Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

A microwave generation system comprising a microwave generator, a pulse generator and an impedance network. The pulse generator is arranged to provide pulses of electrical power to the microwave generator and is operable to vary the power of the pulses of electrical power which are provided to the microwave generator. The impedance network is connected between the pulse generator and the microwave generator. The impedance network is switchable so as to substantially match an impedance across the pulse generator according to variations in the impedance of the microwave generator.

An accelerator includes: a plurality of ion sources 221, 222, and 233 that generate a plurality of different types of ions; an electromagnet 11 that generates a magnetic field; and a high frequency cavity 21 that generates a high frequency electric field. The center of an orbit of the ion is eccentric with acceleration, the magnetic field generated by the electromagnet 11 is a magnetic field distribution that decreases outward in a radial direction of the orbit, the high frequency cavity 21 accelerates the ion up to a predetermined energy by the high frequency electric field adjusted to an orbital frequency in response to a nuclide of the incident ion, and a frequency of the high frequency electric field changes following an energy of the ion. Accordingly, it is possible to provide an accelerator and a particle therapy system capable shortening an irradiation time with a small size.

Embodiments of the present invention provide a rotational gantry designed to provide proton radiation therapy using a mono-energetic proton beam. The mono-energetic proton beam is transported by a beam line transport system having two or more bending magnets and a plurality of quadrupole and steerer magnets for directing and focusing the proton beam. Energy variation of the beam is performed directly before the beam reaches an isocenter of the gantry.

The present disclosure provides a neutron capture therapy system. The neutron capture therapy system includes an accelerator, the accelerator generates a charged particle beam; a neutron generator, the neutron generator generates a neutron beam after being irradiated by the charged particle beam; a beam shaping assembly, the beam shaping assembly includes a moderator and a reflector surrounds around the outer periphery of the moderator, the moderator moderates the neutrons generated by the neutron generator to a preset spectrum, and the reflector leads the deflected neutrons back to increase the neutron intensity within the preset spectrum; and a collimator, the collimator concentrates the neutrons generated by the neutron generator; the spectrum of the neutron beam is changed by changing the spectrum of the charged particle beam.

A magnet device that includes upper and lower disk-shaped return yokes, a pair of upper magnetic pole and lower magnetic pole respectively fixed to a disk-shaped surface of the upper return yoke and a disk-shaped surface of the lower return yoke, in which a space to circulate and accelerate an ion beam is formed between the upper magnetic pole and the lower magnetic pole. The upper magnetic pole and the lower magnetic pole have a plurality of concave and convex parts along a track along which the ion beam circulates, are plane-symmetrical with respect to a horizontal symmetry plane formed by the track along which an ion beam circulates, and are plane-symmetrical to one of the vertical planes vertical to the horizontal symmetry plane. Also, the magnetic pole intervals between the concave parts of the upper magnetic pole and the lower magnetic pole are different from each other.

A proton beam therapy system with a cantilever gantry. The cantilever gantry has one end portion (the fixed end portion) affixed to an external structure that supports the weight of the gantry. The remainder of the gantry is suspended and the free end portion is coupled to a beam nozzle. A main bearing is coupled to the fixed end portion and enables the gantry to rotate in a full range of 360 around the iso-center. A large counterweight can be disposed in the fixed end portion to keep the system center of mass close to the bearing. The gantry may have a monocoque housing, including a cantilever section enclosing the magnets and other components of the gantry beamline and a drum section on which the bearing is placed.

A proton therapy system based on a compact superconducting cyclotron, including: a superconducting cyclotron system, an energy selection system, a beam transport system, a fixed therapy room subsystem and a rotating frame therapy subsystem; a fixed-energy proton beam extracted from a superconducting cyclotron of the superconducting cyclotron system is adjusted into a continuous and adjustable proton beam of 70 MeV to 200 MeV by the energy selection system, thus realizing a longitudinal adjustment for a proton range during treating a tumor, and the continuous and adjustable proton beam is respectively transmitted to the fixed therapy room subsystem and the rotating frame therapy subsystem by the beam transport system. The cooperative control of the superconducting cyclotron system, the energy selection system, the beam transport system and the therapy head realizes the transverse expansion of proton beams, thus realizing intensity modulated radiation therapy for the tumor.

A gantry-less particle therapy system is provided. Charged particles are extracted from an ion source and accelerated in a beam transport system having an annular portion extending in a first plane and that circumscribes a volume, an arcuate portion extending in a second plane, and a transition portion that connects the annular portion and the arcuate portion. The arcuate portion terminates at a beam nozzle extending radially inward from the annular portion to deliver an ion beam to a treatment area contained in the volume circumscribed by the annular portion.

A proton beam therapy system with a cantilever gantry. The cantilever gantry has one end portion (the fixed end portion) affixed to an external structure that supports the weight of the gantry. The remainder of the gantry is suspended and the free end portion is coupled to a beam nozzle. A main bearing is coupled to the fixed end portion and enables the gantry to rotate in a full range of 360 around the iso-center. A large counterweight can be disposed in the fixed end portion to keep the system center of mass close to the bearing. The gantry may have a monocoque housing, including a cantilever section enclosing the magnets and other components of the gantry beamline and a drum section on which the bearing is placed.