pressing members are brought come into close each other. A tension adjustor is configured to adjust the tensile force generated by the wire.