An ion guide may comprise a set of plate electrodes, each plate electrode having a plurality of apertures formed therethrough. The set of plate electrodes are spatially arranged such that a relative positioning of each plurality of apertures of a respective plate electrode of the set of plate electrodes and respective adjacent plate electrodes of the set of plate electrodes defines a continuous ion flight path through the respective plurality of apertures of each plate electrode of the set of plate electrodes. The continuous ion flight path has a helical-based and/or spiral-based shape.

A multipole with mounting rings arranged on its end faces for mounting the multipole in a mass spectrometer includes two electrode half-shells each having at least two electrodes joinable together by positive-fitting connections on the electrode half-shell longitudinal edges. Each positive-fitting connection includes a fitting and a matching mating fitting, the fitting integrally formed on one electrode half-shell and the mating fitting integrally formed on the other electrode half-shell. Each mounting ring has two mounting ring fittings. One mounting ring fitting can be joined to a mating fitting integrally formed on one of the two electrode half-shells and the other of the two mounting ring fittings can be joined to a mating fitting integrally formed on the other of the two electrode half-shells. Furthermore, a mounting ring for such a multipole has two mounting ring fittings joinable to corresponding mating fittings integrally formed on the electrode half-shells.

The present invention provides an electrode arrangement 10, 10′ for an ion trap, ion filter, an ion guide, a reaction cell or an ion analyser. The electrode arrangement 10, 10′ comprises an RF electrode 12a, 12b, 12a′, 12b′ mechanically coupled to a dielectric material 11. The RF electrode 12a, 12b, 12a′, 12b′ is mechanically coupled to the dielectric material 11 by a plurality of separators 13 that are spaced apart and configured to define a gap between the RF electrode 12a, 12b, 12a′, 12b′ and the dielectric material 11. Each of the plurality of separators 13 comprises a projecting portion 13b and the dielectric material 11 comprises corresponding receiving portions 11a such that on coupling of the RF electrode 12a, 12b, 12a′, 12b′ to the dielectric material 11, the projecting portion 13b of each separator 13 is received within the corresponding receiving portion 11a of the dielectric material 11. The present invention also relates to an ion trap comprises the electrode arrangement 10, 10′ and a method of manufacturing the electrode arrangement 10, 10′.

An ion guide may comprise a set of plate electrodes, each plate electrode having a plurality of apertures formed therethrough. The set of plate electrodes are spatially arranged such that a relative positioning of each plurality of apertures of a respective plate electrode of the set of plate electrodes and respective adjacent plate electrodes of the set of plate electrodes defines a continuous ion flight path through the respective plurality of apertures of each plate electrode of the set of plate electrodes. The continuous ion flight path has a helical-based and/or spiral-based shape.

A mass spectrometer is disclosed comprising a rotatable isolation valve (1) having a curved, spherical, cylindrical or concave portion. At least a portion of an ion guide (2) is positioned so as to extend within a swept volume of the isolation valve (1) enabling the ion guide (2) to be positioned close to a second downstream ion guide (3) and for ions to be transmitted from the first (2) ion guide to the second ion guide (3) with high ion transmission efficiency.

A time-of-flight mass spectrometry device includes: an ion introduction unit; a vacuum chamber connected to the ion introduction unit; a support member provided inside the vacuum chamber; a flight tube having a part of the outer surface supported by the support member and provided inside the vacuum chamber; a temperature sensor provided in the vicinity of a connection portion with the support member of the vacuum chamber; a temperature adjustment element provided in the vicinity of the connection portion; and a temperature control unit that controls the temperature adjustment element based on a measurement result of the temperature sensor.

An ion optical arrangement (1) for use in a mass spectrometer comprises electrodes (11, 12, 14) comprising a multipole arrangement defining an ion optical axis, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is configured for producing a radio frequency electric focusing field for focusing ions on the ion optical axis. The radio frequency electric focusing field has a varying frequency so as to reduce any mass dependence of ion trajectories through the ion optical arrangement. The ion optical arrangement may further be configured for producing a static electric field in response to a DC bias voltage applied to the multipole arrangement. A superimposed varying electric field may be produced by superimposing an AC voltage upon the DC bias voltage.

An ion optical arrangement (1) for use in a mass spectrometer comprises a collision cell defining an ion optical axis along which ions may pass, electrodes comprising a set of parallel poles (11A, 11B, 11C) arranged in the collision cell, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is arranged for switching between a first operation mode in which the collision cell is pressurized and a second operation mode in which the collision cell is substantially evacuated. The ion optical arrangement is further arranged for producing a radio frequency electric focusing field in the first operation mode and a static electric focusing field in the second operation mode.

An ion optical arrangement (1) for use in a mass spectrometer comprises electrodes (11) defining an ion optical path, a housing (18) for accommodating the electrodes, a voltage source for providing voltages to the electrodes to produce electric fields, and a valve for allowing gas to enter and/or leave the housing. The valve comprises an electrostatic mechanism and/or a pneumatic mechanism. The electrostatic mechanism may comprise a flexible foil (30, 31) configured for covering at least one opening (16) in the ion optical arrangement when a first voltage is applied and being spaced apart from the at least one opening when a second voltage is applied. The pneumatic mechanism may comprise a Bourdon tube.

The present invention provides an electrode arrangement 10, 10′ for an ion trap, ion filter, an ion guide, a reaction cell or an ion analyser. The electrode arrangement 10, 10′ comprises an RF electrode 12a, 12b, 12a′, 12b′ mechanically coupled to a dielectric material 11. The RF electrode 12a, 12b, 12a′, 12b′ is mechanically coupled to the dielectric material 11 by a plurality of separators 13 that are spaced apart and configured to define a gap between the RF electrode 12a, 12b, 12a′, 12b′ and the dielectric material 11. Each of the plurality of separators 13 comprises a projecting portion 13b and the dielectric material 11 comprises corresponding receiving portions 11a such that on coupling of the RF electrode 12a, 12b, 12a′, 12b′ to the dielectric material 11, the projecting portion 13b of each separator 13 is received within the corresponding receiving portion 11a of the dielectric material 11. The present invention also relates to an ion trap comprises the electrode arrangement 10, 10′ and a method of manufacturing the electrode arrangement 10, 10′.